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Records 1 to
25
of 183 records from author Christy Lambright
2024
Jackson, T., C. Lambright, N. Evans, L. Wehmas, D. Macmillan, J. Bangma, L. Gray, AND J. Conley. Exploring maternal and developmental toxicity of PFO4DA and PFO5DoA using hepatic transcriptomics and serum metabolomics. Society of Toxicology Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.
Conley, J., C. Lambright, N. Evans, J. Bangma, J. Ford, D. Jenkins-Hill, AND L. Gray. Maternal, fetal, and neonatal toxicity of the long-chain, multi-ether PFAS PFO5DoA in the Sprague-Dawley rat. Society of Toxicology 2024 Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.
2023
Conley, J., C. Lambright, N. Evans, A. Dixon, J. Ford, D. Jenkins-Hill, E. Hines, J. McCord, E. Medlock Kakaley, AND L. Gray. Dose addition-based approaches accurately predict maternal and neonatal effects in Sprague-Dawley rats from three different PFAS mixtures studies. Society of Toxicology 2023 Annual Meeting, Nashville, TN, March 19 - 23, 2023.
Conley, J., C. Lambright, N. Evans, A. Farraj, J. Smoot, R. Grindstaff, D. Jenkins-Hill, J. McCord, E. Medlock Kakaley, A. Dixon, E. Hines, AND L. Gray. Dose additive maternal and offspring effects of oral maternal exposure to a mixture of three PFAS (HFPO-DA, NBP2, PFOS) during pregnancy in the Sprague-Dawley rat. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 892:164609, (2023). https://doi.org/10.1016/j.scitotenv.2023.164609
2022
Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, A. Dixon, D. Jenkins-Hill, J. McCord, M. Strynar, J. Ford, AND L. Gray. Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 170:107631, (2022). https://doi.org/10.1016/j.envint.2022.107631
Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, D. Jenkins-Hill, J. McCord, M. Strynar, L. Wehmas, S. Hester, D. Macmillan, AND L. Gray. Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS). ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 160:107056, (2022). https://doi.org/10.1016/j.envint.2021.107056
Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, M. Strynar, AND E. Gray. Developmental toxicity of emerging perfluoroalkyl ether carboxylic acids of varying chain length: PFMOAA, PFO4DA and PFO5DoA. Society for Birth Defects Research and Prevention, Raleigh, NC, June 25 - 29, 2022.
Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, J. Ford, J. McCord, M. Strynar, AND E. Gray. Evaluation of dose additive effects of combined oral maternal exposure to PFOA and PFOS during pregnancy in the Sprague-Dawley rat. 2022 Society of Toxicology Annual Meeting, San Diego, CA, March 27 - 31, 2022.
Gray, E., J. Conley, C. Lambright, AND J. FURR. In utero exposure to a mixture of the perfluoroalkyl-isopropyl pesticide pyrifluquinazon with dibutyl phthalate cumulatively disrupts male rat reproductive development via different mechanisms of action. Birth Defects Research and Prevention BDRP 2022, VANCOUVER, BRITISH COLOMBIA, CANADA, June 25 - 29, 2022.
Gray, E., J. Conley, C. Lambright, AND J. Furr. In utero exposure to a mixture of the perfluoroalkylisopropyl pesticide pyrifluquinazon with dibutyl phthalatecumulatively disrupts male rat reproductive development via different mechanisms of action. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(2):234-247, (2022). https://doi.org/10.1093/toxsci/kfac059
2021
Conley, J., C. Lambright, N. Evans, M. Cardon, E. MedlockKakaley, V. Wilson, AND E. Gray. A mixture of 15 phthalates and pesticides below individual chemical No Observed Adverse Effect Levels (NOAELs) produces reproductive tract malformations in the male rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 156(106615):1, (2021). https://doi.org/10.1016/J.ENVINT.2021.106615
MedlockKakaley, E., M. Cardon, N. Evans, C. Lambright, B. Blackwell, R. Hofer, L. Hubbard, P. Bradley, J. Conley, E. Gray, AND D. Kolpin. Biological Activity in US Food Processing Plant Effluent. SETAC Europe Annual Meeting (Virtual), Durham-Virtual, NC, May 03 - 06, 2021.
Gray, E., C. Lambright, N. Evans, V. Wilson, B. Hannas, P. Foster, AND J. Conley. Biological Relevance of Phthalate-Induced Disruption of Fetal Testis Hormones and Gene Expression: Key Events in a Novel AOP. Society of Toxicology - Virtual, NA, Virtual, March 12 - 26, 2021.
Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, A. Dixon, E. Hines, AND E. Gray. Dose additive developmental toxicity of a mixture of three PFAS (HFPO-DA, NBP2, PFOS) in the Sprague-Dawley rat. 2021 Society of Toxicology Annual Meeting-Virtual, NA, Virtual, March 12 - 26, 2021.
MacMillan, D., N. Evans, E. Gray, C. Lambright, AND J. Conley. Exploring Potential Differences in Developmental Toxicology of Per- and Polyfluoroalkyl Substances (PFAS) Through Targeted Metabolomics. American Society for Mass Spectrometry Conference, Philadelphia, Pennsylvania, October 30 - November 04, 2021. https://doi.org/10.23645/epacomptox.16840390
Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, AND E. Gray. Exposure to a mixture of PFOA and PFOS during pregnancy produces cumulative effects on F1 bodyweight, liver weight, and survival in the Sprague-Dawley rat. FLUOROS Global 2021, Providence, RI, October 03 - 07, 2021.
Gray, E., C. Lambright, J. Conley, N. Evans, J. Furr, B. Hannas, V. Wilson, H. Sampson, AND P. Foster. Genomic and Hormonal Biomarkers of Phthalate-Induced Male Rat Reproductive Developmental Toxicity Part II: A Targeted RT-qPCR Array Approach that Defines a Unique Adverse Outcome Pathway. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 182(2):195-214, (2021). https://doi.org/10.1093/toxsci/kfab053
Conley, J., C. Lambright, N. Evans, J. McCord, M. Strynar, D. Hill, E. MedlockKakaley, V. Wilson, AND E. Gray. Hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) alters maternal and fetal glucose and lipid metabolism and produces neonatal mortality, low birthweight and hepatomegaly in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 146:106204, (2021). https://doi.org/10.1016/j.envint.2020.106204
2020
Gray, L., C. Lambright, N. Evans, M. Cardon, E. Medlock Kakaley, V. Wilson, AND J. Conley. Development of and AOP network for the developmental effects of exposure to PFAS. Virtual -Society of Toxicology Annual Meeting 2020, Anaheim, CA, March 15 - 20, 2020.
Lambright, C., N. Evans, M. Cardon, E. Medlock Kakaley, V. Wilson, J. Conley, AND L. Gray. Gene expression changes in maternal, fetal, and neonatal tissues from exposure to hexafluoropropylene oxide-dimer acid (HFPO-DA, GenX). Society of Toxicology Annual Meeting-Virtual -Webinar, Anaheim, CA, April 30, 2020.
Gray, L., J. Furr, C. Lambright, N. Evans, P. Hartig, M. Cardon, V. Wilson, A. Hotchkiss, AND J. Conley. Quantification of uncertainties in extrapolating from in vitro androgen receptor (AR) antagonism to in vivo Hershberger Assay endpoints and adverse reproductive development in male rats. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 176(2):297-311, (2020). https://doi.org/10.1093/toxsci/kfaa067
2019
Gray, E., J. Furr, J. Conley, C. Lambright, N. Evans, M. Cardon, V. Wilson, P. Foster, AND P. Hartig. A Conflicted Tale of Two Novel AR Antagonists In vitro and In vivo: Pyrifluquinazon versus Bisphenol C. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, , 632-643, (2019). https://doi.org/10.1093/toxsci/kfz010
Conley, J., C. Lambright, N. Evans, M. Strynar, J. McCord, B. McIntyre, G. Tavlos, M. Cardon, E. Medlock Kakaley, P. Hartig, V. Wilson, AND L. Gray. Adverse effects of oral gestational exposure to hexafluoropropylene oxide dimer acid (GenX) in the Sprague-Dawley rat- Presentation. Society of Toxicology, Baltimore, MD, March 10 - 14, 2019.
Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, V. Wilson, AND L. Gray. Adverse effects of oral gestational exposure to hexafluoropropylene oxide dimer acid (GenX) in the Sprague-Dawley rat. SETAC. Teratology Society Annual Meeting, San Diego, CA, June 22 - 26, 2019.
Conley, J., C. Lambright, N. Evans, M. Strynar, J. McCord, B. McIntyre, G. Travlos, M. Cardon, E. MedlockKakaley, P. Hartig, V. Wilson, AND E. Gray. Adverse maternal, fetal, and postnatal effects of Hexafluoropropylene oxide dimer acid (GenX) from oral gestational exposure in Sprague Dawley rats. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, , 1-13, (2019). https://doi.org/10.1289/EHP4372