Science Inventory

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Jackson, T., C. Lambright, N. Evans, L. Wehmas, D. Macmillan, J. Bangma, L. Gray, AND J. Conley. Exploring maternal and developmental toxicity of PFO4DA and PFO5DoA using hepatic transcriptomics and serum metabolomics. Society of Toxicology Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.

Conley, J., C. Lambright, N. Evans, J. Bangma, J. Ford, D. Jenkins-Hill, AND L. Gray. Maternal, fetal, and neonatal toxicity of the long-chain, multi-ether PFAS PFO5DoA in the Sprague-Dawley rat. Society of Toxicology 2024 Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024.

Brinkman, N., M. Jahne, J. Garland, S. Keely, E. Wheaton, M. Nagarkar, S. Homa, S. Thimons, E. Medlock Kakaley, N. Evans, K. Dirks, D. Snow, AND C. Williams. Risk-Based Treatment Needs for Water Reuse in Protein Processing Facilities. Presented at 2024 WateReuse Symposium, Denver, CO, March 11 - 14, 2024.

Bradley, P., K. Romanok, K. Smalling, M. Focazio, N. Evans, S. Fitzpatrick, C. Givens, S. Gordon, J. Gray, E. Green, D. Griffin, M. Hladik, L. Kanagy, J. Lisle, K. Loftin, R. McCleskey, E. Medlock Kakaley, A. Navas-Acien, D. Roth, AND C. Weis. Bottled Water Contaminant Exposures and Predicted Human Effects. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 171(107701):1, (2023). https://doi.org/10.1016/j.envint.2022.107701

Conley, J., C. Lambright, N. Evans, A. Dixon, J. Ford, D. Jenkins-Hill, E. Hines, J. McCord, E. Medlock Kakaley, AND L. Gray. Dose addition-based approaches accurately predict maternal and neonatal effects in Sprague-Dawley rats from three different PFAS mixtures studies. Society of Toxicology 2023 Annual Meeting, Nashville, TN, March 19 - 23, 2023.

Conley, J., C. Lambright, N. Evans, A. Farraj, J. Smoot, R. Grindstaff, D. Jenkins-Hill, J. McCord, E. Medlock Kakaley, A. Dixon, E. Hines, AND L. Gray. Dose additive maternal and offspring effects of oral maternal exposure to a mixture of three PFAS (HFPO-DA, NBP2, PFOS) during pregnancy in the Sprague-Dawley rat. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 892:164609, (2023). https://doi.org/10.1016/j.scitotenv.2023.164609

MedlockKakaley, E., N. Evans, J. Conley, E. Gray, P. Bradley, K. Smalling, AND K. Romanok. Effects-based bioassay screening approaches applied to residential tapwater to inform consumer point-of-use decisions. Society of Environmental Toxicology and Chemistry, Louisville, KY, November 12 - 16, 2023.

Medlock Kakaley, E., N. Evans, M. Cardon, E. Green, J. Conley, L. Gray, P. Bradley, K. Smalling, AND K. Romanok. Effects-based tools to support consumers in tapwater use decisions: A multi-case study summary. National Water Quality Monitoring Council Meeting, Virginia Beach, VA, April 24 - 28, 2023.

Bradley, P., D. Kolpin, D. Thompson, K. Romanok, K. Smalling, S. Breitmeyer, D. Cwiertny, N. Evans, R. Field, M. Focazio, L. Freeman, C. Givens, J. Gray, G. Hager, M. Hladik, J. Hofmann, R. Jones, L. Kanagy, R. Lane, R. McCleskey, D. Medgyesi, E. Medlock Kakaley, S. Meppelink, M. Meyer, D. Stavreva, M. Ward, AND M. Cardon. Juxtaposition of Intense Agriculture, Vulnerable Aquifers, and Mixed Chemical/Microbial Exposures in Private-Well Tapwater in Northeast Iowa. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 868:161672, (2023). https://doi.org/10.1016/j.scitotenv.2023.161672

Green, E., M. Cardon, N. Evans, AND E. MedlockKakaley. Application of the Generalized Concentration Addition Model to Predict In Vitro Responses of Tertiary Mixtures of Glucocorticoid Ligands@. Society of Toxicology, San Diego, California, March 27 - 31, 2022.

Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, A. Dixon, D. Jenkins-Hill, J. McCord, M. Strynar, J. Ford, AND L. Gray. Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 170:107631, (2022). https://doi.org/10.1016/j.envint.2022.107631

Conley, J., C. Lambright, N. Evans, E. Medlock Kakaley, D. Jenkins-Hill, J. McCord, M. Strynar, L. Wehmas, S. Hester, D. Macmillan, AND L. Gray. Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) and perfluorooctane sulfonate (PFOS). ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 160:107056, (2022). https://doi.org/10.1016/j.envint.2021.107056

Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, M. Strynar, AND E. Gray. Developmental toxicity of emerging perfluoroalkyl ether carboxylic acids of varying chain length: PFMOAA, PFO4DA and PFO5DoA. Society for Birth Defects Research and Prevention, Raleigh, NC, June 25 - 29, 2022.

Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, J. Ford, J. McCord, M. Strynar, AND E. Gray. Evaluation of dose additive effects of combined oral maternal exposure to PFOA and PFOS during pregnancy in the Sprague-Dawley rat. 2022 Society of Toxicology Annual Meeting, San Diego, CA, March 27 - 31, 2022.

Evans, N., J. Conley, M. Cardon, P. Hartig, E. Medlock Kakaley, AND L. Gray. In vitro activity of a panel of per- and polyfluoroalkyl substances (PFAS), fatty acids, and pharmaceuticals in peroxisome proliferator-activated receptor (PPAR) alpha, PPAR gamma, and estrogen receptor. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 449:116136, (2022). https://doi.org/10.1016/j.taap.2022.116136

Cavallin, J., C. Adams, L. Barber, B. Blackwell, P. Bradley, A. Cole, D. Ekman, N. Evans, S. Keefe, K. Keteles, J. Kinsey, E. MedlockKakaley, K. Romanok, K. Santana Rodriguez, K. Smalling, E. Stacy, D. Winkelman, AND Dan Villeneuve. Spatial and Temporal Distribution of Glucocorticoid and Estrogen Receptor-Mediated Bioactivities in Relation to a Wastewater Input on the South Platte River (Denver, CO, USA). Society of Environmental Toxicology and Chemistry (SETAC) North America, Pittsburgh, PA, November 13 - 17, 2022. https://doi.org/10.23645/epacomptox.21424551

Bradley, P., E. Medlock Kakaley, K. Romanok, K. Smalling, M. Focazio, R. Charboneau, C. George, A. Navas-Acien, M. O'Leary, R. Red Cloud, T. Zacher, S. Breitmeyer, M. Cardon, C. Cuny, G. Ducheneaux, K. Enright, N. Evans, J. Gray, D. Harvey, M. Hladik, K. Loftin, R. McClesky, S. Meppelink, J. Valder, C. Weiss, AND L. White. Tapwater Exposures, Effects Potential, and Residential Risk Management in Northern Plains Nations. ACS ES&T Water. American Chemical Society, Washington, DC, 2(10):1772-1788, (2022). https://doi.org/10.1021/acsestwater.2c00293

Conley, J., C. Lambright, N. Evans, M. Cardon, E. MedlockKakaley, V. Wilson, AND E. Gray. A mixture of 15 phthalates and pesticides below individual chemical No Observed Adverse Effect Levels (NOAELs) produces reproductive tract malformations in the male rat. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, Netherlands, 156(106615):1, (2021). https://doi.org/10.1016/J.ENVINT.2021.106615

Green, E., N. Evans, AND E. MedlockKakaley. Application of the Generalized Concentration Addition Model to Predict In Vitro Responses of Tertiary Mixtures of Glucocorticoid Ligands. Society of Toxicology - Virtual, N/A, Virtual, March 12 - 26, 2021.

Green, E., E. MedlockKakaley, M. Cardon, AND N. Evans. Application of the Generalized Concentration Addition Model to Predict In Vitro Responses of Tertiary Mixtures of Glucocorticoid Ligands-extended abstract for SOT award. Society of Toxicology, Durham, North Carolina, March 12 - 26, 2021.

MedlockKakaley, E., M. Cardon, N. Evans, C. Lambright, B. Blackwell, R. Hofer, L. Hubbard, P. Bradley, J. Conley, E. Gray, AND D. Kolpin. Biological Activity in US Food Processing Plant Effluent. SETAC Europe Annual Meeting (Virtual), Durham-Virtual, NC, May 03 - 06, 2021.

Gray, E., C. Lambright, N. Evans, V. Wilson, B. Hannas, P. Foster, AND J. Conley. Biological Relevance of Phthalate-Induced Disruption of Fetal Testis Hormones and Gene Expression: Key Events in a Novel AOP. Society of Toxicology - Virtual, NA, Virtual, March 12 - 26, 2021.

Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, D. Hill, A. Dixon, E. Hines, AND E. Gray. Dose additive developmental toxicity of a mixture of three PFAS (HFPO-DA, NBP2, PFOS) in the Sprague-Dawley rat. 2021 Society of Toxicology Annual Meeting-Virtual, NA, Virtual, March 12 - 26, 2021.

MacMillan, D., N. Evans, E. Gray, C. Lambright, AND J. Conley. Exploring Potential Differences in Developmental Toxicology of Per- and Polyfluoroalkyl Substances (PFAS) Through Targeted Metabolomics. American Society for Mass Spectrometry Conference, Philadelphia, Pennsylvania, October 30 - November 04, 2021. https://doi.org/10.23645/epacomptox.16840390

Conley, J., C. Lambright, N. Evans, E. MedlockKakaley, AND E. Gray. Exposure to a mixture of PFOA and PFOS during pregnancy produces cumulative effects on F1 bodyweight, liver weight, and survival in the Sprague-Dawley rat. FLUOROS Global 2021, Providence, RI, October 03 - 07, 2021.