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Records 1 to 25 of 31 records from author Ronald Hines

2023
Rowan, E., R. Hines, S. Vulimiri, B. Wetmore, C. Brinkerhoff, A. Jarabek, D. Kapraun, E. Kenyon, C. Ring, J. Wambaugh, AND R. Sayre. Constructing An Enzyme Ontogeny Database to Improve Characterization of Toxicokinetic Lifestage Differences (Poster). Society of Toxicology, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22266274
Rowan, E., R. Hines, Suryanarayana Vulimiri, B. Wetmore, C. Brinkerhoff, A. Jarabek, D. Kapraun, E. Kenyon, C. Ring, J. Wambaugh, AND R. Sayre. Constructing an Enzyme Ontogeny Database to Improve Characterization of Toxicokinetic Lifestage Differences. NC Symposium on Life/Data Sciences, Precision Medicine/Environmental Health, RTP, NC, May 08, 2023. https://doi.org/10.23645/epacomptox.22266274
2020
Comess, S., A. Akbay, M. Vasiliou, R. Hines, L. Joppa, V. Vasiliou, AND N. Kleinstreuer. Bringing Big Data to Bear in Environmental Public Health: Challenges and Recommendations. Frontiers in Artificial Intelligence. Frontiers, Lausanne, Switzerland, 3:31, (2020). https://doi.org/10.3389/frai.2020.00031
Mallick, P., M. Moreau, G. Song, A. Efremenko, S. Pendse, M. Creek, T. Osimitz, R. Hines, P. Hinderliter, H. Clewell, B. Lake, AND M. Yoon. Development and Application of a Life-Stage Physiologically-Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 173(1):86-99, (2020). https://doi.org/10.1093/toxsci/kfz211
2019
Patlewicz, G., A. Richard, A. Williams, C. Grulke, R. Sams, J. Lambert, Pamela Noyes, M. DeVito, R. Hines, M. Strynar, A. GuiseppiElie, AND R. Thomas. A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 127(1):1-12, (2019). https://doi.org/10.1289/EHP4555
Matlock, M., A. Tambe, J. Elliott-Higgins, R. Hines, G. Miller, AND S. Swamidass. A time-embedding network models the ontogeny of 23 hepatic drug metabolizing enzymes. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 32(8):1707-1721, (2019). https://doi.org/10.1021/acs.chemrestox.9b00223
Dubaisi, S., J. Caruso, R. Gaedigk, C. Vyhlidal, P. Smith, R. Hines, T. Kocarek, AND M. Runge-Morris. Developmental Expression of the Cytosolic Sulfotransferases in Human Liver. DRUG METABOLISM AND DISPOSITION. American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD, 47(6):592-600, (2019). https://doi.org/10.1124/dmd.119.086363
Hines, R. Risk-Based PFAS Toxicological Testing Strategy to Inform Decision-Making. Invited Presentation, Kingston, Rhode Island, April 24, 2019.
Kenyon, E., J. Lipscomb, R. Pegram, BJ George, AND R. Hines. THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT PHARMACOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM). TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(2):347-359, (2019). https://doi.org/10.1093/toxsci/kfy236
Hines, R. Toxicological and Pharmacological Challenges While Growing-Up. RTP Drug Metabolism Interest Group, Durham, North Carolina, December 03, 2019.
2018
Kenyon, E., R. Pegram, J. Lipscomb, AND R. Hines. Impact of Scaling Factor Variation on Pharmacokinetic Outcomes in Pediatric Populations: a Case Study Using Bromodichloromethane (BDCM). FutureTox IV, Crystal City, VA, November 14 - 16, 2018.
2017
Song, G., X. Sun, R. Hines, D. McCarver, B. Lake, T. Osimitz, M. Creek, H. Clewell, AND M. Yoon. Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages. DRUG METABOLISM AND DISPOSITION. American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD, 45(5):468-475, (2017).
Gwinn, M., D. Berry, A. Kirk, T. Bateson, B. Benson, S. Gavett, A. Jarabek, L. Kopylev, D. Bussard, R. Hines, D. McKean, AND M. Scozzafava. Finalizing the Libby Action Plan Research Program. Johnson Conference, Burlington, Vermont, July 31 - August 04, 2017.
Juberg, D., T. Knudsen, M. Sander, N. Beck, E. Faustman, D. Mendrick, J. Fowle, T. Hartung, R. Tice, E. Lamazurier, R. Becker, S. Fitzpatrick, G. Daston, A. Harill, R. Hines, D. Keller, J. Lipscomb, D. Watson, T. Bahadori, AND K. Crofton. FutureTox III: Bridges for Translation. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 155(1):22-31, (2017).
Hines, R. Open Data in Biomedical Science: Policy Drivers and Recent Progress. 56th Annual Society of Toxicology Meeting, Baltimore, MD, March 12 - 16, 2017.
Hines, R. Reflections on a Personal Journey; Learning to Become a Scientific Leader. 56th Annual Society of Toxicology Meeting, Baltimore, MD, March 12 - 16, 2017.
Hines, R. Risk Assessment in the 21st Century - Conference Abstract. Yale Environmental Health Sciences Lecture Series, New Haven, CT, January 25, 2017.
Kenyon, E., R. Pegram, AND R. Hines. Scaling Factor Variability and Toxicokinetic Outcomes in Children. Childrens Environmental Health Network Research Conference, Washington, DC, April 05 - 07, 2017.
Kenyon, E., J. Lipscomb, R. Pegram, AND R. Hines. THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT TOXICOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM). Society of Toxicology, Baltimore, Maryland, March 12 - 16, 2017.
2016
Hines, R., P. Simpson, AND D. McCarver. Age-Dependent Human Hepatic Carboxylesterase 1 (Ces1) and Carboxylesterase 2 (Ces2) Postnatal Ontogeny. DRUG METABOLISM AND DISPOSITION: BIOLOGICAL FATE OF CHEMICALS. American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD, 44(7):959-966, (2016).
Hines, R. AND B. Chorley. Application of miRNAs as Biomarkers of Exposure and Effects in Risk Evaluation. Environmental Mutagen and Genomics Society Annual Meeting, Kansas City, MO, September 24 - 28, 2016.
El-Masri, H., N. Kleinstreuer, R. Hines, Lindad Adams, T. Tal, K. Isaacs, B. Wetmore, AND C. Tan. Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 152(1):230-243, (2016).
Hines, R. Risk Assessment in the 21st Century. John Doull Toxicology Symposium, Kansas City, Kansas, September 14 - 15, 2016.
2015
Song, G., X. Sun, R. Hines, D. McCarver, B. Lake, T. Osimitz, M. Creek, H. Clewell, AND M. Yoon. Age-Dependent Changes in Human Hepatic CYP2C8 and 1A2 Expression. Society of Toxicology Annual Meeting, San Diego, CA, March 22 - 26, 2015.
Carlin, D., T. Larson, J. Pfau, S. Gavett, A. Shukla, A. Miller, AND R. Hines. Current Research and Opportunities to Address Environmental Asbestos Exposures. In Proceedings, Society of Toxicology, Phoenix, AZ, March 23 - 27, 2014. Environmental Health Perspectives, Research Triangle Park, NC, A194-7, (2015).