Science Inventory

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Judson, R., D. Smith, M. Devito, J. Wambaugh, B. Wetmore, K. Friedman, G. Patlewicz, R. Thomas, R. Sayre, J. Olker, S. Degitz, S. Padilla, J. Harrill, T. Shafer, AND K. Carstens. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS). Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25451677

Ledbetter, V., J. Liu, Jessica Hanson, B. Chorley, AND Jon Corton. A Gene Expression Biomarker Identifies Activation of XBP-1 by Chemical Inducers of the Unfolded Protein Response (UPR) in a Gene Expression Compendium. SOT, Salt Lake City, UT, March 11 - 14, 2024. https://doi.org/10.23645/epacomptox.25534159

Beardwood, A., C. Wigand, S. Ayvazian, D. Cobb, Philip Colarusso, AND N. Schafer. A Narragansett Bay Mesocosm Experiment: Effects of Eelgrass Density on Greenhouse Gas Fluxes. New England Estuarine Research Society (NEERS) Spring Meeting, Freeport, ME, April 18 - 20, 2024.

Martos, S., S. Simmons, AND K. Slentz-Kesler. A New Approach Method for T Cell Immunotoxicity Using CD3/CD28 Co-stimulation and IL-2 NanoLuc Luciferase Reporter. Presented at SOT Conference 2024: A New Approach Method (NAM) to Screen for the Impact of Endogenous Stress on Chemical Toxicity, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25533373

O'Shaughnessy, Katherine, A. Sasser, AND K. Bell. A Novel Histological Method to Detect Abnormal Thyroid Hormone Action in the Developing Rat Brain. Annual Society of Toxicology Meeting, Salt Lake City, UT, March 10 - 14, 2024.

Kruse, P. AND C. Ring. A cheminformatics workflow for higher-throughput modeling of chemical exposures from biosolids (SOT 2024). SOT, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25400200

Patlewicz, G., A. Williams, M. Adams, I. Shah, AND K. Friedman. A cheminformatics workflow to select representative TSCA chemicals for New Approach Methodology (NAM) screening. SOT, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25395526

Corton, Jon, V. Ledbetter, S. Cohen, E. Atlas, C. Yauk, AND J. Liu. A transcriptomic biomarker predictive of cell proliferation for use in adverse outcome pathway-informed testing (SOT 24). Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, NV, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25443715

Alewel, D., K. Rentschler, M. Schladweiler, S. Gavett, C. Miller, T. Jackson, P. Evansky, AND U. Kodavanti. Adrenergic receptor antagonists modulate acrolein-induced ventilatory changes, upper respiratory inflammation, and cytokine release. Society of Toxicology, Salt Lake City, UT, March 10 - 14, 2024.

Britton, K., R. Judson, K. Jarema, J. Olin, B. Hill, B. Knapp, M. Lowery, M. Feshuk, J. Brown, AND S. Padilla. Analysis of the Developmental Toxicity Profile of Per- and Polyfluoroalkyl Substances (PFAS) Using a Larval Zebrafish Assay. Carolinas SETAC 2024 Annual Meeting, Boone, NC, April 14 - 16, 2024. https://doi.org/10.23645/epacomptox.25757805

Ruto, B., S. Waidyanatha, J. Blake, R. Fernando, AND D. Jenkins-Hill. Anatoxin-a: formulation and stability in support of rodent studies. Society of Toxicology, Salt Lake City, UT, March 11 - 14, 2024.

Wambaugh, J., R. Tornero-Velez, M. Devito, C. Lau, AND B. Wetmore. Applying High Throughput Toxicokinetics (HTTK) to Per- and Polyfluoro Alkyl Substances (PFAS). SOT, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25408537

Clark, B., Y. Rericha, D. Glinski, C. Christen, M. Francoeur, H. Schrader, L. Mills, W. Henderson, C. Lavelle, M. Cantwell, AND D. Nacci. Assessing the effects of dietary exposure to PFOS and PFHxS in mummichogs (Fundulus heteroclitus). PRIMO22, Nantes, FRANCE, May 26 - 29, 2024.

