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Accelerating the Development and Use of High-Throughput Screening Data for Application to Regulatory Risk Assessments
Citation:
Thomas, R. Accelerating the Development and Use of High-Throughput Screening Data for Application to Regulatory Risk Assessments. Presented at SETAC Focused Topic Meeting on High Throughput Screening and Environmental Risk Assessment, Durham, NC, April 16 - 18, 2018. https://doi.org/10.23645/epacomptox.7054370
Impact/Purpose:
Presentation at the Society of Environmental Toxicology and Chemistry Focused Topic Meeting on High Throughput Screening and Environmental Risk Assessment in Durham NC April 2018
Description:
Goal: Determine whether in vitro bioactivity from broad high-throughput screening studies (e.g., ToxCast) can be used as a conservative point-of-departure and when compared with exposure estimates serve to prioritize chemicals for future study or as lower tier risk assessment. Enabling application of high-throughput data to chemical safety decisions will require delivery and integration using a broad range of IT tools. Partnering with regulators on case studies will increase confidence and accelerate application to chemical risk assessment.
URLs/Downloads:
DOI: Accelerating the Development and Use of High-Throughput Screening Data for Application to Regulatory Risk Assessments
APPLICATION OF HTS DATA TO RA_SETAC_APRIL_2018_V1.PDF (PDF, NA pp, 4454.971 KB, about PDF)