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Records 1 to
25
of 55 records from author Ashley Murr
2024
Buckalew, A., J. Bailey, A. Murr, AND T. Stoker. Use of the Fischer rat thyroid follicular cell (FRTL-5) iodide uptake assay as a secondary screen of per- and polyfluoroalkyl substances (PFAS) previously identified as potential human sodium-iodide symporter (hNIS) inhibitors. Society of Toxicology, Salt Lake City, UT, March 10 - 14, 2024.
2023
Decrane, R., T. Stoker, A. Murr, J. Ford, AND H. El-Masri. Cross species extrapolation of the disruption of thyroid hormone synthesis by oxyfluorfen using in vitro data, physiologically based pharmacokinetic (PBPK), and thyroid hormone kinetics models. Current Research in Toxicology. Elsevier B.V., Amsterdam, Netherlands, 5:100138, (2023). https://doi.org/10.1016/j.crtox.2023.100138
Stoker, T., J. Wang, A. Murr, J. Bailey, AND A. Buckalew. In Vitro Screening of 149 PFAS Chemicals for Potential Inhibition of the Sodium Iodide Symporter (NIS)#. Society of Toxicology, Nashville, TN, March 19 - 23, 2023.
Decrane, R., T. Stoker, A. Murr, J. Ford, AND H. El-Masri. In vitro to In vivo (IVIVE) and Species Extrapolation for the Disruption of Thyroid Hormone Synthesis by Oxyfluorfen using Physiologically Based Pharmacokinetic (PBPK) and Thyroid Hormones Kinetics Models. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22211938
2022
Hawks, M., T. Stoker, A. Murr, J. Ford, C. Wood, T. Beasley, A. Yackley, D. Jenkins-Hill, AND M. Gilbert. Gestational Exposure To Oxyfluorfen, A Newly-Identified Thyroid Disruptor: Effects In Pregnant Rats And Their Progeny. NC Society of Toxicology Annual Meeting, Durham, NC, October 18, 2022.
2021
Wang, J., A. Richard, A. Murr, A. Buckalew, R. Lougee, Mahmoud A. Shobair, D. Hallinger, S. Laws, AND T. Stoker. Expanded High-Throughput Screening and Chemotype-Enrichment Analysis of the Phase II:e1k ToxCast Library for Human Sodium-Iodide Symporter (NIS) Inhibition. Archives of Toxicology. Springer, New York, NY, 95(5):1723-1737, (2021). https://doi.org/10.1007/s00204-021-03006-2
2020
Buckalew, A., J. Wang, A. Murr, C. Deisenroth, W. Stewart, T. Stoker, AND S. Laws. Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay. Archives of Toxicology. Springer, New York, NY, 94(3):873-885, (2020). https://doi.org/10.1007/s00204-020-02664-y
Devane, D., A. Buckalew, S. Laws, A. Murr, J. Wang, C. Deisenroth, AND T. Stoker. Evaluation of the FRTL-5 Cell Line to Further Confirm Potential Sodium Iodide Symporter (NIS) Inhibitors Identified by High Throughput Screening (HTPS). CHHE 4th Annual Symposium- Exploring Interactions Between the Brain and the Environment, Raleigh, NC, February 20, 2020.
2019
Wang, J., D. Hallinger, A. Murr, A. Buckalew, R. Lougee, A. Richard, S. Laws, AND T. Stoker. High-Throughput Screening and Chemotype-Enrichment Analysis of ToxCast Phase II Chemicals Evaluated for Human Sodium-Iodide Symporter (NIS) Inhibition. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 126:377-386, (2019). https://doi.org/10.1016/j.envint.2019.02.024
2018
Wang, J., D. Hallinger, A. Murr, A. Buckalew, Steve Simmons, S. Laws, AND T. Stoker. High-Throughput Screening and Quantitative Chemical Ranking for Sodium Iodide Symporter Inhibitors in ToxCast Phase 1 Chemical Library. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 52(9):5417-5426, (2018).
Stoker, T., J. Wang, D. Hallinger, A. Murr, A. Buckalew, Steve Simmons, AND S. Laws. High-throughput screening (HTPS) of ToxCast Phase II chemical library for sodium iodide symporter (NIS) Inhibitors. Society of Toxicology, San Antonio, Texas, March 11 - 15, 2018.
Hornung, M., S. Degitz, J. Olker, Joe Korte, J. Denny, S. Laws, T. Stoker, P. Hartig, M. Cardon, D. Hallinger, A. Murr, A. Buckalew, J. Wang, K. Paul-Friedman, AND Steve Simmons. In vitro chemical screening assays to identify thyroid hormone disruptors. SETAC North America Focused Topic Meeting, Durham, NC, April 16 - 18, 2018.
