Science Inventory

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Breen, M., Z. Stanfield, K. Isaacs, V. Hull, J. Arnot, A. Sangion, M. Linakis, S. Davidson, C. Ring, M. Sfeir, AND J. Wambaugh. Human Exposure Prioritization using High-Throughput Toxicokinetics and Inferences for Volatile, Semi-volatile, and Non-volatile Environmental Chemicals. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22211875

Wambaugh, J., S. Davidson-Fritz, A. Meade, M. Breen, R. Sayre, T. Wall, E. Kenyon, M. Evans, B. Wetmore, AND C. Ring. Modelling kinetics and dynamics of chemicals at the U.S. Environmental Protection Agency using the httk open-source platform. Eurotox 2023, Ljubljana, SLOVENIA, September 10 - 13, 2023. https://doi.org/10.23645/epacomptox.24101718

Narain, M., M. Breen, J. Moyer, AND C. Ward-Caviness. Modification of the Association Between PM2.5 and Heart Rate by Beta-Blocker Usage Among Heart Failure Patients: SOT 2023. Society of Toxicology, Nashville, TN, March 19 - 23, 2023.

Breen, M., Z. Stanfield, K. Isaacs, V. Hull, J. Arnot, A. Sangion, M. Linakis, S. Davidson, J. Wambaugh, AND M. Sfeir. High-Throughput Toxicokinetics Exposure Inference for Environmental Organic Chemicals. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19333439

Narain, M., M. Breen, J. Moyer, AND C. Ward-Caviness. Modification of the Association Between PM2.5 and Heart Rate by Beta-Blocker Usage Among Heart Failure Patients. NC Society of Toxicology Annual Meeting, Chapel Hill, NC, October 19, 2022.

Wambaugh, J., M. Breen, S. Davidson-Fritz, AND C. Ring. Simulating Human Variability in Toxicokinetics with R Package “httk”. Human In, Human Out: Using Primary and Population Data for PBPK Analyses, Virtual, NC, November 10, 2022. https://doi.org/10.23645/epacomptox.21526299

Breen, M., J. Wambaugh, A. Bernstein, M. Sfeir, AND C. Ring. Simulating toxicokinetic variability to identify susceptible and highly exposed populations. Journal of Exposure Science and Environmental Epidemiology . Nature Publishing Group, London, Uk, 32:855-863, (2022). https://doi.org/10.1038/s41370-022-00491-0

Breen, M., C. Seppanen, V. Isakov, M. Breen, S. Arunachalam, J. Samet, R. Devlin, W. Cascio, D. Diaz-Sanchez, AND H. Tong. Smartphone App (TracMyAir) to Model Individual Exposures to Ambient Air Pollutants. The International Society of Exposure Science (ISES) 2020 Annual Meeting, NA, NC, September 20 - 24, 2020.

Tornero-Velez, R., D. Dawson, A. East, M. Breen, S. Brady, Dan Vallero, E. Hubal, AND J. Wambaugh. Using Systematic Evidence Mapping to Track the Development of Toxicokinetic Models of PFAS From 2000-2021. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19333283

Wambaugh, J., B. Wetmore, K. Paul-Friedman, S. Davidson, M. Devito, C. Ring, M. Breen, D. Kapraun, M. Evans, AND R. Thomas. EPA’s HTTK Research: In vitro Data and Generic TK Models for IVIVE. European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) invited workshop meeting, Brussels, N/A, BELGIUM, November 09 - 10, 2021. https://doi.org/10.23645/epacomptox.19131650

Breen, M., C. Ring, A. Kreutz, M. Goldsmith, AND J. Wambaugh. High-Throughput PBTK models for In Vitro to In Vivo Extrapolation. Expert Opinion on Drug Metabolism & Toxicology. Taylor & Francis Group, London, Uk, 17(8):903-921, (2021). https://doi.org/10.1080/17425255.2021.1935867

Breen, M., C. Ring, Z. Stanfield, K. Isaacs, V. Hull, J. Arnot, A. Sangion, M. Linakis, Mark A. Sfeir, AND J. Wambaugh. High-Throughput Toxicokinetics Exposure Inference for Environmental Chemicals. Society of Toxicology 2021 Virtual Annual meeting, RTP, NC, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.14466381

Ring, C., M. Breen, AND J. Wambaugh. Incorporating Population Variability in Toxicokinetic Modeling for Risk-Based Prioritization. Society of Toxicology Virtual Annual Meeting 2021, Virtual, NC, March 12 - 26, 2021. https://doi.org/10.23645/epacomptox.14498040

Breen, M., V. Isakov, C. Seppanen, S. Arunachalam, M. Breen, S. Prince, T. Long, D. Heist, P. Deshmukh, Keith Wyat Appel, C. Hogrefe, B. Murphy, Chris Nolte, G. Pouliot, H. Pye, AND J. Rosati. Integrating Time-Activity and Air Quality Sensors and Models into Smartphone-based PM2.5 and Ozone Exposure Model (TracMyAir). Annual Community Modeling and Analysis System (CMAS) Conference, Virtual, NC, November 01 - 05, 2021.

