Science Inventory

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Fitzpatrick, H., K. Wallace, T. Freudenrich, M. Mayil Vahanan, AND K. Carstens. Characterization of signaling pathways in in vitro developmental neurotoxicity battery. SOT Conference 2024: A New Approach Method (NAM) to Screen for the Impact of Endogenous Stress on Chemical Toxicity, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25431925

Fitzpatrick, H., K. Wallace, T. Freudenrich, M. Mayil Vahanan, K. Carstens, AND T. Shafer. Characterization of signaling pathways in in vitro developmental neurotoxicity battery (TSfN). Presented at 9th Annual Triangle Society for Neuroscience (TSfN), Durham, NC, April 26, 2024.

Rice, O., Q. Krantz, E. Puckett, P. Evansky, K. Wallace, T. Freudenrich, M. Higuchi, AND T. Shafer. Development Of A Novel in Vitro Method to Study Effects of Volatile Compounds on Neural Activity. Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25407025

Rice, O., Q. Krantz, E. Puckett, P. Evansky, K. Wallace, T. Freudenrich, M. Higuchi, AND T. Shafer. Development of a Novel in Vitro Method to Study Effects of Volatile Compounds on Neural Activity (TSfN). 9th Annual Triangle Society for Neuroscience (TSfN), Durrham, NC, April 26, 2024.

Shafer, T., T. Freudenrich, K. Wallace, M. Mayil Vahanan, AND K. Carstens. Re-testing of false negative compounds in new approach methods (NAMs) for developmental neurotoxicity screening. SOT Conference 2024: A New Approach Method (NAM) to Screen for the Impact of Endogenous Stress on Chemical Toxicity, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25544425

Carstens, K., T. Freudenrich, K. Wallace, S. Choo, A. Carpenter, A. Richard, G. Patlewicz, B. Wetmore, K. Friedman, AND T. Shafer. Evaluation of Per- and Poly fluoroalkyl Substances (PFAS) in vitro toxicity testing for developmental neurotoxicity (SOT 2023). Presented at Society of Toxicology 62nd Annual Meeting and ToxExpo 2023, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22714213

Carstens, K., T. Freudenrich, K. Wallace, S. Choo, A. Carpenter, M. Smeltz, M. Clifton, Matthew Henderson, A. Richard, G. Patlewicz, B. Wetmore, K. Friedman, AND T. Shafer. Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 36(3):402-419, (2023). https://doi.org/10.1021/acs.chemrestox.2c00344

Choo, S., K. Wallace, T. Freudenrich, AND T. Shafer. 03222022-Electrical Impedance for non-destructive, real time measurement of neural cell viability on microelectrode Arrays (Abstract for SOT 22). Society of Toxicology 61st Annual Meeting and ToxExpo 2022, San DIego, California, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19415969

Choo, S., K. Wallace, T. Freudenrich, AND T. Shafer. Electrical Impedance for Non-Destructive, Real Time Measurement of Neural Cell Viability on Microelectrode Arrays. Society of Toxicology 61st Annual Meeting and ToxExpo 2022, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19415969

Carstens, K., T. Freudenrich, K. Wallace, S. Choo, A. Carpenter, A. Richard, G. Patlewicz, B. Wetmore, K. Paul-Friedman, AND T. Shafer. Evaluation of Per- and Poly fluoroalkyl Substances (PFAS) in vitro toxicity testing for developmental neurotoxicity. American Society for Cellular and Computational Toxicology (ASCCT) Conference, Durham, NC, October 19 - 21, 2022. https://doi.org/10.23645/epacomptox.21859527

Gallegos, D., C. Marable, B. Chorley, K. Wallace, T. Freudenrich, AND T. Shafer. Integration of Genomic Data Streams in an In Vitro Network Development Model. Society of Toxicology 2021 Virtual Annual Meeting, Virtual, North Carolina, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.14466096

Kitchin, K., J. Richards, B. Robinette, K. Wallace, Najwa Haykal Coates, B. Castellon, E. Grulke, J. Kou, AND R. Varma. Biochemical Effects of Silver Nanomaterials in Human Hepatocellular Carcinoma (HepG2) Cells. Journal of Nanoscience and Nanotechnology. American Scientific Publishers , VALENCIA, CA, 20(9):5833-5858, (2020). https://doi.org/10.1166/jnn.2020.17858

