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25
of 81 records from author Justin Conley
2024
Jackson, T., C. Lambright, N. Evans, L. Wehmas, D. Macmillan, J. Bangma, L. Gray, AND J. Conley. Exploring maternal and developmental toxicity of PFO4DA and PFO5DoA using hepatic transcriptomics and serum metabolomics. Society of Toxicology Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.
Conley, J., C. Lambright, N. Evans, J. Bangma, J. Ford, D. Jenkins-Hill, AND L. Gray. Maternal, fetal, and neonatal toxicity of the long-chain, multi-ether PFAS PFO5DoA in the Sprague-Dawley rat. Society of Toxicology 2024 Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.
Waterbury, C., J. Conley, L. Gray, AND L. Wehmas. Targeted RNA-sequencing of testes from fetal rats exposed to dicyclohexyl phthalate informs potency and adverse outcome pathway development (SOT 24). Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25475944
2023
Macmillan, D., J. Ford, L. Gray, AND J. Conley. Comparative Metabolomics of Short-term Maternal Gestational Exposure of Rats to Emerging Perfluoroalkyl Ether Carboxylic Acids. Dioxin 2023, Maastricht, NETHERLANDS, September 10 - 14, 2023. https://doi.org/10.23645/epacomptox.24066012
Conley, J. Cumulative assessment approaches: Laboratory research informing multiple chemical exposures. Duke University ITEHP Spring 2023 Symposium, Durham, NC, February 17, 2023.
Conley, J., C. Lambright, N. Evans, A. Dixon, J. Ford, D. Jenkins-Hill, E. Hines, J. McCord, E. Medlock Kakaley, AND L. Gray. Dose addition-based approaches accurately predict maternal and neonatal effects in Sprague-Dawley rats from three different PFAS mixtures studies. Society of Toxicology 2023 Annual Meeting, Nashville, TN, March 19 - 23, 2023.
Conley, J., C. Lambright, N. Evans, A. Farraj, J. Smoot, R. Grindstaff, D. Jenkins-Hill, J. McCord, E. Medlock Kakaley, A. Dixon, E. Hines, AND L. Gray. Dose additive maternal and offspring effects of oral maternal exposure to a mixture of three PFAS (HFPO-DA, NBP2, PFOS) during pregnancy in the Sprague-Dawley rat. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 892:164609, (2023). https://doi.org/10.1016/j.scitotenv.2023.164609
MedlockKakaley, E., N. Evans, J. Conley, E. Gray, P. Bradley, K. Smalling, AND K. Romanok. Effects-based bioassay screening approaches applied to residential tapwater to inform consumer point-of-use decisions. Society of Environmental Toxicology and Chemistry, Louisville, KY, November 12 - 16, 2023.
Medlock Kakaley, E., N. Evans, M. Cardon, E. Green, J. Conley, L. Gray, P. Bradley, K. Smalling, AND K. Romanok. Effects-based tools to support consumers in tapwater use decisions: A multi-case study summary. National Water Quality Monitoring Council Meeting, Virginia Beach, VA, April 24 - 28, 2023.
Conley, J. Mixing PFAS – Mechanistic observations and dose additive effects in developmental toxicity studies of PFAS. University of Rochester Medical Center Environmental Health Sciences Center Seminar Series, Rochester, NY, May 11, 2023.
Conley, J. Practical Reproductive and Developmental Toxicology, Male Reproductive Biology and Toxicology. American College of Toxicology/Society for Birth Defects Research and Prevention Practical Reproductive and Developmental Toxicology, Gaithersburg, MD, May 22 - 26, 2023.
