Science Inventory

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Doering, J., G. Ankley, B. Blackwell, J. Cavalliin, K. Dean, K. Fay, D. Feifarek, K. Jensen, M. Kahl, C. LaLone, S. Poole, E. Randolph, C. Tilton, AND Dan Villeneuve. Cross-species applicability of a quantitative AOP describing inhibition of aromatase activity leading to reproductive dysfunction in fathead minnow. SETAC North America, Sacramento, CA, November 04 - 08, 2018.

Fay, K., Dan Villeneuve, J. Swintek, S. Edwards, M. Nelms, B. Blackwell, AND G. Ankley. Differentiating pathway-specific from nonspecific effects in high-throughput toxicity data: A foundation for prioritizing adverse outcome pathway development. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 163(2):500-515, (2018).

Elonen, C., J. Olker, C. LaLone, D. Hoff, S. Erickson, M. Skopinski, S. Casey, A. Pilli, AND K. Fay. ECOTOX Knowledgebase: New tools for data visualization and database interoperability (poster). SETAC Europe, Rome, ITALY, May 13 - 17, 2018.

Elonen, C., J. Olker, C. LaLone, D. Hoff, S. Erickson, M. Skopinski, C. Horn, S. Casey, K. Fay, AND A. Pilli. ECOTOX Knowledgebase: New tools for data visualization and database interoperability -Poster. Society of Toxicology, San Antoonio, TX, March 11 - 15, 2018.

Fay, K., C. Elonen, D. Hoff, M. Skopinski, A. Pilli, R. Wang, AND C. LaLone. Enhancing the Utility of the ECOTOX knowledgebase (ECOTOX KB) via ontology-based semantics mapping. SETAC Europe, Rome, ITALY, May 14 - 18, 2018.

Fay, K., C. Elonen, D. Hoff, J. Olker, M. Skopinski, A. Pilli, AND C. LaLone. Enhancing the utility of the ECOTOX Knowledgebase via ontology-based annotations. OpenTox USA 2018, Raleigh, NC, July 11 - 12, 2018.

Fay, K., C. Elonen, D. Hoff, M. Skopinski, A. Pilli, R. Wang, AND C. LaLone. Enhancing the utility of the ECOTOX knowledgebase via ontology-based semantics mapping. SETAC North America, Sacramento, CA, November 04 - 08, 2018.

Evich, M., J. Mosley, J. Doering, G. Ankley, K. Fay, Dan Villeneuve, Tim Collette, AND D. Ekman. High-Resolution Mass Spectrometry-based Metabolomics for Translating Exposure Effects Across Species. 2018 SETAC NA Annual Meeting, Sacramento, Ca, November 04 - 08, 2018.

Nichols, J., K. Fay, M. Bernhard, I. Bischof, J. Davis, M. Halder, J. Hu, K. Johanning, H. Laue, D. Nabb, C. Schlechtriem, H. Segner, J. Swintek, J. Weeks, AND M. Embry. Reliability of In Vitro methods used to measure intrinsic clearance of hydrophobic organic chemicals by rainbow trout: Results of an international ring trial. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 164(2):563-575, (2018). https://doi.org/10.1093/toxsci/kfy113

Fay, K., C. LaLone, D. Feifarek, J. Doering, J. Cavallin, Dan Villeneuve, AND G. Ankley. Addressing species diversity in biotransformation: Variability in expressed transcripts of Phase I and II hepatic enzymes among fishes. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.

Fitzsimmons, P., A. Hoffman, K. Fay, AND J. Nichols. Allometric scaling of hepatic biotransformation in rainbow trout. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.

Doering, J., G. Ankley, B. Blackwell, J. Cavallin, K. Fay, D. Feifarek, K. Jensen, M. Kahl, C. LaLone, S. Poole, E. Randolph, AND Dan Villeneuve. Assessment of differences in sensitivity to aromatase inhibitors among freshwater fish species. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.

Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(2):463-471, (2017).

