Science Inventory

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Thomas, R., M. Hawks, J. Ford, AND M. Gilbert. Deiodinase metabolism of thyroid hormones as measured by LC-MS/MS is altered by exposure to iopanoic acid in a rodent model. Society of Toxicology, Salt Lake City, UT, March 10 - 14, 2024.

Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, Kristina Chialton, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, AND W. Casey. EPA Transcriptomic Assessment Product (ETAP) for Perfluoro-3-Methoxypropanoic Acid. U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-24/066, 2024. https://doi.org/10.23645/epacomptox.25352962

Conley, J., C. Lambright, N. Evans, J. Bangma, J. Ford, D. Jenkins-Hill, AND L. Gray. Maternal, fetal, and neonatal toxicity of the long-chain, multi-ether PFAS PFO5DoA in the Sprague-Dawley rat. Society of Toxicology 2024 Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.

Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, K. Thayer, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, W. Casey, R. Sams, S. Hunter, W. Cascio, K. Holt, S. Jones, R. Subramaniam, G. Rice, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Standard Methods for Development of EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/083, 2024. https://doi.org/10.23645/epacomptox.25365496

Macmillan, D., J. Ford, L. Gray, AND J. Conley. Comparative Metabolomics of Short-term Maternal Gestational Exposure of Rats to Emerging Perfluoroalkyl Ether Carboxylic Acids. Dioxin 2023, Maastricht, NETHERLANDS, September 10 - 14, 2023. https://doi.org/10.23645/epacomptox.24066012

Jarnagin, A., E. Korol-Bexell, A. Brennan, J. Ford, J. Wambaugh, D. Macmillan, M. Hughes, AND B. Wetmore. Cross Species Comparisons of Toxicokinetic Parameters for In Vitro-In Vivo Correlation Analyses. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22294393

Decrane, R., T. Stoker, A. Murr, J. Ford, AND H. El-Masri. Cross species extrapolation of the disruption of thyroid hormone synthesis by oxyfluorfen using in vitro data, physiologically based pharmacokinetic (PBPK), and thyroid hormone kinetics models. Current Research in Toxicology. Elsevier B.V., Amsterdam, Netherlands, 5:100138, (2023). https://doi.org/10.1016/j.crtox.2023.100138

Sasser, A., K. Bell, J. Ford, M. Gilbert, AND K. O'Shaughnessy. Developmental Hypothyroidism: An Underappreciated Risk Factor of Brain Barrier Disruption. Society of Toxicology, Nashville, TN, March 19 - 23, 2023.

Renyer, A., K. Ravindra, B. Wetmore, J. Ford, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Dose Response, Dosimetric, and Metabolic Evaluations of Replacement PFAS Perfluoro-(2,5,8-trimethyl-3,6,9-trioxadodecanoic) Acid (HFPO-TeA). Toxics. MDPI, Basel, Switzerland, 11(12):951, (2023). https://doi.org/10.3390/toxics11120951

Conley, J., C. Lambright, N. Evans, A. Dixon, J. Ford, D. Jenkins-Hill, E. Hines, J. McCord, E. Medlock Kakaley, AND L. Gray. Dose addition-based approaches accurately predict maternal and neonatal effects in Sprague-Dawley rats from three different PFAS mixtures studies. Society of Toxicology 2023 Annual Meeting, Nashville, TN, March 19 - 23, 2023.

Brennan, A., S. Shaut, A. Renyer, R. Payne, J. Ford, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Identification of Biotransformation Products (BPs) in Rats Exposed to 6:1 Fluorotelomer Alcohol (6:1 FTOH). SETAC, Louisville, KY, November 12 - 16, 2023. https://doi.org/10.23645/epacomptox.24526438

Gilbert, M., K. Bell, M. Hawks, AND J. Ford. Impaired Inhibitory Hippocampal Network Function in Adult Rats Exposed Developmentally to Perchlorate and Dietary Iodine Deficiency. Society of Toxicology, Nashville, TN, March 19 - 23, 2023.