Laws, S., A. Buckalew, J. Wang, D. Hallinger, A. Murr, AND T. Stoker. Use of FRTL-5 Cell Line as a Complementary Assay for Chemicals Identified During High-Throughput Screening as Sodium/Iodide Symporter (NIS) Inhibitors. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
2017
Hallinger, D., A. Murr, A. Buckalew, Steve Simmons, T. Stoker, AND S. Laws. Development of a Screening Approach to Detect Thyroid Disrupting Chemicals that Inhibit the Human Sodium/Iodide Symporter (NIS). TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 40:66-78, (2017).
Wang, J., D. Hallinger, A. Murr, A. Buckalew, T. Stoker, AND S. Laws. Identification of Potential Sodium Iodide Symporter (NIS) Inhibitors in ToxCast Phase1_v2 Chemical Library Using in vitro Radioactive Iodide Uptake (RAIU) Assay. 56th Annual Meeting, Society of Toxicology, Baltimore, MD, March 12 - 16, 2017.
Farmer, W., A. Murr, E. Lachendro, AND T. Stoker. Linking In Vitro Cyclooxygenase Inhibition to Disruption of Ovulation and Decreased PGE2 Production in Gonadotropin-Primed Immature Rats. Triangle Consortium of Reproductive Biology, RTP, NC, February 25, 2017.
2016
Murr, A., D. Hallinger, A. Buckalew, Steve Simmons, T. Stoker, AND S. Laws. DEVELOPMENT OF AN IN VITRO RADIOACTIVE IODIDE UPTAKE ASSAY (RAIU) WITH HUMAN NIS-EXPRESSING HEK293T-EPA CELL LINE. To be Presented at Society of Toxicology, New Orleans, LA, March 13 - 17, 2016.
2015
Narotsky, M., G. Klinefelter, J. Goldman, A. Deangelo, D. Best, T. Mcdonald, L. Strader, A. Murr, J. Suarez, M. George, S. Hunter, AND J. Simmons. Reproductive toxicity of a mixture of regulated drinking-water disinfection by-products in a multigenerational rat bioassay. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 123(6):564-70, (2015).
2014
Simmons, J., G. Klinefelter, J. Goldman, A. Deangelo, D. Best, T. Mcdonald, L. Strader, A. Murr, J. Suarez, M. George, S. Hunter, AND M. Narotsky. Cumulative toxicity of an environmentally relevant mixture of nine regulated disinfection by-products in a multigenerational rat reproductive bioassay. Presented at Society of Toxicology Meeting, PHOENIX, AZ, March 23 - 27, 2014.
2013
Goldman, J., L. Davis, A. Murr, AND R. Cooper. Atrazine-induced elevation or attenuation of the LH surge in the ovariectomized, estrogen-primed female rat: role of adrenal progesterone. REPRODUCTION. BioScientifica Ltd., Bristol, Uk, 146(4):305-14, (2013).
Goldman, J., L. Davis, A. Murr, AND R. Cooper. Bidirectional impact of atrazine-induced elevations in progesterone (P4) on the LH surge in the ovariectomized, estradiol (E2)-primed rat. Presented at Society of Toxicology, March 11 - 14, 2013.
Goldman, J., L. Davis, A. Murr, AND R. Cooper. Bidirectional impact of atrazine-induced elvations in progesterone (P4) on the LH Surge in the ovariectomized (OVX), estradiol (E2)-primed rat. Presented at Society of Toxicology meeting, March 10 - 14, 2013.
Narotsky, M., G. Klinefelter, J. Goldman, D. Best, Anthony McDonald, L. Strader, J. Suarez, A. Murr, I. Thillainadarajah, E. Sidney Hunter, S. Richardson, T. Speth, R. Miltner, J. Pressman, L. Teuschler, G. Rice, V. C. Moser, R. Luebke, AND Jane Ellen Simmons. Comprehensive Assessment of a Chlorinated Drinking Water Concentrate in a Rat Multigenerational Reproductive Toxicity Study##. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 47(18):10653-59, (2013).
Narotsky, M., G. Klinefelter, J. Goldman, D. Best, T. Mcdonald, L. Strader, J. Suarez, A. Murr, I. Thillainadarajah, S. Hunter, S. Richardson, T. Speth, R. Miltner, J. Pressman, L. Teuschler, G. Rice, V. C. Moser, R. Luebke, AND J. Simmons. Comprehensive assessment of a chlorinated drinking water concentrate in a rat multigenerational reproductive toxicity study. ENVIRONMENTAL SCIENCE AND TECHNOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 47(18):10653-1659, (2013).
2010
NAROTSKY, M. G., J. M. GOLDMAN, D. S. BEST, A. E. MURR, G. R. KLINEFELTER, L. F. STRADER, J. D. Saurez, J. G. PRESSMAN, R. J. MILTNER, T. F. SPETH, L. K. TEUSCHLER, G. E. RICE, S. D. RICHARDSON, T. A. MCDONALD, E. S. HUNTER, AND J. E. SIMMONS. Assessment of Reproductive and Developmental Toxicity of Mixtures of Regulated Drinking Water Chlorination By-Products in a Multigenerational Rat Bioassay. Presented at Teratology Society Annual meeting, Louisville, KY, June 26 - 30, 2010.