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Wehmas, L. Application of Early Molecular Measurements to Develop Points of Departure for Risk Assessment. SOT, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25438726

Wehmas, L. Development of Transcriptomic Points of Departure for EPA’s Transcriptomic Assessment Product (ETAP). AWMA, Raleigh, NC, January 23, 2024. https://doi.org/10.23645/epacomptox.25121804

Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, Kristina Chialton, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, AND W. Casey. EPA Transcriptomic Assessment Product (ETAP) for Perfluoro-3-Methoxypropanoic Acid. U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-24/066, 2024. https://doi.org/10.23645/epacomptox.25352962

Jackson, T., C. Lambright, N. Evans, L. Wehmas, D. Macmillan, J. Bangma, L. Gray, AND J. Conley. Exploring maternal and developmental toxicity of PFO4DA and PFO5DoA using hepatic transcriptomics and serum metabolomics. Society of Toxicology Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.

Chang, D., J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, G. Patlewicz, R. Thomas, L. Wehmas, K. Vitense, S. Auerbach, W. Casey, R. Sams, S. Hunter, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/084, 2024. https://doi.org/10.23645/epacomptox.25365550

Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, K. Thayer, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, W. Casey, R. Sams, S. Hunter, W. Cascio, K. Holt, S. Jones, R. Subramaniam, G. Rice, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Standard Methods for Development of EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/083, 2024. https://doi.org/10.23645/epacomptox.25365496

Waterbury, C., J. Conley, L. Gray, AND L. Wehmas. Targeted RNA-sequencing of testes from fetal rats exposed to dicyclohexyl phthalate informs potency and adverse outcome pathway development (SOT 24). Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25475944

Wehmas, L. Using transcriptomics to understand the risk and toxicity of PFAS chemicals. Center for PFAS and Cancer (CPAC) Joint Virtual Symposium, Washington, DC, March 06 - 08, 2024. https://doi.org/10.23645/epacomptox.25365592

Renyer, A., K. Ravindra, B. Wetmore, J. Ford, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Dose Response, Dosimetric, and Metabolic Evaluations of Replacement PFAS Perfluoro-(2,5,8-trimethyl-3,6,9-trioxadodecanoic) Acid (HFPO-TeA). Toxics. MDPI, Basel, Switzerland, 11(12):951, (2023). https://doi.org/10.3390/toxics11120951

Renyer, A., B. Payne, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Dosimetry and Potential Bioaccumulation of a GenX Oligomer HFPO-TeA. Presented at SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22272334

Wehmas, L. EPA Transcriptomic Assessment Product Study Overview. BOSC, Virtual, NC, July 11 - 12, 2023. https://doi.org/10.23645/epacomptox.23657145

Wehmas, L., K. Flynn, M. Hazemi, S. Hester, AND Dan Villeneuve. Gene Expression-Based Dose Response Analysis of Short-Term Rat and Fathead Minnow Exposures to Two Metal Sulfates Indicates Chronic Chemical Potency. SETAC, Louisville, KY, November 12 - 16, 2023. https://doi.org/10.23645/epacomptox.24794595

Brennan, A., S. Shaut, A. Renyer, R. Payne, J. Ford, M. Devito, M. Hughes, L. Wehmas, AND D. Macmillan. Identification of Biotransformation Products (BPs) in Rats Exposed to 6:1 Fluorotelomer Alcohol (6:1 FTOH). SETAC, Louisville, KY, November 12 - 16, 2023. https://doi.org/10.23645/epacomptox.24526438

Martin, R., M. Hazemi, K. Flynn, D. Villeneuve, AND L. Wehmas. Short-Term Transcriptomic Points of Departure Are Consistent with Chronic Points of Departure for Three Organophosphate Pesticides across Mouse and Fathead Minnow. Toxics. MDPI, Basel, Switzerland, 11(10):820, (2023). https://doi.org/10.3390/toxics11100820

