Science Inventory

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The US EPA has developed a set of annual North American anthropogenic and fire emissions data for criteria air pollutants across 18 broad source catagories for 2002 through 2017.  The sixteen new annual emissions inventories were developed using consistent input data and met...

When “The Principles of Humane Experimental Technique” was published in 1959, authors William Russell and Rex Burch had a modest goal: to make researchers think about what they were doing in the laboratory—and to do it more humanely. Sixty years later, their gro...

Per- and polyfluoroalkyl substances (PFAS) are widely used, and their fluorinated state contributes to unique uses and stability but also long half-lives in the environment and humans. PFAS have been shown to be toxic, leading to immunosuppression, cancer, and other adverse healt...

To identify U.S. lead exposure risk hotspots, we expanded upon geospatial statistical methods from a published Michigan case study. Evaluation of identified hotspots using six lead indices, based on housing age and sociodemographic data, showed moderate-to-substantial agreement w...

The declining trend in vehicle emissions has underscored the growing significance of Volatile Organic Compound (VOC) emissions from Volatile Chemical Products (VCP). However, accurately representing VOC chemistry in simplified chemical mechanisms remains challenging due to its ch...

Global shifts in climatic conditions and anthropogenic disturbances are dramatically modifying the Earth’s ecosystem. Ensuring water security, availability, and quality within this context largely depends on how accurately we can map Global Surface Water Extents (GWSE). Map...

Animal toxicity testing is time and resource intensive, making it difficult to keep pace with the number of substances requiring assessment. Machine learning (ML) models that use chemical structure information and high-throughput experimental data can be helpful in predicting pot...

Read-across is a well-established data-gap filling technique used within analogue or category approaches. Acceptance remains an issue, mainly due to the difficulties of addressing residual uncertainties associated with a read-across prediction and because assessments are expert-d...

Background: Observational epidemiologic studies provide critical data for the evaluation of the potential effects of environmental, occupational and behavioural exposures on human health. Systematic reviews of these studies play a key role in informing policy and practice. System...

Chemical safety assessment begins with defining the lowest level of chemical that alters one or more measured endpoints. This critical effect level, along with factors to account for uncertainty, is used to derive limits for human exposure. In the absence of data regarding the sp...

Communities across the United States and particularly in the Midwest continue to grapple with the complications associated with aging infrastructure. This includes the presence of lead (Pb)-bearing plumbing components such as lead service lines (LSLs), downstream galvanized iron ...

In drinking water distribution systems, including premise plumbing, dissolved oxygen (DO) and free chlorine (FC) are common oxidants and ductile iron (DI) and copper (Cu) are commonly used pipe materials. Microelectrodes are a tool that have been applied in previous corrosion res...

Secondary organic aerosol (SOA) from acid-driven reactive uptake of isoprene epoxydiols (IEPOX) contributes up to 40% of organic aerosol (OA) mass in fine particulate matter. Previous work showed substantial conversions of particulate inorganic sulfates to surface-active organosu...

Bioaccessibility and relative bioavailability of As, Cd, Pb and Sb was investigated in 30 legacy gold mining wastes (calcine sands, grey battery sands, tailings) from Victorian goldfields (Australia). Pseudo-total As concentration in 29 samples was 1.45–148-fold higher than the r...

Communities across the United States are enduring, often unexpectedly, the effects of extreme events, such as excessive heat, prolonged droughts, extreme floods, and wildfires. In places where contaminated sites and waste management facilities are also present, communities must c...

This research investigated the in-situ decay rates of four human wastewater-associated markers (Bacteroides HF183 (HF183), Lechnospiraceae Lachno3 (Lachno3), cross-assembling phage (crAssphage), pepper mild mottle virus (PMMoV) and three enteric viruses (human aden...

Wildland fire is a major global driver in the exchange of aerosols between terrestrial environments and the atmosphere. This exchange is commonly quantified using emission factors or the mass of a pollutant emitted per mass of fuel burned. However, emission factors for microbes a...

Communities across the world are experiencing a myriad of impacts from intensifying extreme heat, flood, drought, and wildfire events due to climate change. Further impacts can be experienced due to nearby contaminated sites and waste management facilities that are either activel...

Combustion of mixed materials during open air burning of refuse or structural fires in the wildland urban interface produces emissions that worsen air quality, contaminate rivers and streams, and cause poor health outcomes including developmental effects. The zebrafish, a freshwa...

Journal article submitted to EcoHealth - (Abstract) - Lyme disease (LD) is the most common vector-borne disease in the United States (U.S.). This paper assesses how climate change may influence LD incidence in the eastern and upper midwestern U.S., and the associated economic bur...

Permafrost soils store ∼50% of terrestrial C, with Yedoma permafrost containing ∼25% of the total C. Permafrost is undergoing degradation due to thawing, with potentially hazardous effects on landscape stability and water resources. Complicating ongoing efforts to project...

Agricultural soils are increasingly undergoing inadvertent and purposeful exposures to engineered CeO2 nanoparticles (NPs), which can impact crops and root-associated microbial communities. However, interactions between NP concentration and exposure duration on plant-mediate...

Extensive research in recent years has reported higher per- and polyfluoroalkyl substance (PFAS) concentrations in municipal solid waste (MSW) landfill leachate than other municipal wastewaters, including multiple studies of leachate from MSW landfills in the United States. Becau...

Background:  Xenobiotic metabolites are widely present in human urine and can indicate recent exposure to environmental chemicals. Proper inference of which chemicals contribute to these metabolites can inform human exposure and risk. Furthermore, longitudinal biomonitoring...

Aqueous film-forming foams (AFFFs) are used in firefighting applications, and often contain per- and polyfluoroalkyl substances (PFAS), which can detrimentally impact environmental and biological health. Incineration is a potential disposal method for AFFFs, which may produce sec...