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Using high-throughput toxicology to develop tools for regulatory decision-making and screening-level human health risk assessment
Paul-Friedman, K. Using high-throughput toxicology to develop tools for regulatory decision-making and screening-level human health risk assessment. Presented at Duke University Risk Assessment Class, Durham, North Carolina, February 12, 2018. https://doi.org/10.23645/epacomptox.7074809
To help in the education of students at Duke University who are studying environmental and human health risk assessment.
This presentation gives an overview of how high-throughput toxicology can be used to develop tools that can have regulatory use. First, ToxCast, the toxcast data pipeline, and uncertainties are reviewed. Then, recent successes in building fit-for-purpose tools for Endocrine Disruptor Screening Program prioritization are explained. Then, the talk concludes with a forward look to screening-level risk assessment.
TOXCAST_EDSP21_SCREENING_RA_20180208_DUKERACLASSV2.PDF (PDF,NA pp, 4733.12 KB, about PDF)
Record Details:Record Type: DOCUMENT (PRESENTATION/SLIDE)
Organization:U.S. ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF RESEARCH AND DEVELOPMENT
NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY