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Releasing the Non-targeted Analysis (NTA) Genie to Inform Community Emerging Chemical Exposures
Citation:
Buckley, T., S. Urban, AND Y. Chai. Releasing the Non-targeted Analysis (NTA) Genie to Inform Community Emerging Chemical Exposures. ISES, Chicago, IL, August 27 - 31, 2023.
Impact/Purpose:
N/A
Description:
Session Description. High-resolution mass spectrometry and non-targeted analysis (NTA) methods are transforming chemical exposure assessments providing inroads into the vast space of poorly characterized previously unknown and unmeasured chemicals. This capability captures a chemical space that is on par with the reality of the anthropogenic environmental chemical footprint. NTA provides unique and invaluable information to communities in identifying chemicals of anthropogenic origin warranting additional assessment due to exposure potential. Poly and perfluorinated alkyl substances (PFAS) is a large data poor chemical class that epitomizes both the community environmental health concern and the value and uniqueness of NTA. Although NTA capability is proliferating across the globe, there are significant barriers to adoption to meet community concerns over emerging contaminants. These barriers are especially present within local, state, and regional labs due to entrenchment in traditional targeted methods that underpin regulatory mandates. Yet it is precisely these laboratories where NTA can be most impactful in addressing community concerns. Recognizing the value of NTA for protecting human health and the environment, EPA’s Office of Research and Development is working with a broad range of stakeholders to identify and overcome these barriers. This symposium will aid in the release of the NTA Genie through a discussion of diverse stakeholder perspectives as to motivation, barriers, and solutions to NTA adoption and application to support decisions protecting human health and the environment. Audience Description. This symposium will be of interest to a wide array of stakeholders who share concern over emerging chemical environmental contaminants and have an interest in expanding NTA methods to address this concern. These stakeholders will range from those who are in the business of using NTA to assess emerging contaminants of concern to those who use NTA data to inform decisions protecting public health and the environment. This will include community leaders, local, state, regional, and federal government scientists and decision makers, academics, contract laboratories, software developers, and instrument vendor representatives.