Science Inventory

Approaches For the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data In Risk Assessment (Final Report)

Citation:

U.S. EPA. Approaches For the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data In Risk Assessment (Final Report). U.S. Environmental Protection Agency, Washington, D.C., EPA/600/R-05/043F, 2006.

Impact/Purpose:

EPA is releasing a final report describing the evaluation and applications of physiologically based pharmacokinetic (PBPK) models in health risk assessment. This was announced in the September 22 2006 Federal Register Notice.

Description:

EPA released the final report, Approaches for the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data in Risk Assessment as announced in a September 22 2006 Federal Register Notice.This final report addresses the application and evaluation of PBPK models for risk assessment purposes. These models represent an important class of dosimetry models that are useful for predicting internal dose at target organs for risk assessment applications.

Record Details:

Record Type: DOCUMENT ( REPORT)
Product Published Date: 08/31/2006
Record Last Revised: 04/03/2017
Record ID: 157668