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Enriched housing alters the ventilatory response of male and female ApoE (-/-) mice to a single eucalyptus wildfire smoke exposure
Citation:
Fiamingo, M., S. Toler, K. Lee, W. Oshiro, Todd Krantz, P. Evansky, D. Davies, Ian Gilmour, A. Farraj, AND M. Hazari. Enriched housing alters the ventilatory response of male and female ApoE (-/-) mice to a single eucalyptus wildfire smoke exposure. Society of Toxicology, San Diego, California, March 27 - 31, 2022.
Impact/Purpose:
This study describes the impact of housing conditions on the pulmonary responses of male and female atherosclerotic-prone mice and subsequent effects of wildfire smoke exposure. The impact of non-environmental stressors on health and risk are assessed.
Description:
This study shows that housing enrichment alters basic ventilatory function and pulmonary responses in male versus female mice and may modify the effect of eucalyptus wildfire smoke exposure.