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Records 1 to
25
of 55 records from author Christopher Mazur
2019
Selano, J., V. Richardson, J. Washington, AND Chris Mazur. Characterization of non-radiolabeled Thyroxine (T4) uptake in cryopreserved rat hepatocyte suspensions: Pharmacokinetic implications for PFOA and PFOS chemical exposure. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 58:230-238, (2019). https://doi.org/10.1016/j.tiv.2019.03.022
2017
Marchitti, S., Chris Mazur, C. Dillingham, S. Rawat, A. Sharma, J. Zastre, AND J. Kenneke. Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 155(1):270-282, (2017).
2016
Richardson, V. AND Chris Mazur. Effects on 2,2’,4,4’-Tetrabromodiphenyl ether (BDE 47) on Thyroxine Metabolism and Transport in Primary Rat and Human Hepatocytes. Society of Toxicology Annual Meeting, New Orleans, LA, March 13 - 17, 2016.
Marchitti, S., Chris Mazur, C. Dillingham, S. Rawat, A. Sharma, J. Zastre, AND J. Kenneke. Interaction of BDE-47 and its Hydroxylated Metabolite 6-OH-BDE-47 with the Human ABC Efflux Transporters P-gp and BCRP: Considerations for Human Exposure and Risk Assessment. SOT 2016, New Orleans, LA, March 13 - 17, 2016.
2015
Richardson, V. AND Chris Mazur. Evaluating Thyroxine Metabolism and Transport in Primary Rat and Human Hepatocytes Following BDE 47 Exposure. ISSX, Orlando, FL, October 18 - 22, 2015.
Mazur, Chris, S. Marchitti, AND J. Zastre. P-glycoprotein Inhibition by the Agricultural Pesticide Propiconazole and Its Hydroxylated Metabolites: Implications for Pesticide-Drug Interactions. TOXICOLOGY LETTERS. Elsevier Science Ltd, New York, NY, 232(1):37-45, (2015).
2014
Mazur, Chris, S. Marchitti, AND J. Zastre. P-glycoprotein Inhibition by the Agricultural Pesticide Propiconazole and Its Hydroxylated Metabolites: Implications for Pesticide-Drug Interactions. Presented at 19th North American ISSX Meeting, San Francisco, CA, October 19 - 23, 2014.
Adams, Lindad, H. El-Masri, J. Wambaugh, T. Tal, N. Baker, Chris Mazur, S. Marchitti, AND J. Kenneke. Physiologically-based Pharmacokinetic(PBPK) Models Application to Screen Environmental Hazards Related to Adverse Outcome Pathways(AOPs). Presented at Society of Toxicology, Phoenix, AZ, March 23 - 27, 2014.
2013
Kenneke, J., S. Marchitti, S. Rawat, D. Chang, Chris Grulke, Chris Mazur, AND Rocky Goldsmith. Chiral Pesticide Pharmacokinetics: A Range of Values. Presented at Society of Toxicology Meeting, San Antonio, TX, March 10 - 14, 2013.
Kenneke, J., S. Marchitti, S. Rawat, Chris Mazur, Q. Cheng, M. Goldsmith, D. Chang, AND C. Grulke. Impact of In Vitro System, Chemical Mistures, and Stereochemistry on the Intrinsic Clearance of 1,2,4-Triazole Fungicides in Human and Rat. Presented at The 19th International Symposium on Microsomes and Drug Oxidations and 12th European ISSX Meeting, Noordwijk aan Zee, NETHERLANDS, June 17 - 21, 2012.
2012
Mazur, Chris, S. Marchitti, M. Dimova, J. Kenneke, A. Lumen, AND J. Fisher. Human and Rat ABC Transporter Efflux of Bisphenol A and Bisphenol A Glucuronide: Interspecies Comparison and Implications for Pharmacokinetic Assessment. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 128(2):317-325, (2012).
2010
MAZUR, C. S., J. F. KENNEKE, J. HESS-WILSON, AND J. C. LIPSCOMB. Differences Between Human and Rat Intestinal and Hepatic Bisphenol-A Glucuronidation and the Influence of Alamethicin on In vitro Kinetic Measurements. DRUG METABOLISM AND DISPOSITION. American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD, 38(12):2232-2238, (2010).
KENNEKE, J. F., D. R. EKMAN, C. S. MAZUR, B. J. Konwick, A. T. Fisk, J. K. AVANTS, AND A. W. GARRISON. Integration of Metabolomics and In vitro Metabolism Assays for Investigating the Stereoselective Transformation of Triadimefon in Rainbow Trout. Chirality. Wiley InterScience, Silver Spring, MD, 22(2):183-192, (2010).
