Science Inventory

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Maloney, E., D. Villeneuve, K. Jensen, B. Blackwell, M. Kahl, S. Poole, K. Vitense, D. Feifarek, G. Patlewicz, Kenneth Dean, C. Tilton, E. Randolph, J. Cavallin, C. Lalone, D. Blatz, C. Schaupp, AND G. Ankley. Evaluation of Complex Mixture Toxicity in the Milwaukee Estuary (WI, USA) Using Whole-Mixture and Component-Based Evaluation Methods. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 42(6):1229-1256, (2023). https://doi.org/10.1002/etc.5571

Villeneuve, D., B. Blackwell, J. Cavallin, J. Collins, J. Hoang, R. Hofer, K. Houck, K. Jensen, M. Kahl, R. Kutsi, A. Opseth, K. Santana Rodriguez, C. Schaupp, E. Stacy, AND G. Ankley. In vivo effects of four per- and polyfluoroalkyl substances identified as estrogenic via in vitro screening. Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.24749445

Villeneuve, D., B. Blackwell, J. Cavallin, J. Collins, J. Hoang, R. Hofer, K. Houck, K. Jensen, M. Kahl, R. Kutsi, A. Opseth, K. Santana Rodriguez, C. Schaupp, E. Stacy, AND G. Ankley. Verification of In Vivo Estrogenic Activity for Four Per- and Polyfluoroalkyl Substances (PFAS) Identified as Estrogen Receptor Agonists via New Approach Methodologies. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 57(9):3794-3803, (2023). https://doi.org/10.1021/acs.est.2c09315

Collins, J., J. Cavallin, A. Cole, K. Jensen, M. Kahl, K. Santana Rodriguez, A. Kittelson, AND Dan Villeneuve. Applying EcoToxChips to Identify Potential Gene Expression Markers of Exposure to Glucocorticoid Receptor Agonists. SETAC North America, Pittsburgh, PA, November 13 - 17, 2022. https://doi.org/10.23645/epacomptox.21424434

Villeneuve, D., B. Blackwell, C. Blanksma, J. Cavallin, W. Cheng, R. Conolly, K. Conrow, D. Feifarek, L. Heinis, K. Jensen, M. Kahl, R. Milsk, S. Poole, E. Randolph, T. Saari, K. Watanabe, AND G. Ankley. Case Study in 21st-Century Ecotoxicology: Using In Vitro Aromatase Inhibition Data to Predict Reproductive Outcomes in Fish In Vivo. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 42(1):100-116, (2023). https://doi.org/10.1002/etc.5504

Blackwell, B., G. Ankley, A. Biales, J. Cavallin, A. Cole, T. Collette, D. Ekman, R. Hofer, W. Huang, K. Jensen, M. Kahl, A. Kittelson, S. Romano, M. See, Q. Teng, C. Tilton, AND D. Villeneuve. Effects of Metformin and its Metabolite Guanylurea on Fathead Minnow (Pimephales promelas) Reproduction (FY22 Manuscript). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 41(11):2708-2720, (2022). https://doi.org/10.1002/etc.5450

Santana Rodriguez, K., Dan Villeneuve, J. Cavallin, B. Blackwell, J. Hoang, R. Hofer, K. Jensen, M. Kahl, R. Kutsi, E. Stacy, M. Morshead, AND G. Ankley. Examining Effects of an Estrogenic PFAS, 1H,1H,8H,8H-Perfluorooctane-1,8-diol (FC8-diol), Using the Fathead Minnow Ecotoxchip. SETAC, Pittsburgh, PA, November 13 - 17, 2022. https://doi.org/10.23645/epacomptox.21429543

Garcia-Reyero, N., M. Arick II, A. Woolard, M. Wilbanks, J. Mylroie, K. Jensen, M. Kahl, D. Feifarek, S. Poole, E. Randolph, J. Cavallin, B. Blackwell, Dan Villeneuve, G. Ankley, AND E. Perkins. Male fathead minnow transcriptomes and associated chemical analytes in the Milwaukee estuary system. Scientific Data. Springer Nature, New York, NY, 9:476, (2022). https://doi.org/10.1038/s41597-022-01553-6

