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Records 26 to 50 of 111 records from author Elaina Kenyon

2016
Kenyon, E., C. Eklund, J. Simmons, AND R. Pegram. PBPK-MODEL ESTIMATES OF BROMODICHLOROMETHANE (BDCM) DISTRIBUTION IN URINE AND BLADDER TISSUE. Society of Toxicology, New Orleans, LA, March 12 - 17, 2016.
Kenyon, E., C. Eklund, J. Lipscomb, AND R. Pegram. The impact of variation in scaling factors on the estimation of internal dose metrics: a case study using bromodichloromethane (BDCM). Toxicology Mechanisms and Methods. Taylor & Francis, Inc., Philadelphia, PA, 26(8):620-626, (2016).
2015
Garcia, R., J. Ibrahim, J. Wambaugh, E. Kenyon, AND Woodrow Setzer. Identifiability of PBPK Models with Applications to Dimethylarsinic Acid Exposure. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. Springer, New York, NY, , 1-19, (2015).
Kenyon, E. AND H. Clewell III. Toxicokinetics and Pharmacokinetic Modeling of Arsenic. Edition 1, Chapter 22, J. Christopher States (ed.), Arsenic: Exposure Sources, Health Risks, and Mechanism of Toxicity, edited by J. Christopher States, Chpt. 27, John Wiley & Sons, Inc., Hoboken, NJ. John Wiley & Sons Incorporated, New York, NY, 1:884-908, (2015).
2012
KENYON, E. M., R. A. PEGRAM, C. R. EKLUND, AND J. C. LIPSCOMB. COMPARISON OF IN VIVO DERIVED AND SCALED IN VITRO METABOLIC RATE CONSTANTS FOR SOME VOLATILE ORGANIC COMPOUNDS (VOCS). Presented at Society of Toxicology (SOT) Annual Meeting, San Francisco, CA, March 11 - 15, 2012.
KENYON, E. M. Interspecies Extrapolation. Chapter 19, Brad Reisfeld and Arthur Mayeno (ed.), Computational Toxicology. Humana Press Incorporated, Totowa, NJ, 1:501-520, (2012).
KENYON, E. M. Physiologically based pharmacokinetic (PBPK) modeling considering methylated trivalent arsenicals. Presented at Society of Toxicology Annual Meeting, San Francisco, CA, March 11 - 15, 2012.
2011
KENYON, E. M., T. L. Leavens, C. Eklund, AND R. A. PEGRAM. APPLICATION OF A MULTIROUTE HUMAN PBPK MODEL FOR BROMODICHLOROMETHANE (BDCM). Presented at Society of Toxicology (SOT) Annual Meeting, Washington, DC, March 06 - 10, 2011.
Clewell, H. J., R. S. Thomas, E. M. KENYON, M. F. HUGHES, B. ADAIR, P. R. Gentry, AND J. W. Yager. Concentration-and time-dependent genomic changes in the mouse urinary bladder following exposure to arsenate in drinking water for up to twelve weeks. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 123(2):421-32, (2011).
OSHIRO, W. M., E. M. KENYON, C. J. GORDON, B. Bishop, Q. T. KRANTZ, J. Ford, AND P. J. BUSHNELL. Extrapolating the Acute Behavioral Effects of Toluene from 1-Hour to 24-Hour Exposures in Rats: Roles of Dose Metric, and Metabolic and Behavioral Tolerance. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 123(1):180-92, (2011).
BUSHNELL, P. J., W. M. OSHIRO, Q. T. KRANTZ, C. J. GORDON, E. M. KENYON, AND J. Ford. PREDICTING THE ACUTE BEHAVIORAL EFFECTS OF TOLUENE INHALED FOR 24 HRS IN RATS: DOSE METRICS, METABOLISM AND BEHAVIORAL TOLERANCE. Presented at International Neurotoxicology Association Meeting, X'ian, CHINA, June 05 - 10, 2011.
2010
GORDON, C. J., R. R. GOTTIPOLU, E. M. KENYON, R. THOMAS, M. SCHLADWEILER, C. M. MACK, J. H. SHANNAHAN, G. WALLENBORN, A. NYSKA, R. C. MACPHAIL, J. E. RICHARDS, M. J. DEVITO, AND U. P. KODAVANTI. AGING AND SUSCEPTIBILITY TO TOLUENE IN RATS: A PHARMACOKINETIC, BIOMARKER, AND PHYSIOLOGICAL APPROACH. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 73(4):301-318, (2010).