KENNEKE, J. F., C. S. MAZUR, A. W. GARRISON, R. D. Miller, T. SACK, C. BROWN, AND J. K. AVANTS. Stereoselective Metabolism of 1,2,4-Triazole Fungicides in Hepatic Microsomes and Implications for Risk Assessment. Presented at 239th ACS National Meeting & Exposition, San Francisco, CA, March 21 - 25, 2010.
2009
KENNEKE, J. F., C. S. MAZUR, A. W. GARRISON, C. K. CUNNINGHAM, AND R. D. Miller. A Systems Approach to Assessing Risk: The Role of Metabolism Research in Describing and Predicting Exposure. Presented at 19th Annual International Society of Exposure Science Conference, Minneapolis, MN, November 01 - 05, 2009.
MAZUR, C. S., J. F. KENNEKE, M. GOLDSMITH, AND C. BROWN. Contrasting Influence of NADPH and a NADPH-Regenerating System on the Metabolism of Carbonyl-Containing Compounds in Hepatic Microsomes. DRUG METABOLISM AND DISPOSITION. American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD, 37(9):1801-1805, (2009).
KENNEKE, J. F., C. S. MAZUR, W. M. HENDERSON, A. W. GARRISON, S. E. Ritger, T. J. Sack, C. C. Brown, AND J. K. Avants. Kinetics, Mechanisms and Stereoselective Metabolism of 1,2,4-Triazole Fungicides and the Implications for Human Health and Ecological Risk Assessment. Presented at 238th ACS National Meeting & Exposition, Washington, DC, August 16 - 20, 2009.
KENNEKE, J. F., C. S. MAZUR, K. A. Kellock, AND J. P. Overmyer. Mechanistic Approach to Understanding the Toxicity of the Azole Fungicide Triadimefon to a Nontarget Aquatic Insect and Implications for Exposure Assessment. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 43(14):5507-5513, (2009).
2008
MAZUR, C. S. AND J. F. KENNEKE. CROSS-SPECIES COMPARISON OF CONAZOLE FUNGICIDE METABOLITES USING RAT AND RAINBOW TROUT (ONCHLORHYNCHUS MYKISS) HEPATIC MICROSOMES AND PURIFIED HUMAN CYP 3A4. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 42(3):947-954, (2008).
Ritger, S., J. F. KENNEKE, C. S. MAZUR, W. M. HENDERSON, AND J. Fisher. Gender and Species-Mediated Differences in the In Vitro Metabolism of Triadimefon by Rodent Hepatic Microsomes. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.
KENNEKE, J. F., C. S. MAZUR, S. E. Ritger, AND T. SACK. Mechanistic Investigation of the Non-Cytochrome P450 Mediated Metabolism of Triadimefon and Implications for Toxicity. Presented at 4th Pan Pacific Conference on Pesticide Science, Honolulu, HI, June 01 - 05, 2008.
KENNEKE, J. F., C. S. MAZUR, S. E. RITGER, AND T. SACK. Mechanistic Investigation of the Noncytochrome P450-Mediated Metabolism of Triadimefon to Triadimenol in Hepatic Microsomes. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 21(10):1997-2004, (2008).
KENNEKE, J. F., C. S. MAZUR, W. M. HENDERSON, A. W. GARRISON, S. E. RITGER, T. SACK, C. BROWN, AND J. K. AVANTS. XENOBIOTIC METABOLISM RESEARCH AND ITS APPLICATION TO HUMAN AND ECOLOGICAL EXPOSURE AND RISK ASSESSMENT. Presented at Society of Toxicology Annual Meeting, Seattle, WA, March 16 - 20, 2008.
2007
KENNEKE, J. F., W. M. HENDERSON, A. W. GARRISON, S. RITGER, AND C. S. MAZUR. APPLICATION OF ADVANCED IN VITRO TECHNIQUES TO MEASURE, UNDERSTAND AND PREDICT THE KINETICS AND MECHANISMS OF XENOBIOTIC METABOLISM. Presented at International Science Forum on Computational Toxicology, Research Triangle Park, NC, May 21 - 23, 2007.
MAZUR, C. S. AND J. F. KENNEKE. CROSS-SPECIES COMPARISON OF CONAZOLE FUNGICIDE METABOLITES USING RAT AND RAINBOW TROUT (ONCHORHYNCHUS MYKISS) HEPATIC MICROSOMES AND PURIFIED HUMAN CYTOCHROME P450 3A4. Presented at 8th International Society for the Study of Xenobiotics, Sendai, JAPAN, October 09 - 12, 2007.