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High Throughput Transcriptomics @ USEPA (Toxicology Forum)
Citation:
Martin, M. High Throughput Transcriptomics @ USEPA (Toxicology Forum). Presented at Tox Forum, Salt Lake City, UT, July 28, 2016. https://doi.org/10.23645/epacomptox.5071369
Impact/Purpose:
Slide presentation at the 2016 ToxForum on using High Throughput Transcriptomics at US EPA for broader coverage biological activity space and toxicological MOAs.
Description:
The ideal chemical testing approach will provide complete coverage of all relevant toxicological responses. It should be sensitive and specific It should identify the mechanism/mode-of-action (with dose-dependence). It should identify responses relevant to the species of interest. Responses should ideally be translated into tissue-, organ-, and organism-level effects. It must be economical and scalable. Using a High Throughput Transcriptomics platform within US EPA provides broader coverage of biological activity space and toxicological MOAs and helps fill the toxicological data gap.
URLs/Downloads:
DOI: High Throughput Transcriptomics @ USEPA (Toxicology Forum)
MARTIN EPA HTTR TOXFORUM SALTLAKECITY JULY 2016.PDF (PDF, NA pp, 2201.25 KB, about PDF)