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25
of 118 records from author Marina Evans
2024
Schacht, C., M. Evans, AND J. Wambaugh. Development of a high throughput PBTK model for co-exposure as part the software package (httk). SOT, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25395520
Evans, M. New Approach Methods (NAMs) for PBPK and Internal Dose. UNC ENVR500, Chapel Hill, NC, April 02, 2024. https://doi.org/10.23645/epacomptox.26015209
2023
Fisher, H., M. Evans, A. Bunge, E. Cohen-Hubal, AND D. Vallero. A compartment model to predict in vitro finite dose absorption of chemicals by human skin. CHEMOSPHERE. Elsevier Science Ltd, New York, NY, 349:140689, (2024). https://doi.org/10.1016/j.chemosphere.2023.140689
Evans, M., T. Moxon, G. Lian, B. Deacon, T. Chen, L. Adams, A. Meade, AND J. Wambaugh. A regression analysis using simple descriptors for multiple dermal datasets: Going from individual membranes to the full skin. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 43(6):940-950, (2023). https://doi.org/10.1002/jat.4435
Evans, M. Application of High Throughput Toxicokinetics (httk): Dermal Route Development. NCSU, Raleigh, NC, April 13, 2023. https://doi.org/10.23645/epacomptox.22587838
Evans, M. Application of High Throughput Toxicokinetics (httk): Dermal Route Development (UNC 2023). UNC, Chapel Hill, NC, November 04, 2023. https://doi.org/10.23645/epacomptox.24554191
Evans, M. Application of PBPK modeling: Environmental exposure to internal dose and toxicity. NCSU, Raleigh, NC, February 23, 2023. https://doi.org/10.23645/epacomptox.22105064
Evans, M., A. Meade, G. Lian, B. Deacon, T. Chen, AND J. Wambaugh. Application of a high throughput physiology based pharmacokinetic/toxicokinetic (httk) dermal route using human in vivo caffeine exposure data. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22207225
Fisher, H., M. Evans, E. Hubal, AND Dan Vallero. Applying a mass-balance model to predict human in vitro dermal absorption of data poor chemicals. ISES, Chicago, IL, August 27 - 31, 2023. https://doi.org/10.23645/epacomptox.23902194
Stevens, J., A. Prockter, H. Fisher, H. Tran, AND M. Evans. Chemical absorption in the layers of human skin (NCSU 2023). NCSU, Raleigh, NC, November 18 - 19, 2023. https://doi.org/10.23645/epacomptox.24970104
Deacon, B., S. Silva, G. Lian, M. Evans, AND T. Chen. Development and Initial Results from the Inclusion of Evaporation into a 2D dermal absorption model. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22207186
Meade, A., M. Evans, AND J. Wambaugh. Development and analysis of high throughput physiologically based pharmacokinetic/toxicokinetic (PBPK/TK) dermal exposure model. SOT, Nashville, TN, March 19 - 23, 2023. https://doi.org/10.23645/epacomptox.22637536
Evans, M. AND C. Schacht. High Throughput Toxicokinetics (httk) Modeling Virtual Training. NAMs Training, Virtual, NC, November 08 - 09, 2023. https://doi.org/10.23645/epacomptox.24383647
Wambaugh, J., S. Davidson-Fritz, A. Meade, M. Breen, R. Sayre, T. Wall, E. Kenyon, M. Evans, B. Wetmore, AND C. Ring. Modelling kinetics and dynamics of chemicals at the U.S. Environmental Protection Agency using the httk open-source platform. Eurotox 2023, Ljubljana, SLOVENIA, September 10 - 13, 2023. https://doi.org/10.23645/epacomptox.24101718
2022
Stevens, J., A. Prockter, H. Fisher, H. Tran, AND M. Evans. Chemical absorption in the layers of human skin. Women in Scientific Computing, Gainesville, FL, October 25, 2022. https://doi.org/10.23645/epacomptox.21395229
Fisher, H., M. Evans, C. Eklund, Dan Vallero, A. Bunge, AND E. Hubal. Dermal Absorption Model. ISES, Lisbon, PORTUGAL, September 25 - 29, 2022. https://doi.org/10.23645/epacomptox.21190201
Fisher, H., M. Evans, A. Bunge, Dan Vallero, C. Eklund, AND E. Hubal. Dermal absorption modeling for in-vitro experiments using human skin for fragrance chemicals - approach and challenges. Society of Toxicology, San Diego, CA, March 27 - 31, 2022. https://doi.org/10.23645/epacomptox.19401218
2021
Wambaugh, J., B. Wetmore, K. Paul-Friedman, S. Davidson, M. Devito, C. Ring, M. Breen, D. Kapraun, M. Evans, AND R. Thomas. EPA’s HTTK Research: In vitro Data and Generic TK Models for IVIVE. European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) invited workshop meeting, Brussels, N/A, BELGIUM, November 09 - 10, 2021. https://doi.org/10.23645/epacomptox.19131650
Evans, M. Sensitivity Analysis- Theory and PBPK Applications. OECD, Paris (Virtual Meeting), Virtual, NC, April 30 - May 10, 2021. https://doi.org/10.23645/epacomptox.17430104
2020
Evans, M., C. Eklund, D. williams, Y. Sey, AND J. Simmons. Global Optimization of the Michaelis-Menten parameters using physiologically-based pharmacokinetic (PBPK) modeling and chloroform vapor uptake data in F344 rats. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, 32(3):97-109, (2020). https://doi.org/10.1080/08958378.2020.1742818
Wambaugh, J., M. Linakis, M. Evans, K. Isaacs, R. Sayre, Chris Grulke, R. Pearce, Mark A. Sfeir, M. Breen, N. Sipes, H. Pangburn, AND J. Gearhart. High Throughput Toxicokinetic (HTTK) Modeling of Inhalation Exposures. American Chemical Society Annual Meeting, Virtual, California, August 17 - 20, 2020. https://doi.org/10.23645/epacomptox.16663450
Fisher, H., E. Hubal, M. Evans, A. Bunge, A. Jarabek, AND Dan Vallero. Proposed Suite of Models for Estimating Dose Resulting from Exposures by the Dermal Route (SETAC). The Society of Environmental Toxicology and Chemistry (SETAC) North America 41st Annual Meeting, RTP, NC, November 15 - 19, 2020. https://doi.org/10.23645/epacomptox.13503201
2019
Evans, M. Optimization of metabolic parameters using physiologically based pharmacokinetic (PBPK) modeling and chloroform (CHCl3) vapor-uptake inhalation data in F344 rats. Society ot Toxicology Annual Meeting, Baltimore, Maryland, March 10 - 14, 2019.
2018
Eklund, C., M. Evans, H. Yang, Y. Sey, AND J. Simmons. A Physiologically-Based Pharmacokinetic (PBPK) Model With Metabolic Interactions of Chloroform (CHCL3) and Trichloroethylene. Society of Toxicology, San Antonio, TX, March 11 - 15, 2018.
Evans, M. Computational prediction of dermal diffusivity for large number of chemicals – challenges and applications. Society of Toxicology, San Antonio, Texas, March 11 - 15, 2018.