Fay, K., J. Swintek, Dan Villeneuve, S. Edwards, M. Nelms, B. Blackwell, AND G. Ankley. Differentiating pathway-based toxicity from non-specific effects in high throughput data: A foundation for prioritizing targets for AOP development. SETAC North America, Minneapolis, MN, November 12 - 16, 2017.

Cavallin, J., G. Ankley, B. Blackwell, C. Blanksma, K. Fay, K. Jensen, M. Kahl, D. Knapen, Pat Kosian, S. Poole, E. Randolph, A. Schroeder, L. Vergauwen, AND Dan Villeneuve. Impaired swim bladder inflation in early-life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid (article). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(11):2942-2952, (2017).

Cavallin, J., G. Ankley, B. Blackwell, C. Blanksma, K. Fay, K. Jensen, M. Kahl, D. Knapen, Pat Kosian, S. Poole, E. Randolph, A. Schroeder, L. Vergauwen, AND Dan Villeneuve. Impaired swim bladder inflation in early-life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid (presentation). SETAC Midwest Chapter, Minneapolis, MN, March 20 - 22, 2017.

Fay, K., Dan Villeneuve, C. LaLone, Y. Song, K. Tollefsen, AND G. Ankley. Practical approaches to adverse outcome pathway development and weight‐of‐evidence evaluation as illustrated by ecotoxicological case studies . SOCIETY OF ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY JOURNAL. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 36(6):1429–1449, (2017).

Fay, K., P. Fitzsimmons, A. Hoffman, AND J. Nichols. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish. setac north america, Orlando, FL, November 06 - 10, 2016.

Fay, K., G. Ankley, B. Blackwell, S. Edwards, M. Nelms, AND Dan Villeneuve. Differentiating high priority pathway-based toxicity from non-specific effects in high throughput toxicity data: A foundation for prioritizing AOP development. SETAC North America, Orlando, FL, November 06 - 10, 2016.

Cavallin, J., G. Ankley, B. Blackwell, C. Blanksma, K. Fay, K. Jensen, M. Kahl, D. Knapen, Pat Kosian, S. Poole, E. Randolph, A. Schroeder, L. Vergauwen, AND Dan Villeneuve. Impaired swim bladder inflation in early-life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid. SETAC North America, Orlando, FL, November 06 - 10, 2016.

Embry, M., K. Fay, M. Bernard, I. Bischof, J. Davis, J. Domoradzki, M. Halder, J. Hu, K. Johanning, H. Laue, J. Nichols, H. Peterson, C. Schlechtriem, H. Segner, AND J. Weeks. In vitro to in vivo extrapolation of hepatic metabolism in fish: An inter-laboratory comparison of in vitro methods - presentation. SETAC North America, Orlando, FL, November 06 - 10, 2016.

Tan, C., H. El-Masri, S. Edwards, J. Leonard, S. Suarez, AND K. Fay. Integration of chemical-specific exposure and pharmacokinetic information with the chemical-agnostic AOP framework to support high throughput risk assessment. Chemical Safety for Sustainability Subcommittee Meeting, Durham, NC, November 16 - 17, 2016.

Chen, Y., J. Hermens, M. Jonkers, J. Arnot, J. Armitage, T. Brown, J. Nichols, K. Fay, AND S. Droge. Which molecular features affect the intrinsic hepatic clearance rate of ionizable organic chemicals in fish? ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 50:12722-12730, (2016).

Fay, K., D. Nabb, R. Mingoia, I. Bischoff, H. Segner, X. Han, AND K. Johanning. Determination of metabolic stability using cryopreserved hepatocytes from rainbow trout (Oncorhynchus mykiss). Current Protocols in Toxicology. Wiley InterScience, Silver Spring, MD, 65:4.42.1-4.42.29, (2015).

Fay, K., Dan Villeneuve, D. Martinovic-Weigelt, G. Ankley, AND S. Edwards. Enhancing high throughput toxicology - development of putative adverse outcome pathways linking US EPA ToxCast screening targets to relevant apical hazards. SETAC, North America, Salt Lake City, UT, November 01 - 05, 2015.