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Records 1 to 25 of 140 records from author Barbara Abbott

2019
Baker, N., N. Sipes, J. Franzosa, D. Belair, B. Abbott, R. Judson, AND T. Knudsen. Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature. Birth Defects Research. John Wiley & Sons, Inc., Hoboken, NJ, , 1-21, (2019). https://doi.org/10.1002/bdr2.1581
Abbott, B. Embryonic midfacial palatal organ culture methods in developmental toxicology. Developmental Toxicology: Meethods and Protocols.. Humana Press Incorporated, Totowa, NJ, , 93-105, (2019). https://doi.org/10.1007/978-1-4939-9182-2
2018
Belair, D., C. Wolf, S. Moorefield, C. Wood, C. Becker, AND B. Abbott. A Three-Dimensional Organoid Culture Model to Assess the Influence of Chemicals on Morphogenetic Fusion. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 166(2):394-408, (2018). https://doi.org/10.1093/toxsci/kfy207
Abbott, B., D. Belair, Cynthiaj Wolf, K. Das, C. Wood, C. Becker, AND S. Moorefield. An Engineered Organoid Culture Model That Incorporates Human Mesenchymal and Epithelial Cells to Model Palatal Fusion. Teratology Society Annual Meeting, Clearwater, Florida, June 23 - 28, 2018.
Wolf, Cynthiaj, D. Belair, C. Becker, K. Das, Judy Schmid, AND B. Abbott. Development of an organotypic stem cell model for the study of human embryonic palatal fusion. BIRTH DEFECTS RESEARCH PART B: DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, , 1322-1334, (2018). https://doi.org/10.1002/bdr2.1394
Belair, D., Cynthiaj Wolf, C. Wood, S. Moorefield, C. Becker, H. Ren, A. Fisher, AND B. Abbott. Effects of chemicals and pathway inhibitors on a human in vitro model of secondary palatal fusion. Society of Toxicology 57th Annual Meeting, San Antonio, Texas, March 11 - 15, 2018.
2017
Moorefield, S., D. Belair, AND B. Abbott. Disruption of epithelial cell migration as a potential mechanism of cleft palate induction. NCSOT, RTP, NC, October 30, 2017.
Belair, D. AND B. Abbott. Engineering epithelial-stromal interactions in vitro for toxicology assessment. TOXICOLOGY. Elsevier Science Ltd, New York, NY, , 93-107, (2017).
Belair, D., Cynthiaj Wolf, C. Wood, H. Ren, R. Grindstaff, W. Padgett, A. Swank, D. MacMillan, A. Fisher, W. Winnik, AND B. Abbott. Engineering human cell spheroids to model embryonic tissue fusion in vitro. PLOS ONE . Public Library of Science, San Francisco, CA, 12(9):e0184155, (2017).
Rosen, M., K. Das, J. Rooney, B. Abbott, C. Lau, AND C. Corton. PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 387:95-107, (2017).
Das, K., C. Wood, M. Lin, A. Starkov, C. Lau, K. Wallace, C. Corton, AND B. Abbott. Perfluoroalky acids-induced liver steatosis: Effects on genes controlling lipid homeostasis. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 378:32-52, (2017).
2016
Abbott, B., D. Belair, Cynthiaj Wolf, K. Das, C. Wood, W. Winnik, A. Fisher, R. Grindstaff, A. Swank, H. Ren, AND W. Padgett. Case Study: Organotypic human in vitro models of embryonic morphogenetic fusion. BoSC Meeting, RTP, NC, November 16 - 17, 2016.
Wolf, Cynthiaj, C. Becker, K. Das, A. Watkins, D. Belair, AND B. Abbott. Development of a 3D co-culture model using human stem cells for studying embryonic palatal fusion. Teratology Society Annual Meeting, San Antonio, TX, June 25 - 29, 2016.
Belair, D., Cynthiaj Wolf, K. Das, A. Watkins, AND B. Abbott. Organotypic three-dimensional culture model of mesenchymal and epithelial cells to examine tissue fusion events. Presented at Society of Toxicology Meeting, New Orleans, LA, March 13 - 17, 2016.
2015
Baker, N., N. Sipes, C. Grulke, M. Leung, J. A, B. Abbott, R. Judson, AND T. Knudsen. Chemical and HTS Profiling of 63 Cleft Palate Teratogens from ToxCast (FutureTox III). Presented at FutureTox III, Arlington, VA, November 19 - 20, 2015. https://doi.org/10.23645/epacomptox.5189362
Abbott, B. Developmental Toxicity. Chapter 8, Jamie C. DeWitt (ed.), Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances. Springer Basel AG, Basel, Switzerland, , 203-218, (2015).
Oshida, K., N. Vasani, W. Ward, R. Thomas, D. Applegate, Mitch Rosen, B. Abbott, C. Lau, G. Guo, L. Aleksunes, C. Klaassen, AND C. Corton. Identification of Modulators of the Nuclear Receptor Peroxisome Proliferator-Activated Receptor α (PPARα) in a Mouse Liver Gene Expression Compendium. PLOS ONE . Public Library of Science, San Francisco, CA, 10(2):e0112655, (2015).
Watkins, A., C. Wood, M. Lin, AND B. Abbott. The Effects of Perfluorinated Chemicals on Adipoctye Differentiation In Vitro. Molecular and Cellular Endocrinology. ELSEVIER, AMSTERDAM, Holland, 400(1):90-101, (2015).
2014
Wolf, Cynthiaj, M. Fang, H. Stapleton, AND B. Abbott. Activation of human peroxisome-activated receptor-gamma (PPARy) by house dust extracts. Presented at Teratology Society Annual Meeting, Bellevue, WA, June 28 - July 02, 2014.
Diggs, D., J. Norwood, C. Wood, M. Lin, J. Rogers, C. Lau, AND B. Abbott. An Evaluation of Gestational Exposure to Perfluorooctanoic Acid (PFOA): Effects on Body Composition and Physiological Factors. Presented at Society of Toxicology, Phoenix, AZ, March 23 - 27, 2014.
Wolf, Cynthiaj, C. Ryder, C. Lau, AND B. Abbott. Evaluating the additivity of perfluoroalkyl acids (PFAAs) in binary combinations on peroxisome proliferator-activated receptor-a(PPARa) activation. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 316:43-54, (2014).
2013
Corton, C., N. Vasani, Mitch Rosen, B. Abbott, C. Lau, W. Ward, R. Thomas, D. Applegate, AND K. Oshida. A Global Genomic Screening Strategy Reveals Genetic and Chemical Activators ofPeroxisome Proliferator-Activated Receptor alpha (PPARalpha). Presented at Society of Toxicology Annual Meeting, March 10 - 14, 2013.
Watkins, A., C. Wood, M. Lin, AND B. Abbott. Effects of perfluorinated chemicals on adipocyte development. Presented at Teratology Society Annual meeting, Tucson, AZ, June 22 - 26, 2013.
Rosen, Mitch, K. Das, C. Wood, Cynthiaj Wolf, B. Abbott, AND C. Lau. Evaluation of Perfluoroalkyl Acid Activity Using Primary Mouse and Human Hepatocytes. In Proceedings, Society of Toxicology, San Francisco, CA, March 10 - 15, 2012. Toxicology, 129-37, (2013).
Wolf, Cynthiaj, C. Rider, C. Lau, AND B. Abbott. Evaluation of additivity of binary mixtures of perfluoroalkyl acids (PFAAs) on peroxisome proliferator-activated receptor-alpha (PPARa) activation in vitro. Presented at Society of Toxicology, March 10 - 14, 2013.