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Application of Advances in Exposure Science to Support Chemical Safety Decision Making
Citation:
Dionisio, K. Application of Advances in Exposure Science to Support Chemical Safety Decision Making. International Society of Exposure Science (ISES), Chicago, IL, August 27 - 31, 2023.
Impact/Purpose:
This is an abstract for a presentation for the International Society of Exposure Science (ISES) in August 2023. The theme of the conference is "Connecting Communities and Science through Addressing Environmental Exposures.
Description:
In recent years, chemical safety research has focused on addressing the environmental and health challenge posed by having an insufficient level of information on chemicals necessary to make informed, risk-based decisions. The expansion of databases on chemical use, occurrence, and toxicokinetics has informed exposure modeling efforts, allowing for the prediction of chemical exposures at refined geographic scales and for defined demographic groups. The development of models and tools has further advanced efforts to evaluate chemical safety, including in a real-world context where mixtures (as opposed to single chemicals) are the norm. The greatest impact of these advancements will be realized when data and models are brought together for a specific application, decision context, or to investigate a hypothesis (e.g., spanning scientific domains). Decision makers, risk assessors, and regulators at the community, state, regional, and federal levels have unique and varied needs related to chemical safety decisions, in particular for disproportionately impacted communities. This symposium aims to showcase integrated work efforts in the form of decision-support tools or workflows (e.g., for chemical prioritization), applied case studies incorporating unique decision contexts, or operationalized models or tools currently providing utility in a chemical safety evaluation or risk assessment. Special emphasis will be placed on examples demonstrating support for decision-making in communities impacted by environmental justice concerns, or in sensitive populations (e.g., children).