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Going for Your First Drive in Toxicology: Using the Comptox Chemicals Dashboard
Citation:
Gwinn, M. AND A. Williams. Going for Your First Drive in Toxicology: Using the Comptox Chemicals Dashboard. Presented at Society of Toxicology Annual Meeting Undergraduate Education Presentation, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7889750
Impact/Purpose:
The development of dashboards, supported by their underlying databases and model results, provides an efficient means to assemble, integrate and deliver computational toxicology data and results to inform the assessment of health and ecological risks. The EPA National Center for Computational Toxicology's current portfolio of computational toxicology dashboards is being upgraded and expanded to provide a broader range of data and capabilities related to chemistry, toxicology, toxicokinetics, and exposure. This presentation on the CompTox Chemicals Dashboard will be given at the Society of Toxicology 2019 annual conference Undergraduate Education program.
Description:
The U.S. Environmental Protection Agency (EPA) Computational Toxicology Program integrates advances in biology, chemistry, and computer science to help prioritize chemicals for further research based on potential human health risks. This work involves computational and data driven approaches that integrate chemistry, exposure and biological data. As an outcome of these efforts the National Center for Computational Toxicology (NCCT) has measured, assembled and delivered an enormous quantity and diversity of data for the environmental sciences including high-throughput in vitro screening data, in vivo and functional use data, exposure models and chemical databases with associated properties. The CompTox Chemicals Dashboard is a freely accessible user-friendly web application that provides access to data associated with ~770,000 chemical substances. These data include human and ecological hazard data for tens of thousands of chemicals from multiple databases and peer-reviewed publications. Experimental and predicted physicochemical properties, product and functional use information and bioassay screening data associated with the ToxCast and Tox21 high throughput screening programs are also available. This presentation will provide an overview of the CompTox Chemicals Dashboard and its value to the community as an informational hub. This abstract does not necessarily represent the views or policies of the U.S. Environmental Protection Agency.
URLs/Downloads:
DOI: Going for Your First Drive in Toxicology: Using the Comptox Chemicals Dashboard
GWINN-WILLIAMS - SOT CDI 2019-V2.PDF (PDF, NA pp, 2988.554 KB, about PDF)