Boellmann, F., L. Zhang, H. J. Clewell, E. M. KENYON, M. E. Andersen, AND R. S. Thomas. Genome wide analysis of DNA methylation and gene expression changes in the mouse lung following subchronic arsenate exposure. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 117(2):404-417, (2010).
KENYON, E. M., W. M. OSHIRO, C. R. EKLUND, C. Gordon, Q. T. KRANTZ, AND P. J. BUSHNELL. Modeling the toxicokinetics of 24-hour toluene exposure in rats, impact of activity patterns and enzyme induction. Presented at Society of Toxicology 49th Annual Meeting, Salt Lake City, UT, March 07 - 11, 2010.
OSHIRO, W. M., Q. T. KRANTZ, C. J. Gordon, E. M. KENYON, AND P. J. BUSHNELL. Predicting the acute behavioral effects in rats inhaling toluene (or up to 24 hrs: Inhaled vs. internal dose metrics. Presented at Society of Toxicology 49th Annual meeting, Salt Lake City, UT, March 07 - 11, 2010.
OSHIRO, W. M., Q. T. KRANTZ, C. J. GORDON, E. M. KENYON, AND P. J. BUSHNELL. Predicting the acute behavioral effects in rats inhaling toluene for up to 24 hrs: Inhaled vs, internal dose metrics and tolerance. Presented at Neurobehavorial Teratology Society Annual meeting, Louisville, KY, June 25, 2010.
2009
BOYES, W. K., M. S. BERCEGEAY, W. M. OSHIRO, TODD T. KRANTZ, E. M. KENYON, P. J. BUSHNELL, AND V. A. BENIGNUS. Acute Exposure to Perchlorethylene alters Rat Visual Evoked Potentials in Relation to Brain Concentration. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 108(1):159-172, (2009).
HUGHES, M. F., D. J. THOMAS, AND E. M. KENYON. Chapter4: Toxicology and Epidemiology of Arsenic and its Compounds. Chapter 4, Arsenic - Environmental Chemistry, Health Effects and Waste Treatment. John Wiley & Sons, Inc, Hoboken, NJ, 4:237-235, (2009).
KENYON, E. M., T. L. LEAVENS, AND R. A. PEGRAM. Development of a Multiroute Human PBPK Model for Bromodichloromethane (BDCM). Presented at 2009 Annual Society of Toxicology meeting, Baltimore, MD, March 15 - 19, 2009.
BOYES, W. K. AND E. M. KENYON. How pharmacokinetic modeling could improve a risk assessment for manganese. Presented at Society of Risk Analysis 2009 Annual Meeting, Baltimore, MD, December 06 - 09, 2009.
BENIGNUS, V. A., P. Bushnell, W. K. BOYES, C. R. EKLUND, AND E. M. KENYON. Neurobehavorial effects of acute exposure to four solvents: meta-abalyses. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 109(2):295-305, (2009).
2008
EVANS, M. V., S. M. DOWD, E. M. KENYON, M. F. HUGHES, AND H. A. EL-MASRI. A PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODEL FOR intravenous and ingested DIMETHYLARSINIC ACID (DMAV) IN MICE. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 104(2):250-260, (2008).
OSHIRO, W. M., Q. T. KRANTZ, E. M. KENYON, AND P. J. BUSHNELL. ACUTE BEHAVIORAL EFFECTS OF INHALED PERCHLOROETHYLENE IN RATS ARE DIRECTLY RELATED TO ITS CONCENTRATION IN THE BRAIN. Presented at Society of Toxicology, Seattle, WA, March 16 - 20, 2007.
KENYON, E. M., W. T. Klimecki, H. A. EL-MASRI, R. CONOLLY, H. J. CLEWELL, AND B. D. Beck. How Can Biologically-Based Modeling of Arsenic Kinetics and Dynamics Inform the Risk Assessment Process? -- ETD. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 232(3):359-368, (2008).
KENYON, E. M., V. A. BENIGNUS, C. R. EKLUND, J. W. HIGHFILL, W. M. OSHIRO, T. E. SAMSAM, AND P. J. BUSHNELL. MODELING THE TOXICOKINETICS OF INHALED TOLUENE IN RATS: THE IMPACT OF CONDITIONING AND PHYSICAL ACTIVITY. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART A: CURRENT ISSUES. Taylor & Francis, Inc., Philadelphia, PA, 71(4):249-65, (2008).