Doering, J., Dan Villeneuve, C. Tilton, A. Kittelson, B. Blackwell, M. Kahl, K. Jensen, S. Poole, J. Cavallin, A. Cole, K. Dean, C. LaLone, AND G. Ankley. Assessing effects of aromatase inhibition on fishes with group-synchronous oocyte development using western mosquitofish (Gambusia affinis) as a model. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 232:105741, (2021). https://doi.org/10.1016/j.aquatox.2020.105741

Villeneuve, Dan, B. Blackwell, J. Cavallin, W. Cheng, R. Conolly, D. Feifarek, K. Jensen, M. Kahl, R. Milsk, S. Poole, E. Randolph, T. Saari, AND G. Ankley. Case study in 21st century ecotoxicology: Using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 40(4):1155-1170, (2021). https://doi.org/10.1002/etc.4968

Maloney, E., G. Ankley, B. Blackwell, J. Cavallin, D. Feifarek, M. Kahl, S. Poole, E. Randolph, K. Jensen, C. LaLone, D. Blatz, C. Schaupp, AND Dan Villeneuve. Evaluation of Complex Mixture Toxicity: An Effects-Driven Analysis in the Milwaukee Estuary Area of Concern (Milwaukee, WI). SETAC North America 42nd Annual meeting, Portland, OR, November 14 - 18, 2021. https://doi.org/10.23645/epacomptox.17100254

Harvey, J., W. Cascio, J. Graff, M. Hoopes, L. Jarrell, S. Ayvazian, L. Coiro, R. Hockett, M. Kahl, C. Lilavois, AND D. Brumbaugh. Maintaining Compliance through Technology during a Pandemic: Virtual Facility Inspections and Program Reviews. 2021 American Association for Laboratory Animal Science (AALAS) National Meeting, Virtual, October 17 - 21, 2021.

Ankley, G., J. Berninger, B. Blackwell, J. Cavallin, Tim Collette, D. Ekman, K. Fay, D. Feifarek, K. Jensen, M. Kahl, J. Mosley, S. Poole, E. Randolph, D. Rearick, A. Schroeder, J. Swintek, AND Dan Villeneuve. Pathway-based approaches for assessing biological hazards of complex mixtures of contaminants: A case study in the Maumee River. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, 40(4):1098–1122, (2021). https://doi.org/10.1002/etc.4949

Cavallin, J., G. Ankley, B. Blackwell, J. Hoang, R. Hofer, K. Houck, K. Jensen, M. Kahl, R. Kutsi, A. Opseth, K. Santana Rodriguez, E. Stacy, AND Dan Villeneuve. Verification of In Vivo Estrogenic Activity for Four Polyfluoroalkyl Substances (PFAS) Identified as Estrogen Receptor Agonists in High-Throughput Screening. SETAC North America 42nd Annual meeting, Portland, OR, November 14 - 18, 2021. https://doi.org/10.23645/epacomptox.17064230

Maloney, E., G. Ankley, K. Vitense, B. Blackwell, J. Cavallin, D. Feifarek, K. Jensen, M. Kahl, S. Poole, E. Randolph, AND Dan Villeneuve. Weight-of-evidence prioritization of organic ontaminants detected in the Milwaukee Estuary Area of Concern (Milwaukee, WI). Emerging Contaminants in the Environment Virtual Conference, Duluth, MN, April 27 - 28, 2021. https://doi.org/10.23645/epacomptox.16619752

Ankley, G., B. Blackwell, J. Cavallin, J. Doering, D. Feifarek, K. Jensen, M. Kahl, C. Lalone, S. Poole, E. Randolph, T. Saari, AND D. Villeneuve. Adverse outcome pathway network-based assessment of the interactive effects of an androgen receptor agonist and an aromatase inhibitor on fish endocrine function. AQUATIC TOXICOLOGY. Elsevier Science Ltd, New York, NY, 39(4):913-922, (2020). https://doi.org/10.1073/pnas

Santana Rodriguez, K., Dan Villeneuve, K. Jensen, M. Kahl, J. Doering, J. Cavallin, A. Cole, A. Kittleson, S. Poole, K. Dean, C. Jenson, AND G. Ankley. Application of bioactivity-based monitoring to evaluate remediation effectiveness – a case study at Erie Pier Ponds, Duluth, MN. SETAC North America, Fort Worth, TX, November 15 - 19, 2020.

