Science Inventory

Using high-throughput toxicology to develop tools for regulatory decision-making and screening-level human health risk assessment

Citation:

Paul-Friedman, K. Using high-throughput toxicology to develop tools for regulatory decision-making and screening-level human health risk assessment. Presented at Duke University Risk Assessment Class, Durham, North Carolina, February 12, 2018. https://doi.org/10.23645/epacomptox.7074809

Impact/Purpose:

To help in the education of students at Duke University who are studying environmental and human health risk assessment.

Description:

This presentation gives an overview of how high-throughput toxicology can be used to develop tools that can have regulatory use. First, ToxCast, the toxcast data pipeline, and uncertainties are reviewed. Then, recent successes in building fit-for-purpose tools for Endocrine Disruptor Screening Program prioritization are explained. Then, the talk concludes with a forward look to screening-level risk assessment.

URLs/Downloads:

https://doi.org/10.23645/epacomptox.7074809   Exit

TOXCAST_EDSP21_SCREENING_RA_20180208_DUKERACLASSV2.PDF   (PDF,NA pp, 4733.12 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (PRESENTATION/SLIDE)
Product Published Date: 02/12/2018
Record Last Revised: 09/26/2018
OMB Category: Other
Record ID: 342247

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY