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The Environmental Component of Antimicrobial Resistance: General Background and USEPA Research
Citation:
Garland, J. The Environmental Component of Antimicrobial Resistance: General Background and USEPA Research. Third Country Training program on antimicrobial resistance with Singapore: Panel on environmental AMR, Virtual, Virtual, October 18, 2021.
Impact/Purpose:
Dr. Clara Davis, a State Department colleague that coordinates on antimicrobial resistance work is arranging a Third Country Training program on antimicrobial resistance with Singapore to include panels on human, food, animal, and environmental AMR. The audience is government policy-makers from Asian countries.The participants are working on various issues relevant to AMR policy in Southeast Asia. Many are at various government ministries (Health, Agriculture, Fisheries, Forestry), some are at research institutions. They have a range of backgrounds. The workshop is meant to be an update on current issues in AMR, especially as relevant to the AMR National Action Plans in each country. This talk provided general backgrounmd on the issue of AMR andthe environment as well as an overview of EPA work as part of an interagnecy collaboraiton with FDA, USDA, and CDC. .
Description:
The overall purpose of the Pilot Study is to develop a national-scale, quantitative assessment of AMR within surface water. The four main objectives as developed from initial meetings of the National Antimicrobial Resistance Monitoring System Environmental Working Group (NARMS EWG) are (I) standardized measure (and library of samples) to monitor trends as part of NARMS, (II) provide input to models of AMR risks for various end uses of water (recreational, drinking, agricultural, water reuse), (III) help quantify drivers of occurrence and selective pressures for potential amplification, and (IV) identify critical control points and assess current and new mitigation strategies. Scope of Work. 1) Phase 1: Method development to standardize methods for the analysis of antimicrobial resistant bacterial isolates (E. coli, Enterococcus spp., and Salmonella), antibiotic resistance genes and field collection of surface water samples. 2) Phase 2: Focused study to analyze antimicrobial resistance in the surface waters of a watershed. 3) Phase 3: Probabilistic study to analyze antimicrobial resistance in the surface waters nationwide. 4) Phase 4: Additional focused watershed studies and nation-wide monitoring of antimicrobial resistance in the surface waters.