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Predicting Lactational and Early Post-Weaning Exposures in Rats Using Biologically Based Pharmacokinetic Modeling
Citation:
Yoon, M. AND H. A. BARTON. Predicting Lactational and Early Post-Weaning Exposures in Rats Using Biologically Based Pharmacokinetic Modeling. Presented at Society of Toxicology, Seattle, WA, March 16 - 20, 2008.
Impact/Purpose:
The model predictions can be used to help design early life toxicity and pharmacokinetic studies and better interpret study findings, leading to improved risk assessments.
Description:
Risk and safety assessments for early life exposures to environmental chemicals or pharmaceuticals based on cross-species extrapolation would greatly benefit from information on chemical dosimetry in the young.
URLs/Downloads:
MYOON-SOT-2008_FINAL.PDF (PDF, NA pp, 319 KB, about PDF)MYOON-SOT2008 ABS.PDF (PDF, NA pp, 50 KB, about PDF)
Record Details:
Record Type:DOCUMENT( PRESENTATION/ POSTER)
Product Published Date:03/17/2008
Record Last Revised:12/04/2008
OMB Category:Other
Record ID:
191005