Martin, R., S. Hester, M. Hazemi, K. Flynn, Dan Villeneuve, AND L. Wehmas. Short-term transcriptomic points-of-departure are consistent with their chronic points-of departure for three organophosphate pesticides. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22596343

Wehmas, L. AND S. Hester. Toxicogenomic analysis of >25-year-old archival tissue samples indicate metal sulfate mode of action and potency. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22630594

Wehmas, L. Transcriptomics in Dose Response Assessment Literature Review. BOSC, Virtual, NC, July 11 - 12, 2023. https://doi.org/10.23645/epacomptox.23657139

Johnson, K., S. Auerbach, T. Stevens, T. Barton-Maclaren, E. Costa, R. Currie, D. Dalmas Wilk, S. Haq, J. Rager, A. Reardon, L. Wehmas, A. Williams, J. O'Brien, C. Yauk, J. LaRocca, AND S. Pettit. A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 190(2):127-132, (2022). https://doi.org/10.1093/toxsci/kfac097

Mills, M., E. Bruce, M. Huang, J. Crothers, O. Hyrien, C. Oura, L. Blake, A. Brown Jordan, S. Hester, L. Wehmas, B. Mari, P. Barby, C. Lacoux, J. Fassy, P. Vial, C. Vial, J. Martinez, O. Oladipo, B. Inuwa, I. Shittu, C. Meseko, R. Chammas, C. Santos, T. Dionísio, T. Garbieri, V. Parisi, M. Mendes-Correa, A. dePaula, C. Romano, L. Góes, P. Minoprio, A. Campos, M. Cunha, A. Vilela, T. Nyirenda, R. Mkakosya, A. Muula, R. Dumm, R. Harris, C. Mitchell, S. Pettit, J. Botten, AND K. Jerome. An international, interlaboratory ring trial confirms the feasibility of an extraction-less “direct” RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples. PLOS ONE . Public Library of Science, San Francisco, CA, 17(1):e0261853, (2022). https://doi.org/10.1371/journal.pone.0261853

Cannizzo, M., C. Wood, S. Hester, AND L. Wehmas. Case study: Targeted RNA-sequencing of aged formalin-fixed paraffin-embedded samples for understanding chemical mode of action. Toxicology Reports. Elsevier B.V., Amsterdam, Netherlands, 9:883-894, (2022). https://doi.org/10.1016/j.toxrep.2022.04.012

Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, D. Jenkins-Hill, J. McCord, M. Strynar, L. Wehmas, S. Hester, D. Macmillan, AND L. Gray. Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS). ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 160:107056, (2022). https://doi.org/10.1016/j.envint.2021.107056

MacMillan, D., A. Renyer, M. Smeltz, M. Phillips, K. Ravindra, M. Devito, M. Hughes, L. Wehmas, AND B. Wetmore. Evaluations of in vivo and in vitro dosimetry and metabolic biotransformation of the hexafluoropropylene oxide homologue HFPO-TeA, an emerging per-and polyfluoroalkyl substance (PFAS). SETAC, Pittsburgh, PA, November 13 - 17, 2022. https://doi.org/10.23645/epacomptox.21552594

Brennan, A., L. Albrecht, M. Phillips, J. Ford, B. Wetmore, L. Wehmas, M. Hughes, AND M. Devito. In-vivo and in-vitro quantitation and stability of fluorotelomer compounds in rat and human plasma to inform toxicity. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19376039

Renyer, A., D. MacMillan, M. Devito, M. Hughes, AND L. Wehmas. Internal Dose and In-Life Results of Perfluoro-2,5,8-trimethyl-3,6,9-trioxadodecanoic acid Exposure from Short Term Dosing Studies in Rats. ASMS Conference on Mass Spectrometry and Allied Topics, Minneapolis, MN, June 05 - 09, 2022. https://doi.org/10.23645/epacomptox.19890808

Renyer, A., D. MacMillan, M. Devito, M. Hughes, AND L. Wehmas. Internal dose of perfluoro-3-methoxypropanoic acid in rat plasma and in-life effects from short term dosing studies. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19341683