Decrane, R., T. Stoker, A. Murr, J. Ford, AND H. El-Masri. In vitro to In vivo (IVIVE) and Species Extrapolation for the Disruption of Thyroid Hormone Synthesis by Oxyfluorfen using Physiologically Based Pharmacokinetic (PBPK) and Thyroid Hormones Kinetics Models. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22211938

Thomas, R., K. Bell, C. Riutta, M. Hawks, J. Ford, AND M. Gilbert. Prevalence of Periventricular Heterotopia within Adult Rats Following Developmental Exposure to Perchlorate and Dietary Iodine Deficiency. Developmental Neurotoxicology Society (DNTS), Charleston, SC, June 24 - 28, 2023.

Gilbert, M., J. Ford, C. Riutta, K. OShaughnessy, AND P. Kosian. Reducing Uncertainties in Quantitative Adverse Outcome Pathways by Analysis of Thyroid Hormone in the Neonatal Rat Brain. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 193(2):192-203, (2023). https://doi.org/10.1093/toxsci/kfad040

Hawks, M., K. Bell, R. Thomas, J. Ford, AND M. Gilbert. Reductions in Neocortical Parvalbumin Expression Due to Iodine Deficiency and Ammonium Perchlorate Exposure. Developmental Neurotoxicology Society (DNTS), Charleston, SC, June 24 - 28, 2023.

Gilbert, M., Katherine O'Shaughnessy, K. Bell, AND J. Ford. Structural Malformations in the Neonatal Rat Brain Accompany Developmental Exposure to Ammonium Perchlorate. Toxics. MDPI, Basel, Switzerland, 11(12):1027, (2023). https://doi.org/10.3390/toxics11121027

Ford, J. AND M. Gilbert. Targeted Proteomics Analysis for Parvalbumin in Rat Brain Tissue. Development and Neuro Tox Conference, Charleston, SC, June 24 - 28, 2023.

O'Shaughnessy, Katherine, B. McMichael, A. Sasser, K. Bell, C. Riutta, J. Ford, T. Stoker, R. Grindstaff, A. Pandiri, AND M. Gilbert. Thyroid Hormone Action Controls Multiple Components of Cell Junctions at the Ventricular Zone in the Newborn Rat Brain. Frontiers in Endocrinology. Frontiers, Lausanne, Switzerland, 14:1090081, (2023). https://doi.org/10.3389/fendo.2023.1090081

Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, A. Dixon, D. Jenkins-Hill, J. McCord, M. Strynar, J. Ford, AND L. Gray. Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 170:107631, (2022). https://doi.org/10.1016/j.envint.2022.107631

Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, J. Ford, J. McCord, M. Strynar, AND E. Gray. Evaluation of dose additive effects of combined oral maternal exposure to PFOA and PFOS during pregnancy in the Sprague-Dawley rat. 2022 Society of Toxicology Annual Meeting, San Diego, CA, March 27 - 31, 2022.

Hawks, M., T. Stoker, A. Murr, J. Ford, C. Wood, T. Beasley, A. Yackley, D. Jenkins-Hill, AND M. Gilbert. Gestational Exposure To Oxyfluorfen, A Newly-Identified Thyroid Disruptor: Effects In Pregnant Rats And Their Progeny. NC Society of Toxicology Annual Meeting, Durham, NC, October 18, 2022.

Gilbert, M., I. Hassan, C. Wood, Katherine O'Shaughnessy, S. Spring, S. Thomas, AND J. Ford. Gestational Exposure to Perchlorate in the rat: Thyroid Hormones in Fetal Thyroid Gland, Serum, and Brain. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(1):117-130, (2022). https://doi.org/10.1093/toxsci/kfac038

Gilbert, M., I. Hassan, C. Wood, K. OShaughnessy, S. Spring, S. Thomas, AND J. Ford. Gestational Exposure to the NIS Inhibitor Ammonium Perchlorate – Thyroid Hormones in Gland, Serum, Fetal Rat Brain. Society of Toxicology, San Diego, California, March 27 - 31, 2022.

Brennan, A., L. Albrecht, M. Phillips, J. Ford, B. Wetmore, L. Wehmas, M. Hughes, AND M. Devito. In-vivo and in-vitro quantitation and stability of fluorotelomer compounds in rat and human plasma to inform toxicity. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19376039