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Improving Sensitivity and Specificity of Larval Zebrafish Behavior Assays through Identification of Negative Control Chemicals
Citation:
Knapp, B., D. Hunter, M. Lowery, J. Olin, K. Jarema, Z. Rowson, AND S. Padilla. Improving Sensitivity and Specificity of Larval Zebrafish Behavior Assays through Identification of Negative Control Chemicals. Society of Environmental Toxicology and Chemistry (SETAC) North America 44th Annual Meeting November 2023, Louisville, KY, November 12 - 16, 2023. https://doi.org/10.23645/epacomptox.24514156
Impact/Purpose:
Presentation to the Society of Environmental Toxicology and Chemistry (SETAC) North America 44th Annual Meeting November 2023
Description:
Identifying reliable negative control compounds is integral to determining the sensitivity and specificity of chemical exposure assays. This abstract describes the steps taken to identify negative controls to assess chemicals for developmental neurotoxicity potential using screening assays that measure larval zebrafish locomotor behavior in response to visual stimuli.
URLs/Downloads:
DOI: Improving Sensitivity and Specificity of Larval Zebrafish Behavior Assays through Identification of Negative Control Chemicals
SETAC NA POSTER FINAL VERSION 11.6.2023.PDF (PDF, NA pp, 1156.026 KB, about PDF)