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Novel Protein-Protein Interaction Assays for Human Androgen and Estrogen Receptors-Metabolic Retrofit of Androgen Receptor Assay with mRNA Transfection
Citation:
Simmons, Steve. Novel Protein-Protein Interaction Assays for Human Androgen and Estrogen Receptors-Metabolic Retrofit of Androgen Receptor Assay with mRNA Transfection. Joint Research Centre (JRC) & US EPA/ORD/CCTE Mini Endocrine Summit, RTP, NC, December 06, 2021. https://doi.org/10.23645/epacomptox.17208260
Impact/Purpose:
Presentation to the Joint Research Centre (JRC) & US EPA/ORD/CCTE Mini Endocrine Summit December 2021. The purpose of this presentation is to brief scientists at the European Commission's Joint Research Centre of ongoing work related to high-throughput assay development for endocrine-related targets and the retrofitting of assay to include xenobiotic metabolism.
Description:
A short (15 minute) presentation to introduce the design and development of new high-throughput assays to measure activation of estrogen and androgen receptors and a protocol to retrofit these new assay to include xenobiotic metabolism.
URLs/Downloads:
DOI: Novel Protein-Protein Interaction Assays for Human Androgen and Estrogen Receptors-Metabolic Retrofit of Androgen Receptor Assay with mRNA Transfection
2021DEC06_CCTE-JRC_ENDOCRINE SUMMIT_SIMMONS_V2.PDF (PDF, NA pp, 2463.406 KB, about PDF)