Science Inventory

Review of Bacillus anthracis Dose Response Data for Human Health Risk Assessment

Citation:

Hines, S. Review of Bacillus anthracis Dose Response Data for Human Health Risk Assessment. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-16/147, 2016.

Impact/Purpose:

The report is designed to support the development of a site-specific human health risk assessment (HHRA) for Bacillus anthracis using available open source data and analysis approaches. The content reflects the output of an agent-specific planning activity for B. anthracis to identify and evaluate published dose-response data, identify data gaps and process gaps for microbial dose-response analysis of the agent, and identify science policy gaps that may need to be filled to conduct a site-specific HHRA for the agent.

Description:

Interest in low-dose dose-response relationships for Bacillus anthracis exposure can be traced to data gaps made apparent during the civilian response to the 2001 anthrax letter event. This report conducts a systematic review of Bacillus anthracis dose-response data that can be used to inform development of a dose-response relationship or to support the use of Bacillus anthracis dose-response data in a human health risk assessment.

URLs/Downloads:

REVIEW OF BACILLUS ANTHRACIS DOSE RESPONSE DATA FOR HUMAN HEALTH RISK ASSESSMENT   (PDF,249 pp, 2552 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (PUBLISHED REPORT/REPORT)
Product Published Date: 06/10/2016
Record Last Revised: 09/11/2019
OMB Category: Other
Record ID: 346590

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL HOMELAND SECURITY RESEARCH CENTER

THREAT AND CONSEQUENCE ASSESSMENT DIVISION