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Mutagenicity and Carcinogenicity of Combustion Emissions: Biomarkers & Risk for Cancer
Citation:
DeMarini, D. Mutagenicity and Carcinogenicity of Combustion Emissions: Biomarkers & Risk for Cancer. Monthly seminar series in the School of the Environment at Duke University, Durham, North Carolina, January 30, 2020. https://doi.org/10.23645/epacomptox.11868606
Impact/Purpose:
Combustion emissions, such as those from woodsmoke or coal, are well-documented probable or known human lung carcinogens, and they contribute substantially to the mutagenicity and carcinogenicity of indoor and outdoor air pollution. This presentation reviews 40 years of data on the mutagenicity (in Salmonella and humans) and carcinogenicity (in rodents and humans) of a wide range of combustion emissions. The presentation highlights the 40 years of research from EPA/RTP on this topic and how the results have been used by IARC and other organizations to assess the potential health risks of combustion emissions.
Description:
Presentation given to School of the Environment at Duke University January 2020