Science Inventory

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Berninger, J., C. LaLone, D. Villeneuve, C. Russom, Joe Tietge, AND G. Ankley. The utility of human ADME data for prioritizing the evaluation of pharmaceuticals in the environment. Presented at Society for Environmental Toxicology and Chemistry, November 11 - 15, 2012.

HORNUNG, M. W., S. J. DEGITZ, J. E. TIETGE, J. J. KORTE, J. HASELMAN, P. A. KOSIAN, A. J. LINDBERG-LIVINGSTON, AND E. M. BURGESS. A Pathway Approach to Predicting Thyroid Hormone Disrupting Activity of Chemicals Using in vitro, ex vivo and in vivo Assays. Presented at International Symposium on Amphibian Endocrinology and Neurobiology, Ann Arbor, MI, July 11 - 13, 2011.

MILLER, D. H., JOE E. TIETGE, M. E. MCMASTER, K. R. MUNKITTRICK, AND X. XIA. Assessment of Population Status for a White Sucker (Catostomus commersoni) Population Exposed to Bleached Kraft Pulp Mill Effluent . Presented at International Association for Great Lakes Research (IAGLR) Conference, Duluth, MN, May 30 - June 03, 2011.

STERNBERG, R., K. R. THOEMKE, J. J. KORTE, S. M. MOEN, J. OLSON, L. KORTE, J. E. TIETGE, AND S. J. DEGITZ. Control of Pituitary Thyroid-stimulating Hormone Synthesis and Secretion by Thyroid Hormones during Xenopus Metamorphosis. GENERAL AND COMPARATIVE ENDOCRINOLOGY. Academic Press Incorporated, Orlando, FL, 173(3):428-437, (2011).

MILLER, D. H., J. E. TIETGE, M. E. MCMASTER, K. R. MUNKITTRICK, X. XIA, AND G. T. ANKLEY. Incorporation of Predictive Population Modeling into the AOP Famework: A Case Study with White Suckers Exposed to Pulp Effluent. Presented at Society of Environmental Toxicology and Chemistry, Boston, MA, November 13 - 17, 2011.

LALONE, C. A., DAN VILLENEUVE, L. BURGOON, J. E. TIETGE, C. L. RUSSOM, AND G. T. ANKLEY. Molecular Target Homology as a Basis for Species Extrapolation to Assess the Ecological Risk of Pharmaceuticals. Presented at International Association of Great Lakes Research, Duluth, MN, May 30 - June 03, 2011.

LALONE, C. A., DAN VILLENEUVE, L. BURGOON, J. E. TIETGE, C. L. RUSSOM, AND G. T. ANKLEY. Molecular Target Homology as a Basis for Species Extrapolation to Assess the Ecological Risk of Veterinary Drugs . Presented at American Chemical Society, Denver, CO, August 28 - September 01, 2011.

KORTE, J. J., R. M. STERNBERG, J. A. SERRANO, K. R. THOEMKE, S. M. MOEN, K. E. LILLEGARD, M. W. HORNUNG, J. E. TIETGE, AND S. J. DEGITZ. Thyroid-stimulating Hormone (TSH): Measurement of Intracellular, Secreted, and Circulating Hormone in Xenopus laevis and Xenopus tropicalis. GENERAL AND COMPARATIVE ENDOCRINOLOGY. Academic Press Incorporated, Orlando, FL, 171(3):319-325, (2011).

BENNETT, R. S., R. J. ERICKSON, D. HOFF, M. W. HORNUNG, R. D. JOHNSON, D. R. MOUNT, J. W. NICHOLS, C. L. RUSSOM, P. K. SCHMIEDER, J. A. SERRANO, J. E. TIETGE, AND D. L. VILLENEUVE. Adverse Outcome Pathways: A Conceptual Framework to Support Ecotoxicology Research and Risk Assessment. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 29(3):730-741, (2010).

TIETGE, J. E. Amphibian Metamorphosis: A Sensitive Life Stage to Chemical and Non-chemical Stressors . Presented at University for Seniors Program, Duluth, MN, January 28, 2010.

TIETGE, J. E., B. C. BUTTERWORTH, J. HASELMAN, G. W. HOLCOMBE, M. HORNUNG, J. J. KORTE, P. A. KOSIAN, S. J. DEGITZ, AND M. WOLFE. Early Temporal Effects of Three Thyroid Hormone Synthesis Inhibitors in Xenopus laevis. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 98(1):44-50, (2010).

SERRANO, J. A., L. HIGGINS, B. A. WITTHUHN, L. B. ANDERSON, G. W. HOLCOMBE, P. A. KOSIAN, J. J. KORTE, J. E. TIETGE, AND S. J. DEGITZ. In vivo Assessment and Potential Diagnosis of Xenobiotics that Perturb the Thyroid Pathway: Proteomic Analysis of Xenopus laevis Brain Tissue following Exposure to Model T4 Inhibitors. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART D: GENOMICS AND PROTEOMICS. Elsevier BV, AMSTERDAM, Netherlands, 5(2):138-150, (2010).

HORNUNG, M. W., S. J. DEGITZ, L. KORTE, J. OLSON, P. A. KOSIAN, A. L. LINNUM, AND J. E. TIETGE. Inhibition of Thyroid Hormone Release from Cultured Amphibian Thyroid Glands by Methimazole, 6-Propylthiouracil, and Perchlorate. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 118(1):42-51, (2010).

