Science Inventory

Uncertainty and Variability in Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues and Case Studies (Final Report)

Citation:

U.S. EPA. Uncertainty and Variability in Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues and Case Studies (Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-08/090.

Impact/Purpose:

This report summarizes some of the recent progress in characterizing uncertainty and variability in physiologically-based pharmacokinetic models and their predictions for use in risk assessment.

Description:

EPA announced the availability of the final report, Uncertainty and Variability in Physiologically-Based Pharmacokinetic (PBPK) Models: Key Issues and Case Studies. This report summarizes some of the recent progress in characterizing uncertainty and variability in physiologically-based pharmacokinetic models and their predictions for use in risk assessment.

URLs/Downloads:

Uncertainty and Variability in Physiologically-Based Pharmacokinetic Models: Key Issues and Case Studies   (PDF,10 pp, 68 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (PUBLISHED REPORT/REPORT)
Product Published Date: 09/20/2008
Record Last Revised: 03/22/2017
OMB Category: Influential
Record ID: 198846