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Development of a New Transcriptomics-Based Assessment Product for Data Poor Chemicals (ToxForum Summer 23)
Citation:
Thomas, R. Development of a New Transcriptomics-Based Assessment Product for Data Poor Chemicals (ToxForum Summer 23). The Toxicology Forum 2023 Summer Meeting, Pentagon City, VA, July 24 - 26, 2023. https://doi.org/10.23645/epacomptox.23751099
Impact/Purpose:
Presentation to The Toxicology Forum—2023 Summer Meeting July 2023 to the session 'US EPA/ORD's Portfolio Approach to Hazard Assessment'.
Description:
The US EPA is obtaining scientific peer-review and public comment on a new draft human health assessment product for data poor chemicals and a case study evaluating the human health and economic trade-offs of the draft assessment product. Three EPA reports are being developed for expert panel review. 1) Scientific support for developing and applying transcriptomic points-of-departure, 2) The standardized methods for running the short-term in vivo transcriptomic studies and developing the ETAP (EPA Transcriptomic Assessment Product), and 3) Socioeconomic case study on the human health and economic value of the ETAP.
URLs/Downloads:
DOI: Development of a New Transcriptomics-Based Assessment Product for Data Poor Chemicals (ToxForum Summer 23)
THOMAS_ETAP_TOXFORUM_JULY 2023_FINAL.PDF (PDF, NA pp, 5395.295 KB, about PDF)