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RAPID TOX application to support Evaluation of chemical toxicity to Listed Species
Citation:
Villeneuve, D., M. Hazemi, C. Lalone, M. Chan, D. Haggard, C. Schaupp, M. Jankowski, AND A. Latier. RAPID TOX application to support Evaluation of chemical toxicity to Listed Species. Center for Computational Toxicology and Exposure monthly science webinar, RTP, NC, November 30, 2022. https://doi.org/10.23645/epacomptox.21681845
Impact/Purpose:
Under section 7(a)(2) of the Endangered Species Act (ESA), interagency consultation is required when a proposed federal action overlaps a listed species range or Designated Critical Habitat. Proposed actions require EPA Regional Offices, like Region 10, to develop Biological Evaluation (BE) documents that assess whether the proposed action is Likely or Not Likely to Adversely Affect listed species. Within R10, the time required to assemble and evaluate relevant toxicity data for a Clean Water Act BE is time-consuming and results in sometimes contentious assessments, thus transparency and consistency are paramount. More efficient methods for gathering and evaluating data from surrogate species that are most appropriate to the assessment could simultaneously improve efficiency and scientific rigor. This presentation describes a custom Data Mart and a pilot software application tentatively branded the "R10 RAPID TOX app" which was developed to bring together multiple CSS data streams relevant to Biological Evaluations (e.g., ECOTOX, ChemProp, ToxVal, TEST, in vitro db). Use of the application is expected to expedite BEs conducted by R10 risk assessors and increase standardization and consistency in how the assessments are performed.
Description:
Webinar presentation for CCTE monthly science webinar, November 30, 2022. The presentation provides an overview of a custom Data Mart and a pilot software application tentatively branded the "R10 RAPID TOX app" which was developed to bring together multiple CSS/CCTE data streams relevant to Biological Evaluations (e.g., ECOTOX, ChemProp, ToxVal, TEST, in vitro db) conducted under the endangered species act. The software application is intended to help improve standardization and consistency in R10 biological evaluations while expediting the review of relevant toxicity information, allowing assessors to more rapidly hone in on toxicity data most applicable to the species and chemicals of interest in their assessment.
URLs/Downloads:
DOI: RAPID TOX application to support Evaluation of chemical toxicity to Listed Species
VILLENEUVE_CCTE SCIENCE WEBINAR 2022-11-30_V2.PDF (PDF, NA pp, 2025.867 KB, about PDF)