Science Inventory

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Watford, S. AND A. Shapiro. HAWC Presentation Summarizing previous quarter updates. HAWC Demo Updates to CalEPA, Washington, DC, October 20, 2023.

Friedman, K., M. Foster, L. Pham, M. Feshuk, S. Watford, J. Wambaugh, R. Judson, R. Setzer, AND R. Thomas. Reproducibility of organ-level effects in repeat dose animal studies. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 28:100287, (2023). https://doi.org/10.1016/j.comtox.2023.100287

Feshuk, M., S. Watford, L. Kolaczkowski, AND K. Friedman. ToxRefDB v2.1, a minor update to the Toxicity Reference Database. Society of Toxicology, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22270711

Feshuk, M., S. Watford, L. Kolaczkowski, AND K. Paul-Friedman. ToxRefDB v2.1, a minor update to the Toxicity Reference Database (NC Symp). NC Symposium on Life/Data Sciences, Precision Medicine/Environmental Health, RTP, NC, May 08, 2023. https://doi.org/10.23645/epacomptox.22270711

Feshuk, M., L. Kolaczkowski, S. Watford, AND K. Paul-Friedman. ToxRefDB v2.1: update to curated in vivo study data in the Toxicity Reference Database. Frontiers in Toxicology. Frontiers, Lausanne, Switzerland, 5:1260305, (2023). https://doi.org/10.3389/ftox.2023.1260305

Hoffman, S., E. Aissa, M. Angrish, C. Beausoleil, F. Bois, L. Ciccolallo, P. Craig, R. de Vries, J. Dorne, I. Druwe, S. Edwards, C. Eskes, M. Georgiadis, T. Hartung, A. Kienzler, E. Kristjansson, J. Lam, L. Martino, B. Meek, R. Morgan, I. Munoz-Guajardo, Pamela Noyes, E. Parmelli, A. Piersma, A. Rooney, E. Sena, K. Sullivan, J. Tarazona, A. Terron, K. Thayer, J. Turner, J. Verbeek, D. Verloo, M. Vinken, S. Watford, P. Whaley, D. Wikoff, K. Willett, AND K. Tsaioun. Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, , 1-20, (2022). https://doi.org/10.14573/altex.2202141

Feshuk, M., S. Watford, S. Addanki, W. Fies, J. Wignall, Amar V. Singh, AND K. Paul-Friedman. Capturing prenatal developmental toxicity data using the Data Collection Tool (DCT): Pilot curation summary. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19364711

Watford, S. Health Assessment Workspace Collaborative Demonstration. Workshops to Support EPA's Development of Human Health Assessments: Artificial Intelligence and Open Data Practices in Chemical Hazard Assessment, NA, DC, May 25 - 26, 2022.

Feshuk, M., L. Kolaczkowski, S. Addanki, K. Friedman, AND S. Watford. ToxRefDB version 2.1. U.S. Environmental Protection Agency, Washington, DC, 2022. https://doi.org/10.23645/epacomptox.6062545

Watford, S. Data Annotation, Extraction, and Interoperability for Chemical Assessments and Research. Automated Data Extraction, Washington DC, District Of Columbia, August 23, 2021.

Watford, S. Interoperability of Health Effects Data: Toxicity Reference Database (ToxRefDB). Scientific Liaison Coalition (SLC), NA, District Of Columbia, September 02, 2021.

Whaley, P., S. Edwards, A. Kraft, K. Nyhan, A. Shapiro, S. Watford, S. Wattman, T. Wolffe, AND M. Angrish. Knowledge Organization Systems for Systematic Chemical Assessments. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, , 1-11, (2020). https://doi.org/10.1289/EHP6994

Pham, L., S. Watford, P. Pradeep, M. Martin, R. Thomas, R. Judson, Woodrow Setzer, AND K. Paul-Friedman. Variability in in vivo studies: Defining the upper limit of performance for predictions of systemic effect levels. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 15(August 2020):100126, (2020). https://doi.org/10.1016/j.comtox.2020.100126

Brown, JasonM, S. Watford, AND K. Paul-Friedman. Bioinformatic Integration of in vivo Data and Literature-based Gene Associations for Prioritization of Adverse Outcome Pathway Development. Presented at Society of Toxicology annual meeting, Baltimore, MD, March 10 - 14, 2019. https://doi.org/10.23645/epacomptox.7844555

Watford, S. Bridging the Gap Between Data Sciences and Toxicologic Pathology: Chemical Screening and Prioritization. Presented at Society of Toxicologic Pathology annual symposium, Raleigh, NC, June 22 - 27, 2019.

Watford, S., S. Edwards, M. Angrish, R. Judson, AND K. Friedman. Progress in data interoperability to support computational toxicology and chemical safety evaluation. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 380(1 October 2019):114707, (2019). https://doi.org/10.1016/j.taap.2019.114707

Angrish, M., G. Woodall, S. Watford, AND P. Whaley. Role of Semantics, Ontologies, and Adverse Outcome Pathways as a Point of Integration in Chemical Assessments-Poster. NAS Evidence Integration, Washington, DC, June 03 - 04, 2019.

Watford, S., L. Pham, J. Wignall, R. Shin, M. Martin, AND K. Friedman. ToxRefDB version 2.0: Improved utility for predictive and retrospective toxicology analyses. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 89:145-158, (2019). https://doi.org/10.1016/j.reprotox.2019.07.012

Angrish, M., S. Watford, G. Hodge, G. Woodall, AND A. Mudambi. Enhancing Evidence Interpretation and Database Integration Via Semantic Matching. NAS Workshop on Systematic Review of Mechanistic Data, Washington, D.C, December 10 - 11, 2018.

Watford, S., L. Pham, J. Wignall, R. Shin, M. Martin, AND K. Paul-Friedman. New features in ToxRefDB to improve modeling applications and data integration. Presented at Society of Toxicology, San Antonio, Texas, March 11 - 15, 2018. https://doi.org/10.23645/epacomptox.6834827

Watford, S., R. Grashow, V. De La Rosa, R. Rudel, K. Paul-Friedman, AND M. Martin. Novel application of normalized pointwise mutual information (NPMI) to mine biomedical literature for gene sets associated with disease: Use case in breast carcinogenesis. Computational Toxicology. Elsevier B.V., Amsterdam, Netherlands, 7:46-57, (2018). https://doi.org/10.1016/j.comtox.2018.06.003

Pham, L., S. Watford, Woodrow Setzer, AND K. Paul-Friedman. Reproducibility and variance of liver effects in subchronic and chronic repeat dose toxicity studies. Society of Toxicology Annual Meeting, San Antonio,TX, March 11 - 15, 2018.

Watford, S. ToxRefDB 2.0: Improvements in Capturing Qualitative and Quantitative Data from in vivo Toxicity Studies and Implications for data integration. Bayer Crop Sciences Global Regulatory and Experimental Toxicology Meeting, RTP,NC, March 20, 2018.

Williams, A., Chris Grulke, S. Watford, R. Jolley, J. Dunne, E. Edmiston, AND J. Edwards. Bringing it all together: A Web-based Database for Chemical and Biological Data to Support Environmental Toxicology (ACS Fall meeting 8 of 12). Presented at ACS Fall Meeting, Washington, DC, August 20 - 24, 2017.

Karmaus, A., P. Kothiya, S. Watford, R. Thomas, AND M. Martin. Customizing the Connectivity Map Approach for Functional Evaluation in Toxicogenomics Studies (SOT). Presented at SOT National Meeting, Baltimore, MD, March 13 - 16, 2017. https://doi.org/10.23645/epacomptox.5176657