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Semi-Quantitative Non-Targeted Analysis as a Rapid Risk Prioritization Tool: A Proof of Concept Using Activated Carbon Drinking Water Filters (Communities of Practice)
Citation:
Groff, L., H. Liberatore, S. Newton, AND J. Sobus. Semi-Quantitative Non-Targeted Analysis as a Rapid Risk Prioritization Tool: A Proof of Concept Using Activated Carbon Drinking Water Filters (Communities of Practice). EPA CompTox Communities of Practice Webinar, Virtual, NC, April 22, 2021. https://doi.org/10.23645/epacomptox.16834243
Impact/Purpose:
Presentation to the EPA CompTox Communities of Practice Webinar April 2021
Description:
This presentation will describe an application of NTA on drinking water filter data obtained via gas chromatography- high-resolution mass spectrometry. The application of semi-quantitative methods to estimate and statistically bound concentrations of known standard contaminants is detailed, as well as a proof-of-concept risk prioritization where solution estimates are extended to media concentration via measured percent recovery data, and then compared to EPA Maximum Contaminant Level data via a novel "Margin of Recovery" approach that allows filtration of an NTA dataset down to a few high-risk chemicals for further targeted analysis. This abstract does not reflect US EPA policy.
URLs/Downloads:
DOI: Semi-Quantitative Non-Targeted Analysis as a Rapid Risk Prioritization Tool: A Proof of Concept Using Activated Carbon Drinking Water Filters (Communities of Practice)
LCGROFF-SEMIQUANTNTA-GCHRMSBRITA-EPACOMPTOXCOP.PDF (PDF, NA pp, 5098.873 KB, about PDF)