Science Inventory

Method 559: Determination of Nonylphenol and 4-tert-Octylphenol in Drinking Water by Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Citation:

Tettenhorst, D. AND J. Shoemaker. Method 559: Determination of Nonylphenol and 4-tert-Octylphenol in Drinking Water by Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS). U.S. Environmental Protection Agency, Washington, DC, 2020.

Impact/Purpose:

EPA Method 559 may be used in a future UCMR to gather nationwide occurrence data on nonylphenol and 4-tert-octylphenol and may be used by environmental laboratories to quantitate these chemicals in drinking water.

Description:

Method 559 is an accurate and precise analytical method to determine nonylphenol and 4-tert-octylphenol in drinking water using solid phase extraction and liquid chromatography tandem mass spectrometry (SPE-LC/MS/MS). This method development task establishes sample preservation techniques, sample concentration and analytical procedures, aqueous and extract holding time criteria and quality control procedures. Draft Method 559 has undergone a multi-laboratory verification to ensure other laboratories can implement the method and achieve the quality control measures specified in the method.

URLs/Downloads:

METHOD 559 FINAL.PDF   (PDF, NA pp,  648.075 KB,  about PDF)

Record Details:

Record Type: DOCUMENT ( PUBLISHED REPORT/ METHODOLOGY)
Product Published Date: 09/10/2020
Record Last Revised: 09/14/2020
OMB Category: Other
Record ID: 349691