Science Inventory

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Chang, D., J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, G. Patlewicz, R. Thomas, L. Wehmas, K. Vitense, S. Auerbach, W. Casey, R. Sams, S. Hunter, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/084, 2024. https://doi.org/10.23645/epacomptox.25365550

Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, K. Thayer, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, W. Casey, R. Sams, S. Hunter, W. Cascio, K. Holt, S. Jones, R. Subramaniam, G. Rice, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Standard Methods for Development of EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/083, 2024. https://doi.org/10.23645/epacomptox.25365496

Wambaugh, J., T. Barton-Maclaren, M. Beal, M. Devito, J. Dorne, S. Ferguson, M. Hughes, R. Judson, A. Long, I. Moffat, K. Paul-Friedman, S. Stavroula, R. Thomas, AND B. Wetmore. APCRA Case Study: High Throughput Toxicokinetics for In Vitro-In Vivo Extrapolation. APCRA 7, Helsinki, FINLAND, April 25 - 27, 2023. https://doi.org/10.23645/epacomptox.22647385

Jarnagin, A., E. Korol-Bexell, A. Brennan, J. Ford, J. Wambaugh, D. Macmillan, M. Hughes, AND B. Wetmore. Cross Species Comparisons of Toxicokinetic Parameters for In Vitro-In Vivo Correlation Analyses. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22294393

Brennan, A., S. Shaut, A. Renyer, R. Payne, J. Ford, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Identification of Biotransformation Products (BPs) in Rats Exposed to 6:1 Fluorotelomer Alcohol (6:1 FTOH). SETAC, Louisville, KY, November 12 - 16, 2023. https://doi.org/10.23645/epacomptox.24526438

Wambaugh, J., M. Beal, M. Devito, S. Ferguson, M. Hughes, R. Judson, I. Moffat, A. Nong, A. Paini, K. Paul-Friedman, R. Thomas, AND B. Wetmore. Characterizing High Throughput Toxicokinetics for Chemical Decision Making. ISES, Lisbon, N/A, PORTUGAL, September 25 - 29, 2022. https://doi.org/10.23645/epacomptox.21126658

Cook, C., L. Albrecht, G. Cary, B. Edwards, D. Haggard, N. Hanley, M. Hughes, A. Jarnagin, T. Kodavanti, E. Korol-Bexell, A. Kreutz, M. Ngo, C. Patullo, C. Ring, R. Sayre, B. Sharma, J. Wall, H. Yamazaki, AND J. Wambaugh. EPA’s Concentration versus Time Database: A Resource for Extrapolating Toxicokinetic Trends Across Chemicals. Society of Toxicology, San Diego, California, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.18624749

Cook, C., L. Albrecht, G. Cary, B. Edwards, D. Haggard, N. Hanley, M. Hughes, A. Jarnagin, T. Kodavanti, E. Korol-Bexell, A. Kreutz, M. Ngo, C. Patullo, C. Ring, R. Sayre, B. Sharma, J. Wall, H. Yamazaki, AND J. Wambaugh. EPA’s Concentration versus Time Database: A resource for extrapolating toxicokinetic parameters across chemicals. North Carolina Society of Toxicology, Virtual, North Carolina, January 19, 2022. https://doi.org/10.23645/epacomptox.18624749

MacMillan, D., A. Renyer, M. Smeltz, M. Phillips, K. Ravindra, M. Devito, M. Hughes, L. Wehmas, AND B. Wetmore. Evaluations of in vivo and in vitro dosimetry and metabolic biotransformation of the hexafluoropropylene oxide homologue HFPO-TeA, an emerging per-and polyfluoroalkyl substance (PFAS). SETAC, Pittsburgh, PA, November 13 - 17, 2022. https://doi.org/10.23645/epacomptox.21552594

Brennan, A., L. Albrecht, M. Phillips, J. Ford, B. Wetmore, L. Wehmas, M. Hughes, AND M. Devito. In-vivo and in-vitro quantitation and stability of fluorotelomer compounds in rat and human plasma to inform toxicity. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19376039

Renyer, A., D. MacMillan, M. Devito, M. Hughes, AND L. Wehmas. Internal Dose and In-Life Results of Perfluoro-2,5,8-trimethyl-3,6,9-trioxadodecanoic acid Exposure from Short Term Dosing Studies in Rats. ASMS Conference on Mass Spectrometry and Allied Topics, Minneapolis, MN, June 05 - 09, 2022. https://doi.org/10.23645/epacomptox.19890808