2022
Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, A. Dixon, D. Jenkins-Hill, J. McCord, M. Strynar, J. Ford, AND L. Gray. Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 170:107631, (2022). https://doi.org/10.1016/j.envint.2022.107631
Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, D. Jenkins-Hill, J. McCord, M. Strynar, L. Wehmas, S. Hester, D. Macmillan, AND L. Gray. Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS). ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 160:107056, (2022). https://doi.org/10.1016/j.envint.2021.107056
Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, M. Strynar, AND E. Gray. Developmental toxicity of emerging perfluoroalkyl ether carboxylic acids of varying chain length: PFMOAA, PFO4DA and PFO5DoA. Society for Birth Defects Research and Prevention, Raleigh, NC, June 25 - 29, 2022.
Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, J. Ford, J. McCord, M. Strynar, AND E. Gray. Evaluation of dose additive effects of combined oral maternal exposure to PFOA and PFOS during pregnancy in the Sprague-Dawley rat. 2022 Society of Toxicology Annual Meeting, San Diego, CA, March 27 - 31, 2022.
Gray, E., J. Conley, C. Lambright, AND J. FURR. In utero exposure to a mixture of the perfluoroalkyl-isopropyl pesticide pyrifluquinazon with dibutyl phthalate cumulatively disrupts male rat reproductive development via different mechanisms of action. Birth Defects Research and Prevention BDRP 2022, VANCOUVER, BRITISH COLOMBIA, CANADA, June 25 - 29, 2022.
Gray, E., J. Conley, C. Lambright, AND J. Furr. In utero exposure to a mixture of the perfluoroalkylisopropyl pesticide pyrifluquinazon with dibutyl phthalatecumulatively disrupts male rat reproductive development via different mechanisms of action. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(2):234-247, (2022). https://doi.org/10.1093/toxsci/kfac059
Evans, N., J. Conley, M. Cardon, P. Hartig, E. Medlock Kakaley, AND L. Gray. In vitro activity of a panel of per- and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals in peroxisome proliferator-activated receptor (PPAR) alpha, PPAR gamma, and estrogen receptor. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 449:116136, (2022). https://doi.org/10.1016/j.taap.2022.116136
Conley, J. PFAS developmental toxicity: evaluation of emerging compounds and mixtures in the Sprague-Dawley rat. Wayne State University School of Medicine Department of Pharmacology Seminar Series, Virtual, MI, January 28, 2022.
2021
Conley, J., C. Lambright, N. Evans, M. Cardon, E. MedlockKakaley, V. Wilson, AND E. Gray. A mixture of 15 phthalates and pesticides below individual chemical No Observed Adverse Effect Levels (NOAELs) produces reproductive tract malformations in the male rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 156(106615):1, (2021). https://doi.org/10.1016/J.ENVINT.2021.106615
MedlockKakaley, E., M. Cardon, N. Evans, C. Lambright, B. Blackwell, R. Hofer, L. Hubbard, P. Bradley, J. Conley, E. Gray, AND D. Kolpin. Biological Activity in US Food Processing Plant Effluent. SETAC Europe Annual Meeting (Virtual), Durham-Virtual, NC, May 03 - 06, 2021.
Gray, E., C. Lambright, N. Evans, V. Wilson, B. Hannas, P. Foster, AND J. Conley. Biological Relevance of Phthalate-Induced Disruption of Fetal Testis Hormones and Gene Expression: Key Events in a Novel AOP. Society of Toxicology - Virtual, NA, Virtual, March 12 - 26, 2021.
Conley, J. Characterization of developmental toxicity and Adverse Outcome Pathways (AOPs) for emerging PFAS – individual compounds and mixtures. Interagency Risk Assessment Consortium Information Sharing on PFAS, Virtual, Virtual, April 14 - 26, 2021.
Gray, E. AND J. Conley. Characterization of developmental toxicity and Adverse Outcome Pathways for emerging PFAS - individual compounds and mixtures. SOT Risk Assessment and Mixtures Specialty Sections Joint Webinar Series-Virtual, NA, Virtual, January 13, 2021.
Conley, J. Developmental toxicity of emerging PFAS in NC in the Sprague-Dawley rat. North Carolina Secretaries' Science Advisory Board-Virtual, Virtual, Virtual, April 05, 2021.