Science Inventory

Predicting Age-appropriate Pharmacokinetics of Six Volatile Organic Compounds in the Rat Utilizing Physiologically-based Pharmacokinetic Modeling (T)

Citation:

RODRIGUEZ, C. E. AND H. A. BARTON. Predicting Age-appropriate Pharmacokinetics of Six Volatile Organic Compounds in the Rat Utilizing Physiologically-based Pharmacokinetic Modeling (T) . Presented at Research Triangle Park Drug Metabolism Discussion Group, North Carolina Biotechnology Center, Research Triangle Park, NC, March 01, 2007.

Impact/Purpose:

The capability of physiologically-based pharmacokinetic (PBPK) models to incorporate ageappropriate physiological and chemical-specific parameters was utilized in this study to predict changes in internal dosimetry for six volatile organic compounds (VOCs) across different ages of the rat.

Description:

The capability of physiologically-based pharmacokinetic (PBPK) models to incorporate ageappropriate physiological and chemical-specific parameters was utilized in this study to predict changes in internal dosimetry for six volatile organic compounds (VOCs) across different ages of the rat.

URLs/Downloads:

Predicting Age-appropriate Pharmacokinetics of Six Volatile Organic Compounds in the Rat Utilizing Physiologically-based Pharmacokinetic Modeling (T) Poster   (PDF,NA pp, 113 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (PRESENTATION/POSTER)
Product Published Date: 03/01/2007
Record Last Revised: 12/04/2008
OMB Category: Other
Record ID: 186945