Renyer, A., D. MacMillan, M. Devito, M. Hughes, AND L. Wehmas. Internal dose of perfluoro-3-methoxypropanoic acid in rat plasma and in-life effects from short term dosing studies. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19341683

MacMillan, D., A. Renyer, M. Devito, M. Hughes, AND L. Wehmas. Nontargeted analysis for identification of PFAS biotransformation products in rat plasma. American Society for Mass Spectrometry Conference, Minneapolis, MN, June 05 - 09, 2022. https://doi.org/10.23645/epacomptox.19908283

MacMillan, D., A. Renyer, M. Devito, M. Hughes, AND L. Wehmas. Nontargeted analysis for identification of PFAS biotransformation products in rat plasma. SETAC NTA, Durham, NC, May 22 - 26, 2022. https://doi.org/10.23645/epacomptox.19758634

Clapper, H., Getachew E. Tedla, K. Rogers, AND M. Hughes. Simulated Gastric Leachate of 3D Printer Metal-Containing Filaments Induces Cytotoxic Effects in Rat and Human Intestinal Models. ASCCT, Chapel Hill, NC, October 19 - 21, 2022. https://doi.org/10.23645/epacomptox.21330663

Wambaugh, J., T. Barton-Maclaren, M. Beal, M. Devito, J. Dorne, S. Ferguson, M. Hughes, R. Judson, I. Moffat, A. Nong, A. Paini, K. Paul-Friedman, R. Thomas, AND B. Wetmore. APCRA Case Study:High Throughput Toxicokinetics for In Vitro-In Vivo Extrapolation. Accelerating the Pace of Chemical Risk Assessment (APCRA) meeting, Virtual, NC, October 14 - 15, 2021. https://doi.org/10.23645/epacomptox.16828510

Hughes, M., H. Clapper, R. Burgess, AND K. Ho. Human and ecological health effects of nanoplastics: May not be a tiny problem. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, Netherlands, 28:43-48, (2021). https://doi.org/10.1016/j.cotox.2021.09.004

Renyer, A., D. MacMillan, M. Devito, M. Hughes, AND L. Wehmas. Internal Dose of Selected PFAS (Perfluoro-3-methoxypropanoic acid and) in Rat Plasma from Short Term Dosing Studies. 69th Annual American Society for Mass Spectrometry (ASMS) Conference, Philadelphia, Pennsylvania, October 31 - November 04, 2021. https://doi.org/10.23645/epacomptox.16814986

Hughes, M. Dermal Toxicity. Chapter 11, Introduction to Interdisciplinary Toxicology: From Molecules to Man. Academic Press Incorporated, Orlando, FL, , 141-151, (2020). https://doi.org/10.1016/B978-0-12-813602-7.00011-9

Rogers, K., T. Henson, J. Navratilova, M. Surette, M. Hughes, K. Bradham, A. Stefaniak, A. Knepp, AND L. Bowers. In vitro intestinal toxicity of commercially available spray disinfectant products advertised to contain colloidal silver. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 728:138611, (2020). https://doi.org/10.1016/j.scitotenv.2020.138611

Knudsen, G., A. Trexler, A. Richiards, M. Hughes, AND L. Birnbaum. 2,4,6-Tribromophenol disposition and kinetics in rodents: effects of dose, route, sex, and species. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 169(1):167-179, (2019). https://doi.org/10.1093/toxsci/kfz044

Knudsen, G., A. Trexler, A. Richards, S. Hall, M. Hughes, AND L. Birnbaum. 2,4,6-Tribromophenol disposition and kinetics: effects of dose, route, sex, and species. Society of Toxicology, Baltimore, Maryland, March 10 - 14, 2019.

Knudsen, G., M. Hughes, AND L. Birnbaum. Dermal disposition of Tetrabromobisphenol A Bis(2,3-dibromopropyl) ether (TBBPA-BDBPE) using rat and human skin. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, 301:108-113, (2019). https://doi.org/10.1016/j.toxlet.2018.11.011

Henson, T., J. Navratilova, K. Bradham, K. Rogers, AND M. Hughes. Effect of particle size on the cytotoxicity of zinc oxide nanoparticles in rat and human intestinal cell models. Society of Toxicology Annual Meeting, Baltimore, Maryland, March 10 - 14, 2019.

Henson, T., J. Navratilova, A. Tennant, K. Bradham, K. Rogers, AND M. Hughes. In vitro intestinal toxicity of copper oxide nanoparticles in rat and human cell models. Nanotoxicology. Informa Healthcare, London, Uk, 13(6):795-811, (2019). https://doi.org/10.1080/17435390.2019.1578428