Related Topics: Health Research

Health Research Products in the Science Inventory

Records 1 to 25 of 4360

Puget Sound Applications of the VELMA Ecohydrological Model (PRESENTATION)
This seminar will present an overview of EPA’s Visualizing Ecosystem Land Management Assessments (VELMA) model and its applications in the Puget Sound Basin. Topics will include a description of how VELMA simulates the interaction of hydrological and biogeochemical processe...
How Visualizing Ecosystem Land Management Assessments (VELMA) modeling quantifies co-benefits and tradeoffs in Community Forest management (PRESENTATION)
The Northwest Community Forest Coalition invited EPA-WED Research Scientist Bob McKane to present the Keynote Address for the 2018 Northwest Community Forest Forum on May 9‐11 in Astoria, OR. His address will describe "How Visualizing Ecosystem Land Management Assessme...
Evaluating the Performance of Household Liquefied Petroleum Gas Cookstoves (JOURNAL)
Liquefied Petroleum Gas (LPG) cookstoves are considered to be an important solution for mitigating household air pollution; however, their performance has rarely been evaluated. To fill the data and knowledge gaps in this important area, laboratory tests (number of tests: 89) wer...
The High Value of IAQ and Buildings (PRESENTATION)
Foundation presentation on the human health and environment value of good indoor air quality and buildings to building owners and managers.
Scaling Factor Variability and Toxicokinetic Outcomes in Children (PRESENTATION)
Abstract title: Scaling Factor Variability and Toxicokinetic Outcomes in ChildrenBackgroundBiotransformation rates (Vmax) extrapolated from in vitro data are used increasingly in human physiologically based pharmacokinetic (PBPK) models. PBPK models are widely used in human hea...
Mitigation of formalin-induced RNA damage to advance whole transcriptomic analyses of archival tissues (PRESENTATION)
Leveraging the use of biorepository samples for genomic analyses holds huge implications for human health, including applications in pathway identification, biomarker discovery, and tumor profiling for precision medicine. However, there is a need for better ways to reduce nucleic...
Get the Lead Out: The Persistent Problem of Lead Exposure from Soil, Dust and Water (PRESENTATION)
The heavy metal lead, a known neurotoxicant, has been used for centuries in a variety of industries and household and consumer products. The choice to use lead reflects its physical/chemical properties including softness, ductility, poor conductibility and resistance to corrosio...
Test Report - CleanCook Model A1 Stove with Alcohol Fuel - Air Pollutant Emissions and Fuel Efficiency (PUBLISHED REPORT)
Test results were obtained in accordance with ISO (International Organization for Standardization) IWA (International Workshop Agreement) 11:2012 that was unanimously affirmed by more than 90 stakeholders at the ISO International Workshop on Cookstoves on February 28-29, 2012 in ...
Differential Effects of Monovalent Cations and Anions on Key Nanoparticle Attributes (PRESENTATION)
Understanding the key particle attributes such as particle size, size distribution and surface charge of both the nano- and micron-sized particles is the first step in drug formulation as such attributes are known to directly influence several characteristics of drugs including d...
An application of the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) frameworks to mechanistically integrate data sources across multiple species into cumulative risk assessment (CRA) (PRESENTATION)
Toxicologists use dose-response data from both in vivo and in vitro experiments to evaluate the effects of chemical contaminants on organisms. Cumulative risk assessments (CRAs) consider the effects of multiple stressors on multiple endpoints, and utilize environmental exposure ...
Application of the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks to advance cumulative risk assessment by integrating human health and ecological endpoints (PRESENTATION)
Evaluating risk of adverse outcomes from chemical exposure is essential for understanding the impacts of environmental contaminants. While human health outcomes are of primary concern and are often the focus of risk assessments, important non-human species are also exposed to co...
Prediction of toxicity and comparison of alternatives using WebTEST (Web-services Toxicity Estimation Software Tool) (PRESENTATION)
A Java-based web service is being developed within the US EPA’s Chemistry Dashboard to provide real time estimates of toxicity values and physical properties. WebTEST can generate toxicity predictions directly from a simple URL which includes the endpoint, QSAR method, and ...
Associations between urban landscape characteristics and Body Mass Index (PRESENTATION)
Obesity is one of the major public-health concerns in many countries today. In the United States, more than 70% of the U.S. adults aged 20 and over are overweight or obese. The prevalence of obesity has been grown rapidly during the last three decades. Obesity prevalence is deter...
Metabolomics Approach for Toxicity Screening of Volatile Substances (PRESENTATION)
In 2007 the National Research Council envisioned the need for inexpensive, high throughput, cell based toxicity testing methods relevant to human health. High Throughput Screening (HTS) in vitro screening approaches have addressed these problems by using robotics. However, the ch...
Novel measurement technologies for ambient and combustion source aerosols (PRESENTATION)
Thie presentaiton examines the chemical properties of atmospheric and combustion source aerosols. It describes the aerosol chemical fractions and the specific chemical constituents in these aerosols. The presentation will cover (i) the limitatins and benefits of hyphenated chroma...
AOP-driven Predictive Models for Carcinogenicity: an exercise in interoperable data application. (PRESENTATION)
Traditional methods and data sources for risk assessment are resource-intensive, retrospective, and not a feasible approach to address the tremendous regulatory burden of unclassified chemicals. As a result, the adverse outcome pathway (AOP) concept was developed to facilitate a ...
In Vitro Toxicity Screening Technique for Volatile Substances Using Flow-Through System@@ (PRESENTATION)
In 2007, the National Research Council envisioned the need for inexpensive, rapid, cell-based toxicity testing methods relevant to human health. in vitro screening approaches have largely addressed these problems by using robotics and automation. However, the challenge is that ma...
A Historical Perspective on the Dichotomy of Arsenic as a Poison and Medicinal Agent (PRESENTATION)
Arsenic is one of the most interesting and enigmatic elements of the periodic table. Its use as an intentional poison has been known for centuries and occasionally occurs today. Arsenic has been called the “King of Poisons”, because it had been used to poison royalt...
Cross-species integration of human health and ecological endpoints into risk assessment using the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks (PRESENTATION)
Exposure to environmental contaminants can influence both human health and ecological endpoints. Chemical risk assessments combine exposure and toxicity data to estimate the likelihood of adverse outcomes for these endpoints, but are rarely conducted in a manner that integrates ...
A case study to illustrate the utility of the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks for integrating human health and ecological data into cumulative risk assessment (PRESENTATION)
Cumulative risk assessment (CRA) methods, which evaluate the risk of multiple adverse outcomes (AOs) from multiple chemicals, promote the use of a conceptual site model (CSM) to integrate risk from relevant stressors. The Adverse Outcome Pathway (AOP) framework can inform these r...
An approach to monitoring cyanobacteria blooms at surface drinking water intakes using satellite imagery (10th National Monitoring Conference) (PRESENTATION)
Cyanobacterial blooms occur worldwide and are associated with human respiratory irritation, undesirable taste and odor of potable water, increased drinking water treatment costs, loss of revenue from recreational use, and human illness as a result of ingestion or skin exposure du...
Modeling Rabbit Responses to Single and Multiple Aerosol Exposures of Bacillus anthracis Spores (HS 4.04.02 - 475) (JOURNAL)
Journal Article
Chemical Mixtures and Epidemiologic Fundamentals for Risk Assessment Applications (PRESENTATION)
Risk management options are increasingly being considered early in the risk assessment process to help scope the considerations and bound the inherent complexities related to potential exposures, risk and future clean-up decisions (including acceptable pollutant levels) related t...
Flood Protection Ecosystem Services in the Coast of Puerto Rico: Associations Between Watershed Processes and Local Human Health and Well Being Indicators (PRESENTATION)
Flood events are becoming increasingly important in coastal cities due to a projected increase in the frequency of extreme weather events. A potential strategy to promote coastal protection from these hazards is the use of green infrastructure to provide flood protection ecosyste...
Ecosystem Goods & Services and their Direct Linkages to Human Health & Well-Being (PRESENTATION)
This presentation provides an overview of the SHC 2.61 Community-Based Final Ecosystem Goods and Services Project and other ecosystem services activities in the Office of Research and Development. Specifically, this presentation addressed a series of topics: Provide an overview ...