Kosnik, M., J. Strickland, S. Marvel, D. Wallis, K. Wallace, A. Richard, D. Reif, AND T. Shafer. Concentration-Response Evaluation of ToxCast Compounds for Multivariate Activity Patterns of Neural Network Function. Archives of Toxicology. Springer, New York, NY, 94:469-484, (2020). https://doi.org/10.1007/s00204-019-02636-x

Davila-Montero, S., T. Shafer, K. Wallace, J. Fink, AND A. Mason. Semi-supervised Classification Algorithm using k-means Trajectory Clustering and Support Vector Machine to identify Neuroactive compounds from microelectrode array recordings of cortical neural networks. 2020 Annual Meeting of the Society of Toxicology, Anaheim, California, March 15 - 19, 2020. https://doi.org/10.23645/epacomptox.19104635

Kitchin, K., J. Richards, B. Robinette, K. Wallace, N. Coates, B. Castellon, AND E. Grulke. Biochemical effects of some CeO2, SiO2, and TiO2 nanomaterials in HepG2 cells. CELL BIOLOGY AND TOXICOLOGY. Springer, New York, NY, 2(35):129-145, (2019). https://doi.org/10.1007/s10565-018-9445-x

Kosnick, M., J. Strickland, S. Marvel, D. Wallis, K. Wallace, A. Richard, D. Reif, AND T. Shafer. Concentration-Response Evaluation of ToxCast Compounds for Multivariate Activity Patterns of Neural Network Function (INA 17). International Neurotoxicology Association INA-17, Dusseldorf, N/A, GERMANY, September 29 - October 03, 2019. https://doi.org/10.23645/epacomptox.24530218

Shafer, Tim, J. Brown, B. Lynch, S. Davila-Montero, K. Wallace, AND K. Paul-Friedman. Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 169(2):436-455, (2019). https://doi.org/10.1093/toxsci/kfz052

Kitchin, K., J. Richards, B. Robinette, K. Wallace, N. Coates, B. Castellon, E. Grulke, AND J. Kou. Biochemical effects of some CeO2, SiO2, and TiO2 nanomaterials in HepG2 cells. CELL BIOLOGY AND TOXICOLOGY. Springer, New York, NY, 35(2):129-145, (2019). https://doi.org/10.1007/s10565-018-9445-x

Christopher, F., J. Brown, K. Wallace, J. Wambaugh, I. Shah, AND Tim Shafer. Defining toxicological tipping points in neuronal network development. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 354:81-93, (2018). https://doi.org/10.1016/j.taap.2018.01.017

Millard, D., A. Nicolini, C. Arrowood, J. Bradley, C. Strock, T. Freudenrich, K. Wallace, Tim Shafer, M. Cato, L. Saavedra, D. Haag, T. Feaster, B. Anson, G. Luerman, D. Hess, Y. Shi, J. Li, H. Shi, P. Levesque, M. Kreir, H. Lu, I. Suzuke, A. Odawara, Y. Kanda, D. Herr, R. Roberts, AND J. Pierson. Evaluating the use of microelectrode array technology and cell-based neuronal culture models for proconvulsant risk assessment: progress from the HESI NeuTox Consortium. Safety Pharmacology Society, Washi, District Of Columbia, September 30 - October 03, 2018.

Harrill, J., T. Freudenrich, K. Wallace, K. Ball, Tim Shafer, AND W. Mundy. Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 354(1):24-39, (2018). https://doi.org/10.1016/j.taap.2018.04.001

Frank, C., J. Brown, K. Wallace, W. Mundy, I. Shah, AND Tim Shafer. : Defining toxicological tipping points with microelectrode array recordings of developing neural networks. 2017 Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.

Freudenrich, T., K. Wallace, D. Haag, L. Saavedra, W. Mundy, J. Davila, T. Sudof, M. Wernig, AND Tim Shafer. Comparison of acute effects of neurotoxic compounds in neural networks from rodent and human neurons using microelectrode arrays. Society of Toxicology 2017 Annual Meeting, Baltimore, Maryland, March 12 - 16, 2017.

Strickland, J., K. Wallace, M. Martin, K. Houck, J. Ross, AND Tim Shafer. Concentration-response assessment of ToxCast Phase II compounds on spontaneous neural network activity in vitro. 2017 Society of Toxicology Annual Meeting, Baltimore, MD, March 12 - 16, 2017.

Curry-Chisolm, I., K. Wallace, C. Mack, AND Tim Shafer. Loperamide Inhibits the Spontaneous Activity of Neural Networks. Society of Toxicology 2017 annual meeting, Baltimore, MD, March 12 - 16, 2017.