Science Inventory

High Throughput Transcriptomics @ USEPA (Toxicology Forum)

Citation:

Martin, M. High Throughput Transcriptomics @ USEPA (Toxicology Forum). Presented at Tox Forum, Salt Lake City, UT, July 28, 2016. https://doi.org/10.23645/epacomptox.5071369

Impact/Purpose:

Slide presentation at the 2016 ToxForum on using High Throughput Transcriptomics at US EPA for broader coverage biological activity space and toxicological MOAs.

Description:

The ideal chemical testing approach will provide complete coverage of all relevant toxicological responses. It should be sensitive and specific It should identify the mechanism/mode-of-action (with dose-dependence). It should identify responses relevant to the species of interest. Responses should ideally be translated into tissue-, organ-, and organism-level effects. It must be economical and scalable. Using a High Throughput Transcriptomics platform within US EPA provides broader coverage of biological activity space and toxicological MOAs and helps fill the toxicological data gap.

URLs/Downloads:

https://doi.org/10.23645/epacomptox.5071369   Exit

MARTIN EPA HTTR TOXFORUM SALTLAKECITY JULY 2016.PDF   (PDF,NA pp, 2201.25 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (PRESENTATION/SLIDE)
Product Published Date: 07/28/2016
Record Last Revised: 07/17/2017
OMB Category: Other
Record ID: 336953

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY