Health Research Products in the Science Inventory
Records 1 to
25
of 566
A Literature Review and Data Mining Project to Identify Associations between Stressors and Health Outcomes for Children (PRESENTATION)
Children are often more vulnerable than adults to the effects of environmental contaminants found in their everyday environments. Their dynamic growth and unique interactions with the built, natural, and social environments may result in a greater susceptibility to chemical and n...
PUBLIC COMMENT ON THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2018 FEDERAL PHYSICAL ACITIVTY GUIDELINES (PRESENTATION)
Title: Public Comment on Department of Health and Human Services (DHHS) 2018 Physical Activity Guidelines Author: Wayne E. Cascio, Director, Environmental Public Health Division, US EPA
Abstract: In the 2008 Physical Activity Guidelines, the effects of air pollution and advers...
Studies on the Deposition, Clearance and Toxicity of Combustion Emissions (PRESENTATION)
Seminar on the health impacts of diesel exhaust and biomass combustion emissions
Wildfire smoke exposure and cardiopulmonary hospitalizations among those over age 65 in the United States (PRESENTATION)
Background: The health implications of excess PM2.5 due to wildland fire smoke are not well understood. Very few studies have assessed the effect of wildland fire smoke from multiple fires across the US.
Methods: We estimated daily concentrations of PM2.5 due to wildland fire smo...
An EPA pilot study characterizing fungal and bacterial populations at homes after flooding events at the Martin Peña Channel community-Puerto Rico (PRESENTATION)
The overall objective of this program is to characterize fungal and bacterial populations in the MPC residences in San Juan, Puerto Rico, following flooding events. These profiles will be generated by comparing the fungal and bacterial populations in two groups of residences: hom...
A Collaborative Effort to Assess Environmental Health in Newport News, Virginia (PUBLISHED REPORT)
The Region 3 “Making a Visible Difference in Communities” (MVD) initiative for Southeast Newport News, VA has taken a community-centric, place-based approach to identifying and delivering service to the area’s residents and the city as a whole. Beginning with a ...
Community vulnerability to health impacts of wildland fire smoke exposure (JOURNAL)
Identifying communities vulnerable to adverse health effects from exposure to wildfire smoke may help prepare responses, increase the resilience to smoke and improve public health outcomes during smoke days. We developed a Community Health-Vulnerability Index (CHVI) based on fact...
Assessing the impact of fine particulate matter (PM2.5) on respiratory-cardiovascular chronic diseases in the New York City Metropolitan area using Hierarchical Bayesian Model estimates (JOURNAL)
An enhanced research paradigm is presented to address the spatial and temporal gaps in fine particulate matter (PM2.5) measurements and generate realistic and representative concentration fields for use in epidemiological studies of human exposure to ambient air particulate conce...
Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (Second External Review Draft, Dec 2016) (PUBLISHED REPORT)
This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of sulfur oxides. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primar...
Effects of Source-Apportioned Coarse Particulate Matter (PM) on Allergic Responses in Mice (PRESENTATION)
The Cleveland Multiple Air Pollutant Study (CMAPS) is one of the first comprehensive studies conducted to evaluate particulate matter (PM) over local and regional scales. Cleveland and the nearby Ohio River Valley impart significant regional sources of air pollution including coa...
Effects of Isoprene- and Toluene-Generated Smog on Allergic Inflammation in Mice (PRESENTATION)
Reactions of organic compounds with nitric oxide (NO) and sunlight produce complex mixtures of pollutants including secondary organic aerosol (SOA), ozone (O3), nitrogen dioxide (NO2), and reactive aldehydes. The health effects of these photochemical smog mixtures in susceptible ...
Use of Medicaid and housing data may help target areas of high asthma prevalence (JOURNAL)
Objective: To determine if there was a significant difference between mold contamination and asthma prevalence in Detroit and non-Detroit Michigan homes, between newer and older homes, and if there is a correlation between mold contamination and measures of Medicaid use for asthm...
Air Pollution Exposure Modeling for Health Studies (PRESENTATION)
Dr. Michael Breen is leading the development of air pollution exposure models, integrated with novel personal sensor technologies, to improve exposure and risk assessments for individuals in health studies. He is co-investigator for multiple health studies assessing the exposure ...
Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (External Review Draft, Nov 2015) (PUBLISHED REPORT)
EPA announced the availability of the external review draft of the <em>Integrated Science Assessment for Sulfur Oxides– Health Criteria</em> for public comment and independent peer review in a November 24, 2015 Federal Register Notice. This draft document provides EPA’s evaluati...
Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (Second External Review Draft, 2015) (ASSESSMENT DOCUMENT)
This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of oxides of nitrogen. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current ...
Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (First External Review Draft, 2013) (ASSESSMENT DOCUMENT)
EPA is announcing the availability of the First External Review Draft of the <i>Integrated Science Assessment for Oxides of Nitrogen – Health Criteria</I> for public comment and independent peer review. This draft document provides EPA’s evaluation and synthesis of the most polic...
Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria (Final Report, 2016) (ASSESSMENT DOCUMENT)
This final report provides the U.S. EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of gaseous oxides of nitrogen. It provides a critical part of the scientific foundation for the U.S. EPA’s decision regarding the adequacy of the c...
Field Collection Methods for an EPA Pilot Study Evaluating Personal, Housing, and Community Factors Influencing Children’s Potential Exposures to Indoor Contaminants at Various Lifestages (EPA Pilot Study Add-On to the GreenHousing Study) (PUBLISHED REPORT)
This compilation of field collection standard operating procedures (SOPs) was assembled for the U.S. Environmental Protection Agency’s (EPA) Pilot Study add-on to the Green Housing Study (GHS). A detailed description of this add-on study can be found in the peer reviewed research...
A Citizen-Science Study Documents Environmental Exposures and Asthma Prevalence in Two Communities (JOURNAL)
A citizen-science study was conducted in two low-income, flood-prone communities in Atlanta, Georgia, in order to document environmental exposures and the prevalence of occupant asthma. Teams consisting of a public-health graduate student and a resident from one of the two commun...
B-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant TH2/TH17 responses (JOURNAL)
BackgroundAllergic sensitization to fungi has been associated with asthma severity. As a result, it has been largely assumed that the contribution of fungi to allergic disease is mediated through their potent antigenicity.ObjectiveWe sought to determine the mechanism by which fun...
Populations of some molds in water-damaged homes may differ if the home was constructed with gypsum drywall compared to plaster (JOURNAL)
Starting in the 1940s, gypsum drywall began replacing plaster and lathe in the U.S. home construction industry. Our goal was to evaluate whether some mold populations differ in water- damaged homes primarily constructed with gypsum drywall compared to plaster. The dust samples fr...
Cross-reactivity of Halogenated Platinum Salts (PRESENTATION)
Halogenated platinum (Pt) salts are well-known respiratory sensitizers associated with the development of asthma. People may be exposed to a variety of platinum compounds in different contexts (e.g. occupationally, automobile exhaust). Published reports suggest that sensitizati...
Mouse Model of Halogenated Platinum Salt Hypersensitivity (PRESENTATION)
Occupational exposure to halogenated platinum salts can trigger the development of asthma. Concern for increased asthma risk exists for the general population due to the use of platinum (Pt) in catalytic converters and its emerging use as a diesel fuel additive. To investigate a...
Exposure to metals mixtures: Genomic alterations of infectious disease response pathways in children exposed to environmedntal metals (PRESENTATION)
Exposure to toxic metals can have harmful health effects, particularly in children. Although studies have investigated the individual effects toxic metals have on gene expression and health outcomes, there are no studies assessing the effect of metal mixtures on gene expression p...
Efffect of Aeroallergen Sensitization on Asthma Control in African-American Teens with Persistent Asthma (JOURNAL)
In African-American adolescents with persistent asthma, allergic profile predicted the likelihood of having poorly controlled asthma despite guidelines-directed therapies. Our results suggest that tree and weed pollen sensitization are independent risk factors for poorly controll...