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Synthesis of unnatural amino acids via microwave-assisted regio-selective one-pot multi-component reactions of sulfamidates
Citation:
Baig, N. AND R. Varma. Synthesis of unnatural amino acids via microwave-assisted regio-selective one-pot multi-component reactions of sulfamidates. Current Organic Chemistry. Bentham Science Publishers, Ltd., Oak Park, IL, 17(20):2323-2331, (2013).
Impact/Purpose:
Submitted to the Royal Society of chemistry (RSC) journal, Organic and Biomolecular Chemistry
Description:
Synthesis of triazole-based unnatural amino acids, triazole bisaminoacids and β-amino triazole has been described via stereo and regioselective one-pot multi-component reaction of sulfamidates, sodium azide, and alkynes under MW irradiation conditions. The developed method is applicable to a broad substrate scope and has significant potential for the synthesis of triazole modified unnatural amino acids.
URLs/Downloads:
http://dx.doi.org/10.2174/13852728113179990047http://www.ingentaconnect.com/content/ben/coc/2013/00000017/0000
Record Details:
Record Type:DOCUMENT( JOURNAL/ PEER REVIEWED JOURNAL)
Product Published Date:10/01/2013
Record Last Revised:03/31/2014
OMB Category:Other
Record ID:
269159