Blackwell, B., G. Ankley, J. Cavallin, A. Cole, A. Kittleson, M. Kahl, K. Jensen, C. Tilton, AND Dan Villeneuve. Effects of metformin and its metabolite guanylurea on fathead minnow (Pimephales promelas) reproduction. SETAC North America, Fort Worth, TX, November 15 - 19, 2020. https://doi.org/10.23645/epacomptox.13120208

Maloney, E., G. Ankley, B. Blackwell, J. Cavallin, D. Feifarek, K. Jensen, M. Kahl, S. Poole, E. Randolph, AND Dan Villeneuve. Effects–Based Monitoring Under the Great Lakes Restoration Initiative: Evaluation of Spatial and Temporal Patterns in the Milwaukee Estuary. SETAC North America, Fort Worth, TX, November 15 - 19, 2020. https://doi.org/10.23645/epacomptox.13122380

Doering, J., G. Ankley, B. Blackwell, J. Cavallin, A. Cole, K. Dean, K. Fay, D. Feifarek, K. Jensen, M. Kahl, A. Kittelson, C. Lalone, S. Poole, E. Randolph, C. Tilton, AND D. Villeneuve. A cross-species model for predicting reproductive dysfunction in fishes exposed to aromatase inhibiting chemicals. Twin Ports Early-Career Researchers Symposium, Duluth, MN, March 28, 2019.

Doering, J., D. Villeneuve, B. Blackwell, J. Cavallin, A. Cole, K. Dean, K. Faye, D. Feifarek, K. Jensen, M. Kahl, A. Kittelson, C. Lalone, S. Poole, E. Randolph, C. Tilton, AND G. Ankley. Aromatase inhibition in fishes with group-synchronous oocyte development: The importance of reproductive traits. SETAC North America, Toronto, ON, CANADA, November 03 - 07, 2019.

Doering, J., G. Ankley, B. Blackwell, J. Cavallin, A. Cole, K. Dean, K. Fay, D. Feifarek, K. Jensen, M. Kahl, A. Kittelson, C. LaLone, S. Poole, E. Randolph, C. Tilton, AND Dan Villeneuve. Cross-species Applicability of a quantitative AOP describing inhibition of aromatase activity leading to reproductive dysfunction in fishes. SETAC Europe, Helsinki, N/A, FINLAND, May 26 - 30, 2019.

Tilton, C., C. Blanksma, J. Cavallin, G. Ankley, J. Swintek, K. Jensen, M. Kahl, AND D. Villeneuve. Development of a juvenile fathead minnow fin regeneration assay for use in evaluating chemical involvement in fin regeneration impairment. St. Louis River Summit, Superior, WI, March 05 - 06, 2019.

Doering, J., Dan Villeneuve, K. Fay, E. Randolph, K. Jensen, M. Kahl, C. LaLone, AND G. Ankley. Differential sensitivity to in vitro inhibition of cytochrome P450 aromatase (CYP19) activity among 18 freshwater fishes. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 170(2):394-403, (2019). https://doi.org/10.5061/dryad.nn94830

Doering, J., D. Villeneuve, S. Poole, B. Blackwell, K. Jensen, M. Kahl, A. Kittelson, D. Feifarek, C. Tilton, C. Lalone, AND G. Ankley. Quantitative response-response relationships linking aromatase inhibition to decreased fecunditiy are conserved across three fishes with asynchronous oocyte development. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 53(17):10470-10478, (2019). https://doi.org/10.1021/acs.est.9b02606