Science Inventory

Carlson, L., K. Christensen, S. Sagiv, P. Rajan, C. Klocke, P. Lein, E. Coffman, R. Shaffer, E. Yost, X. Arzuaga Andino, P. Factor-Litvak, A. Sergeev, M. Toborek, M. Bloom, J. Trgovcich, T. Jusko, L. Robertson, J. Meeker, A. Keating, R. Blain, R. Silva, S. Snow, C. Lin, K. Shipkowski, B. Ingle, AND G. Lehmann. A Systematic Evidence Map for The Evaluation of Noncancer Health Effects and Exposures to Polychlorinated Biphenyl Mixtures. ENVIRONMENTAL RESEARCH. Elsevier B.V., Amsterdam, Netherlands, 220:115148, (2023). https://doi.org/10.1016/j.envres.2022.115148

Lowe, K., Jeffrey Dawson, K. Phillips, J. Minucci, J. Wambaugh, H. Qian, T. Ramanarayanan, P. Egeghy, B. Ingle, R. Brunner, E. Mendez, M. Embry, AND C. Tan. Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 127:105073, (2021). https://doi.org/10.1016/j.yrtph.2021.105073

Tan, C., H. Barton, A. Boobis, R. Brunner, H. Clewell, R. Cope, Jeffrey Dawson, J. Domoradzki, P. Egeghy, P. Gulati, B. Ingle, N. Kleinstreuer, K. Lowe, A. Lowit, E. Mendez, David J Miller, J. Minucci, J. Nguyen, A. Paini, M. Perron, K. Phillips, H. Qian, T. Ramanarayanan, F. Sewell, P. Villanueva, J. Wambaugh, AND M. Embry. Opportunities and challenges related to saturation of toxicokinetic processes: implications for risk evaluation. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 127:105070, (2021). https://doi.org/10.1016/j.yrtph.2021.105070

Shipkowski, K., J. Trgovcich, N. Vetter, B. Ingle, R. Silva, L. Carlson, D. Kapraun, P. Schlosser, AND G. Lehmann. Advancing Kinetic Modeling for Polychlorinated Biphenyl (PCB) Mixtures Relevant to Human Exposures: A Case Study Applying the KeywordAnalysis Tool to PCBs Congener-Specific Half-Lives. International Society for Environmental Epidemiology, Washington DC, NC, August 23 - 27, 2020.

Ingle, B., K. McKinley, G. Glen, C. Henning, M. Follansbee, G. Diamond, AND James Brown. All-Ages Lead Model (Aalm) Batch Submission Module: A New Tool for Streamlined Human Lead Toxicokinetic Simulations (Presentation, 2020). Society of Toxicology 2020 Annual Meeting, Anaheim, California, March 15 - 19, 2020.

Ingle, B., B. Veber, J. Nichols, J. Wambaugh, AND R. Tornero-Velez. Designing a Quantitative Structure-Activity Relationship for the Intrinsic Metabolic Clearance of Environmentally Relevant Chemicals. Presented at Society of Toxicology 56th Annual Meeting and ToxExpo, Baltimore, MD, March 12 - 16, 2017.

Ingle, B., B. Veber, J. Nichols, J. Wambaugh, AND R. Tornero-Velez. In Silico Prediction of Toxicokinetic Parameters for Environmentally Relevant Chemicals for Risk-Based Prioritization. OpenTox USA 2017, Durham, NC, July 12 - 13, 2017.

Ingle, B., B. Veber, J. Nichols, J. Wambaugh, AND R. Tornero-Velez. In Silico Prediction of Toxicokinetic Parameters for Environmentally Relevant Chemicals with Application to Risk-Based Prioritization. 2017 ISES Annual Meeting, Research Triangle Park, NC, October 15 - 19, 2017.

Wambaugh, J., B. Wetmore, K. Mansouri, B. Ingle, R. Tornero-Velez, R. Judson, K. Isaacs, K. Phillips, C. Nicolas, Woodrow Setzer, AND R. Thomas. Integrating Toxicity, Toxicokinetic, and Exposure Data for Risk-based Chemical Alternatives Assessment. International Society of Exposure Science annual meeting, Morrisville,NC, October 15 - 19, 2017.

Pearce, R., B. Ingle, R. Tornero-Velez, B. Wetmore, Woodrow Setzer, AND J. Wambaugh. Rapid Prototyping of Physiologically-Based Toxicokinetic (PBTK) Models (SOT annual meeting). Presented at Society of Toxicology Annual Meeting, Baltimore, Maryland, March 12 - 16, 2017. https://doi.org/10.23645/epacomptox.5178598

Wetmore, B., J. Wambaugh, K. Isaacs, R. Tornero-Velez, R. Thomas, J. Simmons, Woodrow Setzer, R. Sayre, R. Pearce, D. Kapraun, B. Ingle, M. Hughes, Chris Grulke, M. Ecklund, M. Evans, AND Lindad Adams. Evaluating and Refining High Throughput Tools for Toxicokinetics. CSS BoSC Meeting, RTP, NC, November 16 - 18, 2016.

Nicolas, C., B. Ingle, M. Bacolod, J. Gilbert, B. Wetmore, C. Ring, Woodrow Setzer, R. Tornero-Velez, M. Martin, AND J. Wambaugh. High Throughput Determination of Critical Human Dosing Parameters (SOT). Presented at SOT 55th Annual Meeting and ToxExpo, New Orleans, LA, March 13 - 17, 2016.

Nicolas, C., B. Ingle, M. Bacolod, J. Gilbert, B. Wetmore, C. Ring, Woodrow Setzer, R. Tornero-Velez, M. Martin, AND J. Wambaugh. High Throughput Determinations of Critical Dosing Parameters (IVIVE workshop). Presented at IVIVE for HT Prioritization and Decision Making, Durham, NC, February 17 - 18, 2016. https://doi.org/10.23645/epacomptox.5189194

Ingle, B., B. Veber, J. Nichols, AND R. Tornero-Velez. Human health and the environment: Predicting plasma protein binding and metabolic clearance rates of environmentally relevant chemicals. American Chemical Society Nat'l Meeting, San Diego, CA, San Diego, CA, March 13 - 17, 2016.

Ingle, B., R. Tornero-Velez, J. Nichols, AND B. Veber. Informing the Human Plasma Protein Binding of Environmental Chemicals by Machine Learning in the Pharmaceutical Space: Applicability Domain and Limits of Predictability. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 56(11):2243-2252, (2016).

Ingle, B., B. Veber, J. Nichols, AND R. Tornero-Velez. Toxicity challenges in environmental chemicals: Prediction of human plasma protein binding through quantitative structure-activity relationship (QSAR) models. IVIE Workshop RTP, NC, RTP, NC, February 17, 2016.

Ingle, B., B. Veber, J. Nichols, AND R. Tornero-Velez. Toxicity challenges in environmental chemicals: Prediction of human plasma protein binding through quantitative structure-activity relationship (QSAR) models (2016 IVIVE Workshop Proceedings). In Proceedings, IVIVE Workshop, RTP, NC, February 17, 2016. U.S. Department of Health & Human Services, NIEHS, Research Triangle Park, NC, 4, (2016).