Science Inventory

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Judson, R., D. Smith, M. Devito, J. Wambaugh, B. Wetmore, K. Friedman, G. Patlewicz, R. Thomas, R. Sayre, J. Olker, S. Degitz, S. Padilla, J. Harrill, T. Shafer, AND K. Carstens. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS). Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25451677

Judson, R., D. Smith, M. Devito, J. Wambaugh, B. Wetmore, K. Friedman, G. Patlewicz, R. Thomas, R. Sayre, J. Olker, S. Degitz, S. Padilla, J. Harrill, T. Shafer, AND K. Carstens. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS) (Toxics). Toxics. MDPI, Basel, Switzerland, 12(4):271, (2024). https://doi.org/10.3390/toxics12040271

Britton, K., R. Judson, K. Jarema, J. Olin, B. Hill, B. Knapp, M. Lowery, M. Feshuk, J. Brown, AND S. Padilla. Analysis of the Developmental Toxicity Profile of Per- and Polyfluoroalkyl Substances (PFAS) Using a Larval Zebrafish Assay. Carolinas SETAC 2024 Annual Meeting, Boone, NC, April 14 - 16, 2024. https://doi.org/10.23645/epacomptox.25757805

Webb, A., J. Hope, M. Groover, J. Wall, R. Judson, AND R. Sayre. Developing data provenance approaches in ToxValDB: An IRIS Case Study. Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25472164

Sadrpour, P., S. Lynn, R. Judson, AND S. Simmons. Evaluation of Alternative Estrogen Activity Assays for New Computational Models to Support the Endocrine Disruption Screening Program. SOT Conference 2024: A New Approach Method (NAM) to Screen for the Impact of Endogenous Stress on Chemical Toxicity, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25556079

Shirke, A., E. Radke-Farabaugh, C. Lin, R. Blain, N. Vetter, C. lemeris, p. hartman, H. Hubbard, M. Angrish, X. Arzuaga Andino, J. Congleton, J. Davis, L. Dishaw, R. Jones, R. Judson, J. Kaiser, A. Kraft, L. Lizarraga, Pamela Noyes, G. Patlewicz, M. Taylor, A. Williams, Kristina Chialton, AND L. Carlson. Expanded Systematic Evidence Map for Hundreds of Per- and Polyfluoroalkyl Substances (PFAS) and Comprehensive PFAS Human Health Dashboard. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 132(2):CID: 026001, (2024). https://doi.org/10.1289/EHP13423

Harrill, J., L. Everett, D. Haggard, J. Bundy, C. Willis, I. Shah, K. Friedman, D. Basili, A. Middleton, AND R. Judson. Exploring the Effects of Experimental Parameters and Data Modeling Approaches on In Vitro Transcriptomic Point-of-Departure Estimates. TOXICOLOGY. Elsevier Science Ltd, New York, NY, 501:153694, (2024). https://doi.org/10.1016/j.tox.2023.153694

Mansouri, K., J. Moreira-Filho, C. Lowe, N. Charest, T. Martin, V. Tkachenko, R. Judson, M. Conway, N. Kleinstreuer, AND A. Williams. Free and open-source QSAR-ready workflow for automated standardization of chemical structures in support of QSAR modeling. Journal of Cheminformatics. Springer, New York, NY, 16(1):19, (2024). https://doi.org/10.1186/s13321-024-00814-3

Rogers, J., F. Leusch, B. Chambers, K. Daniels, L. Everett, R. Judson, K. Maruya, A. Mehinto, P. Neale, K. Friedman, R. Thomas, S. Snyder, AND J. Harrill. High-Throughput Transcriptomics of Water Extracts Detects Reductions in Biological Activity with Water Treatment Processes. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 58(4):2027-2037, (2024). https://doi.org/10.1021/acs.est.3c07525

Koval, L., L. Everett, J. Harrill, R. Judson, AND J. Rager. Identifying Genes Predictive of Breast Cancer-associated Chemicals through Machine Learning Analysis of High-Throughput Transcriptomic Screening Data across MCF7 Cells. Presented at SOT 2024, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25565265

Truong, K., D. Kapraun, S. Davidson-Fritz, J. Wambaugh, S. Degitz, J. Olker, M. Hornung, R. Judson, AND K. Friedman. In Vitro-In Vivo Extrapolation of Thyroid-Related Endpoints with Higher Throughput Pregnancy PBPK Modeling. Quantitative Systems Pharmacology (QSP) Summit Cambridge 2024, Cambridge, MA, May 01, 2024. https://doi.org/10.23645/epacomptox.25765788

Johnson, J., J. Bundy, J. Harrill, R. Judson, AND L. Everett. In vitro transcriptional points of departure from human whole transcriptome and surrogate transcriptome (S1500+) targeted RNA-Seq assays are highly comparable. 2024 Society of Toxicology Annual Meeting, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25533505

Aurisano, N., P. Fantke, W. Chiu, R. Judson, S. Jang, A. Unnikrishnan, AND O. Jolliet. Probabilistic Reference and 10% Effect Concentrations for Characterizing Inhalation Non-cancer and Developmental/Reproductive Effects for 2,160 Substances. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 58(19):8278-8288, (2024). https://doi.org/10.1021/acs.est.4c00207