Coefield, S. Building Factors Influencing Indoor Air Quality During Wildfire Smoke Events. Wildland Fire Leadership Council Meeting, Atlanta, GA, March 05 - 06, 2024.

Patlewicz, G., A. Ross, H. Bledsoe, J. Vidal, L. Groff, B. Hagan, AND I. Shah. Building a compendium of expert driven read-across cases to facilitate an analysis of the contribution that different similarity contexts play in read-across performance. SOT, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25395676

Speen, A., C. Love, Yong Ho Kim, Matthew Gilmour, I. Jaspers, S. Vance, AND S. Gavett. Burn Pit-Related Smoke Activates Respiratory Epithelial Oxidative Stress Response Pathways. 2024 Society of Toxicology, Salt Lake City, UT, March 10 - 14, 2024.

Strader, R., S. Padilla, Yong Ho Kim, D. Hunter, J. Smoot, K. Britton, B. Knapp, W. Oshiro, M. Hazari, M. Hays, W. Preston, I. jaspers, Matthew Gilmour, AND A. Farraj. Burn Pit-related Smoke Causes Acute Irritant Responses in Zebrafish that Vary by Fuel Type. 18th International Congress on Combustion Byproducts and Health Effects, Durham, NC, May 19 - 21, 2024.

Fitzpatrick, H., K. Wallace, T. Freudenrich, M. Mayil Vahanan, AND K. Carstens. Characterization of signaling pathways in in vitro developmental neurotoxicity battery. SOT Conference 2024: A New Approach Method (NAM) to Screen for the Impact of Endogenous Stress on Chemical Toxicity, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25431925

Fitzpatrick, H., K. Wallace, T. Freudenrich, M. Mayil Vahanan, K. Carstens, AND T. Shafer. Characterization of signaling pathways in in vitro developmental neurotoxicity battery (TSfN). Presented at 9th Annual Triangle Society for Neuroscience (TSfN), Durham, NC, April 26, 2024.

Klein, L., Yong Ho Kim, Joseph Pancras, A. Johnstone, W. Williams, M. Schladweiler, W. Oshiro, Matthew Gilmour, AND S. Gavett. Chemical composition and size of anthropogenic particulate matter affect biological responses in a rodent model. 2024 Society of Toxicology, Salt Lake City, UT, March 10 - 14, 2024.

Markwiese, James. Climate and Pacific Northwest fires: EPA research on air and water quality. 2024 NATIONAL TRIBAL LEADERS CLIMATE SUMMIT, Seattle, WA, April 15 - 17, 2024.

Olson, N., Annie Matsler, L. Moorhead, R. Panko, J. Penry, AND C. Ridley. Climate, greenspace, and community health: A discussion of decision-relevant knowledge and priorities. National Adaptation Forum 2024, St. Paul, MN, May 14 - 16, 2024.

Huber, E., O. Rice, L. Dailey, J. Murray, AND S. McCullough. Common Liquid Application Dosing Conditions Alter Toxicity Testing Endpoints in Air-Liquid Interface Primary Human Bronchial Epithelial Cultures. Society of Toxicology, Salt Lake City, UT, March 10 - 14, 2024.

Carstens, K., E. Gronskaya, D. Jaeckel, T. Shafer, M. Zurich, AND D. Pamies. Comparison of a high-density microelectrode array (MEA) assay for neurotoxicity screening using a 3D human iPSC-derived brain organoid model versus a 2D rat cortical cell model. International Conference on Developmental Neurotoxicity Testing (DNT5), Konstanz, GERMANY, April 07 - 10, 2024. https://doi.org/10.23645/epacomptox.25742760

Thomas, R., M. Hawks, J. Ford, AND M. Gilbert. Deiodinase metabolism of thyroid hormones as measured by LC-MS/MS is altered by exposure to iopanoic acid in a rodent model. Society of Toxicology, Salt Lake City, UT, March 10 - 14, 2024.