Breen, M., J. Wambaugh, A. Bernstein, M. Sfeir, AND C. Ring. Update of Open Source Population Variability Simulator for Toxicokinetic Modeling. 2021 ISES Annual Meeting (Virtual), Durham, North Carolina, August 30 - September 02, 2021. https://doi.org/10.23645/epacomptox.15144273

Breen, M., J. Nwanaji-Enwerem, S. Karrasch, C. Flexeder, H. Schulz, M. Waldenberger, S. Kunze, M. Ollert, S. Weidinger, E. Colicino, X. Gao, C. Wang, J. Shen, A. Just, P. Vokonas, L. Hou, J. Schwartz, A. Baccarelli, A. Peters, C. Ward-Caviness, AND D. Sparrow. Accelerated Epigenetic Aging as a Risk Factor for Chronic Obstructive Pulmonary Disease and Decreased Lung Function in two Prospective Cohort Studies. Aging. Impact Journals, LLC, Orchard Park, NY, 12(16):16539-16554, (2020). https://doi.org/10.18632/aging.103784

Breen, M., S. Chang, M. Breen, Y. Xu, V. Isakov, S. Arunachalam, M. Carraway, AND R. Devlin. Fine-Scale Modeling of Individual Exposures to Ambient PM2.5, EC, NOx, CO for the Coronary Artery Disease and Environmental Exposure (CADEE) Study. ATMOSPHERE. MDPI, Basel, Switzerland, 11(1):65, (2020). https://doi.org/10.3390/atmos11010065

Wambaugh, J., M. Linakis, M. Evans, K. Isaacs, R. Sayre, Chris Grulke, R. Pearce, Mark A. Sfeir, M. Breen, N. Sipes, H. Pangburn, AND J. Gearhart. High Throughput Toxicokinetic (HTTK) Modeling of Inhalation Exposures. American Chemical Society Annual Meeting, Virtual, California, August 17 - 20, 2020. https://doi.org/10.23645/epacomptox.16663450

Breen, M., J. Arnot, A. Sangion, K. Isaacs, M. Linakis, M. Sfeir, AND J. Wambaugh. High-Throughput Toxicokinetics Inhalation Exposure Inferences for Organic Chemicals. ISES 2020 Virtal Meeting, Virtual, Virtual, September 21 - 22, 2020. https://doi.org/10.23645/epacomptox.13180118

Breen, M., C. Seppanen, V. Isakov, S. Arunachalam, M. Breen, J. Samet, H. Tong, AND W. Cascio. Integrating CMAQ Model into Smartphone App (TracMyAir) for Modeling Exposures to Ambient PM2.5 and Ozone. 19th Annual Community Modeling and Analysis System (CMAS) Conference, NA, NC, October 26 - 30, 2020.

Breen, M., Y. Xu, M. Breen, V. Isakov, AND R. Devlin. Modeling of Residential Indoor Concentrations of Ambient PM2.5, Ozone for the Catheterization Genetics (CATHGEN) Study. ISEE Annual Conference, NA, Virtual Meeting, August 23 - 27, 2020.

Breen, M., W. Cascio, J. Moyer, J. Schwartz, Q. Di, E. Pfaff, R. Devlin, D. Diaz-Sanchez, AND C. Ward-Caviness. Short-term Effects of Fine Particulate Matter on Heart Rate in Heart Failure Patients. International Society of Environmental Epidemiology 2020 Virtual Meeting (ISEE), Virtual, Virtual, August 23 - 27, 2020. https://doi.org/10.23645/epacomptox.13268816

Breen, M., C. Seppanen, Vladilen Isakov, S. Arunachalam, M. Breen, J. Samet, AND H. Tong. Development of TracMyAir Smartphone Application for Modeling Exposures to Ambient PM2.5 and Ozone. International Journal of Environmental Research and Public Health. Molecular Diversity Preservation International, Basel, Switzerland, 16(18):3468, (2019). https://doi.org/10.3390/ijerph16183468

Breen, M., Dan Villeneuve, G. Ankley, D. Bencic, K. Watanabe, A. Lloyd, AND R. Conolly. Computational Model of the Fathead Minnow Hypothalamic-Pituitary-Gonadal Axis: Incorporating Protein Synthesis in Improving Predictability of Responses to Endocrine Active Chemicals. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY PART C. Elsevier Science Ltd, New York, NY, 183:36-45, (2016).

Breen, M., J. Burke, S. Batterman, A. Vette, G. Norris, C. Godwin, M. Landis, C. Croghan, Brad Schultz, AND M. Breen. Air Pollution Exposure Model for Individuals (EMI) in Health Studies. Presented at 2014 Annual Meeting of the Society of Toxicology, Phoenix, AR, March 23 - 27, 2014.