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INCREASED SUSCEPTIBILITY TO PARATHION POISONING FOLLOWING MURINE CYTOMEGALOVIRUS INFECTION
Citation:
Selgrade, M., M. Daniels, J. Illing, A. Ralston, AND M. Grady. INCREASED SUSCEPTIBILITY TO PARATHION POISONING FOLLOWING MURINE CYTOMEGALOVIRUS INFECTION. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-84/194 (NTIS PB85160398).
Description:
Increased Susceptibility to Parathion Poisoning Following Murine Cytomegalovirus Infection. Fifty to 100 percent mortality occurred in mice treated with ordinarily sublethal doses of parathion 2 to 5 days post infection with murine cytomegalovirus (MCMV). These mortalities appeared to be due to an increased sensitivity of infected mice to parathion poisoning. Pentobarbital-induced sleeping time was also enhanced 3 to 6 days post infection and cytochrome P-450 levels were markedly depressed in mice tested 3 days after infection.