Word, L., C. Willis, S. Padilla, C. Weitekamp, K. Carstens, L. Everett, B. Knapp, K. Britton, R. Judson, AND J. Harrill. SOT Conference 2024: A New Approach Method (NAM) to Screen for the Impact of Endogenous Stress on Chemical Toxicity. Society of Toxicology Conference 2024, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25565328

Chang, D., J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, G. Patlewicz, R. Thomas, L. Wehmas, K. Vitense, S. Auerbach, W. Casey, R. Sams, S. Hunter, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/084, 2024. https://doi.org/10.23645/epacomptox.25365550

Harris, F., C. Willis, B. Campos, G. Hodges, S. Cable, A. Middleton, A. Jurgelewicz, R. Judson, AND J. Harrill. Screening Chemicals Using High-Throughput Phenotypic Profiling (HTPP) in Two Zebrafish Cell Lines. SOT Conference 2024: A New Approach Method (NAM) to Screen for the Impact of Endogenous Stress on Chemical Toxicity, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25499740

Brennan, A., D. Chang, J. Cowden, S. Davidson-Fritz, J. Dean, M. Devito, J. Ford, L. Everett, A. Harrill, S. Hester, M. Hughes, J. Lambert, L. Lizarraga, R. Mezencev, D. Macmillan, G. Patlewicz, K. Thayer, R. Thomas, K. Vitense, L. Wehmas, A. Renyer, S. Auerbach, W. Casey, R. Sams, S. Hunter, W. Cascio, K. Holt, S. Jones, R. Subramaniam, G. Rice, J. Bucher, T. Buckley, P. Egeghy, K. Paul-Friedman, J. Harrill, K. Isaacs, R. Judson, J. Kaiser, S. Masten, F. Parham, D. Petersen, A. Phillips, J. Sobus, Dan Villeneuve, P. White, A. Williams, G. Woodall, AND J. Zhao. Standard Methods for Development of EPA Transcriptomic Assessment Products (ETAPs). U.S. Environmental Protection Agency, Washington, DC, EPA/600/X-23/083, 2024. https://doi.org/10.23645/epacomptox.25365496

Rogers, J., J. Bundy, J. Harrill, R. Judson, L. Everett, AND K. Friedman. Transcriptomics and cell morphology screens complement each other when grouping chemicals with similar bioactivity. Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25521205

Dawson, D., Chris Lau, P. Pradeep, R. Sayre, R. Judson, R. Tornero-Velez, AND J. Wambaugh. A Machine Learning Model to Estimate Toxicokinetic Half-Lives of Per- and Polyfluoro-Alkyl Substances (PFAS) in Multiple Species. Toxics. MDPI, Basel, Switzerland, 11(2):98, (2023). https://doi.org/10.3390/toxics11020098

Wambaugh, J., T. Barton-Maclaren, M. Beal, M. Devito, J. Dorne, S. Ferguson, M. Hughes, R. Judson, A. Long, I. Moffat, K. Paul-Friedman, S. Stavroula, R. Thomas, AND B. Wetmore. APCRA Case Study: High Throughput Toxicokinetics for In Vitro-In Vivo Extrapolation. APCRA 7, Helsinki, FINLAND, April 25 - 27, 2023. https://doi.org/10.23645/epacomptox.22647385

Reardon, A., R. Farmahin, A. Williams, M. Meier, G. Addicks, C. Yauk, E. Atlas, J. Harrill, L. Everett, I. Shah, R. Judson, S. Ramaiahgari, S. Ferguson, AND T. Barton-Maclaren. Advancing data interpretation approaches to support the use of transcriptomic points of departure for prioritization and assessment of chemical substances (WC12). 12th World Congress on Alternatives and Animal Use in the Life Sciences (WC12), Niagara Falls, Ontario, CANADA, August 27 - 31, 2023. https://doi.org/10.23645/epacomptox.25048352

Judson, R. Availability of New Approach Methodologies (NAMs) in the Endocrine Disruptor Screening Program (EDSP). Physicians Committee for Responsible Medicine (PCRM) DyNAMic Discussions Webinar Series, virtual, NC, April 14, 2023. https://doi.org/10.23645/epacomptox.22780076

Judson, R. Biosolids Pollutant Prioritization (Biosolids SAB Meeting). Biosolids SAB Meeting, Washington DC, DC, May 02 - 03, 2023. https://doi.org/10.23645/epacomptox.22780106

Judson, R., C. Ring, P. Kruse, D. Tobias, T. Richman, L. Weber, AND E. Greene. Biosolids Pollutant Prioritization (PFAS Science call for State and Tribal partners). PFAS Science call for State and Tribal partners, Virtual, NC, October 30, 2023. https://doi.org/10.23645/epacomptox.24511600

Wetmore, B., K. Paul-Friedman, K. Carstens, J. Harrill, J. Wambaugh, T. Shafer, K. Houck, R. Judson, AND G. Patlewicz. Category-based toxicity and toxicokinetic evaluations of per- and polyfluoroalkyl substances (PFAS) for new approach method (NAM) application. ACS, San Francisco, CA, August 13 - 17, 2023. https://doi.org/10.23645/epacomptox.23845122