You are here:
Development and Evaluation of Novel Dose-Response Models For Use In Microbial Risk Assessment
EPA is announcing the public avalability of the final report Development and Evaluation of Novel Dose-Response Models for Use in Microbial Risk Assessment.
Citation:
U.S. EPA. Development and Evaluation of Novel Dose-Response Models For Use In Microbial Risk Assessment. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-08/033, 2008.
Description:
This document contains a description of dose-response modeling methods designed to provide a robust approach under uncertainty for predicting human population risk from exposure to pathogens in drinking water.
The purpose of this document is to describe a body of literature on a predictive (unconditional) Bayesian framework as an alternative to the currently used approach (variations on ILSI, 2000) to express the risk of infection and illness resulting from exposure to pathogens in drinking water. Secondarily, an alternative to the Poisson distribution for characterizing pathogens in tap water is also described. Together, these new methods may provide a more realistic and rigorous depiction of the impact of water-borne pathogens on drinking water consumers.