TIETGE, J. E., S. J. DEGITZ, J. T. HASELMAN, J. J. KORTE, P. A. KOSIAN, A. J. LINDBERG-LIVINGSTON, E. M. BURGESS, AND M. W. HORNUNG. Inhibition of the Thyroid Hormone Pathway in Xenopus by Mercaptobenzothiazole. Presented at SETAC North America 31st Annual Meeting, Portland, OR, November 07 - 11, 2010.

ANKLEY, G. T., S. J. DEGITZ, M. L. HAASCH, K. M. JENSEN, R. D. JOHNSON, A. W. OLMSTEAD, J. E. TIETGE, AND G. M. CRIPE. Overview of USEPA Tests with Aquatic Vertebrates for Detecting and Assessing Endocrine Disrupting Chemicals. 3rd, Chapter 4, ELDRIDGE, J.C. & Stevens, J.T. (ed.), Endocrine Toxicology. Informa Healthcare Books, UK, London, Uk, , 102-130, (2010).

LALONE, C., DAN VILLENEUVE, J. E. TIETGE, C. L. RUSSOM, AND G. T. ANKLEY. Pharmaceutical Concern and Prioritization Framework for Aquatic Life Effects. Presented at SETAC North America 31st Annual Meeting, Portland, OR, November 07 - 11, 2010.

HORNUNG, M. W., J. E. TIETGE, AND S. J. DEGITZ. Tiered Approach to Thyroid Research Using an Adverse Outcome Pathway Framework. Presented at OECD Workshop on Using Mechanistic Information in Forming Chemical Categories to Fill Data Gaps for Regulatory Purposes, Washington, DC, December 08 - 10, 2010.

HORNUNG, M. W., G. T. ANKLEY, R. S. BENNETT, R. J. ERICKSON, D. HOFF, R. D. JOHNSON, D. R. MOUNT, J. W. NICHOLS, C. L. RUSSOM, P. K. SCHMIEDER, J. A. SERRANO, J. E. TIETGE, AND D. L. VILLENEUVE. Adverse Outcome Pathways: A Conceptual Framework to Support Ecotoxicology Research and Risk Assessment . Presented at 30th Annual Meeting of SETAC North America, New Orleans, LA, November 19 - 23, 2009.

DEGITZ, S. J., M. HORNUNG, AND J. E. TIETGE. Develop a Systems Approach to Characterizing and Predicting Thyroid Toxicity using an Amphibian Model. Presented at EPA B.O.S.C. Computational Toxicology Subcommittee Meeting, Durham, NC, September 29 - 30, 2009.

STERNBERG, R. M., K. R. THOEMKE, J. J. KORTE, S. M. MOEN, J. E. TIETGE, AND S. J. DEGITZ. Negative Feedback Control of Pituitary Thyroid-stimulating Hormone Synthesis and Secretion by Thyroid Hormones during Metamorphosis in Xenopus laevis. Presented at 30th Annual Meeting of SETAC North America, New Orleans, LA, November 19 - 23, 2009.

GRIM, C., M. WOLFE, T. BRAUNBECK, T. IGUCHI, Y. OHTA, L. TOUART, D. C. WOLF, AND J. E. TIETGE. Thyroid Histopathology Assessments for the Amphibian Metamorphosis Assay to Detect Thyroid-active Substances. TOXICOLOGIC PATHOLOGY. Society of Toxicology, RESTON, VA, 37(4):215-424, (2009).

HORNUNG, M. W., J. HASELMAN, G. W. HOLCOMBE, J. J. KORTE, L. KORTE, E. BURGESS, B. C. BUTTERWORTH, P. A. KOSIAN, J. A. SERRANO, J. E. TIETGE, AND S. J. DEGITZ. Interpreting in vivo Effects of Thyroid Synthesis Inhibitors through the Lens of in vitro and ex vivo Assays. Presented at 35th Annual Aquatic Toxicity Workshop, Saskatoon, SK, CANADA, October 05 - 08, 2008.

STERNBERG, R. M., J. J. KORTE, S. M. MOEN, K. R. THOEMKE, AND J. E. TIETGE. Regulation of Thyroid-stimulating Hormone Release from the Pituitary by Thyroxine during Metamorphosis in Xenopus laevis. Presented at SETAC Annual Meeting, Tampa, FL, November 16 - 20, 2008.

DEGITZ, S. J., M. W. HORNUNG, J. J. KORTE, J. OLSON, L. M. KORTE, G. W. HOLCOMBE, P. A. KOSIAN, AND J. E. TIETGE. Development of Thyroid Gland Specific Markers of Hypothalamic-pituitary-thyroid Axis Disruption in the Amphibian Model Species Xenopus laevis. Presented at SETAC Annual Meeting, Milwaukee, WI, November 11 - 15, 2007.

HASELMAN, J., J. E. TIETGE, M. W. HORNUNG, AND S. J. DEGITZ. Development of a High-throughput Method for Quantitating Thyroid Gland Folllicular Cell Hyperplasia in Amphibian Model Species Xenopus laevis. Presented at SETAC Annual Meeting, Milwaukee, WI, November 11 - 15, 2007.