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Per- and Polyfluoroalkyl Substances (PFAS): Reviewing Analytical Methods Data for Environmental Samples: Technical Brief
Citation:
Impellitteri, C., T. Strock, AND J. Willey. Per- and Polyfluoroalkyl Substances (PFAS): Reviewing Analytical Methods Data for Environmental Samples: Technical Brief. U.S. EPA Office of Research and Development, Washington, DC, EPA/600/F-19/056, 2019.
Impact/Purpose:
Provides tips for reviewing from liquid chromatography/tandem mass spectrometry (LC/MS/MS) data generated from per- and polyfluoroalkyl substances (PFAS) analytical methods.
Description:
Interpreting data from analysis of per- and polyfluoroalkyl substances (PFAS) in a variety of environmental sample types can be challenging due to variations in analytical protocols, quality control types and criteria, and data review procedures across laboratories. Analytical chemistry reference methods, both prescriptive and performance-based, are available for laboratories to use as a basis to create standard operating procedures (SOPs) to test for these chemicals; however, results can be difficult to assess, compare, and apply to make site-based decisions. Data reviewers should consider a variety of information when assessing data quality from liquid chromatography/tandem mass spectrometry (LC/MS/MS) analyses, regardless of the method or procedure used. Data quality reviewers should always defer to site and/or state specific data review requirements, where available.