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Records 1 to 25 of 61 records from author Mark Higuchi

2024
Rice, O., Q. Krantz, E. Puckett, P. Evansky, K. Wallace, T. Freudenrich, M. Higuchi, AND T. Shafer. Development Of A Novel in Vitro Method to Study Effects of Volatile Compounds on Neural Activity. Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo, Salt Lake City, UT, March 10 - 14, 2024. https://doi.org/10.23645/epacomptox.25407025
Rice, O., Q. Krantz, E. Puckett, P. Evansky, K. Wallace, T. Freudenrich, M. Higuchi, AND T. Shafer. Development of a Novel in Vitro Method to Study Effects of Volatile Compounds on Neural Activity (TSfN). 9th Annual Triangle Society for Neuroscience (TSfN), Durrham, NC, April 26, 2024.
2023
Murray, J., E. Carlsten, J. Weinstein, Todd Krantz, AND M. Higuchi. Development of an aerosol-compatible cell culture exposure system and its application to quantify cellular uptake of particles at the air-liquid interface. Society of Toxicology Annual Meeting, Nashville, TN, March 19 - 21, 2023.
2022
Murray, J., E. Carlsten, W. Zander, J. Weinstein, Todd Krantz, A. Speen, AND M. Higuchi. Aerosolized fluorescent tracers provide insight into particle deposition and cellular uptake at the air-liquid interface. American Society for Cellular and Computational Toxicology (ASCCT) 11th Annual Meeting, Chapel Hill, NC, October 19 - 21, 2022.
Speen, A., J. Murray, Todd Krantz, D. Davies, P. Evansky, J. Harrill, L. Everett, J. Bundy, L. Dailey, W. Zander, E. Carlsten, M. Monsees, J. Hill, J. Zavala, AND M. Higuchi. Benchmark Dose Modeling Approaches for Volatile Organic Chemicals using a Novel Air-Liquid Interface In Vitro Exposure System. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(1):88-107, (2022). https://doi.org/10.1093/toxsci/kfac040
Berg, C., B. Crone, B. Gullett, M. Higuchi, M. Krause, P. Lemieux, T. Martin, E. Shields, E. Struble, E. Thoma, AND A. Whitehill. Developing innovative treatment technologies for PFAS-containing wastes. JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION. Air & Waste Management Association, Pittsburgh, PA, 72(6):540-555, (2022). https://doi.org/10.1080/10962247.2021.2000903
Gavett, S., S. Vance, R. Fannin, A. Fisher, P. Evansky, A. Speen, M. Higuchi, AND Ian Gilmour. Dose-Dependent Respiratory and Proinflammatory Gene Impacts of Acrolein in Mice and Validation of In Vitro Effects. Society of Toxicology, San Diego, California, March 27 - 31, 2022.
2021
Higuchi, M., A. Speen, AND J. Murray. An Approach Using NAMs for the Evaluation of Inhalation Toxicity in OSCPP Chemical Registrations(BOSC). U.S. EPA Board of Scientific Counselors (BOSC) Meeting-Virtual, RTP, NC - Virtual, February 08, 2021.
Higuchi, M., A. Speen, AND J. Murray. Applying NAMs in BMD Analysis and CFD Modeling to Advance In Vitro Inhalation Toxicity Testing. The 11th World Congress on Alternatives and Animal Use in the Life Sciences 2021” Virtual, Maastricht, -virtual, Virtual, NETHERLANDS, August 23 - September 02, 2021.
Speen, A., L. Dailey, Todd Krantz, D. Davies, P. Evansky, J. Harrill, L. Everett, AND M. Higuchi. Bench Mark Dose Modeling Approaches for Volatile Organic Chemical Exposed Human Airway Epithelial Cells at Air-Liquid Interface. Society of Toxicology (SOT) - Virtual, Virtual, RTP, NC, March 12 - 21, 2021.
Kim, Yong Ho, S. Warren, I. Kooter, W. Williams, I. George, S. Vance, M. Hays, M. Higuchi, S. Gavett, D. Demarini, I. Jaspers, AND Matthew Gilmour. Chemistry, lung toxicity and mutagenicity of burn pit smoke-related particulate matter. Particle and Fibre Toxicology. BioMed Central Ltd, London, Uk, 18(1):45, (2021). https://doi.org/10.1186/s12989-021-00435-w
Gavett, S., S. Vance, P. Evansky, L. Copeland, R. Grindstaff, J. Dye, M. Higuchi, AND Ian Gilmour. Dose-Dependent Respiratory Impacts of Acrolein and TCE in Allergic Mice and Validation of In Vitro Effects. Society of Toxicology, NA (virtual meeting), Virtual, March 12 - 26, 2021.
Higuchi, M. Innovative Ways to Destroy PFAS Challenge: ECOS-ASTHO Science Call Update. EPA ECOS-ASTHO Science Call-Virtual, Durham, North Carolina, June 21, 2021.
Kim, Y., C. King, I. George, S. Vance, J. McGee, M. Hays, M. Higuchi, S. Gavett, I. Jaspers, AND Ian Gilmour. Lung Toxicity Testing of Simulated Military Waste Smoke from Smoldering and Flaming Combustions. Society of Toxicology (SOT) - Virtual, NC, RTP, March 14 - 21, 2021.
Murray, J., J. Weinstein, Todd Krantz, AND M. Higuchi. Utilizing Computational Fluid Dynamics Modeling to Create an Aerosol-Specific Cell Culture Exposure System to Evaluate the Toxicity of Aerosols at the Air-Liquid Interface. Society of Toxicology (SOT) - Virtual, Virtual, NC, March 17 - 21, 2021.
2020
Zavala, J., A. Freedman, J. Szilagyi, I. Jaspers, J. Wambaugh, AND M. Higuchi. New Approach Methods to Evaluate Health Risks of Air-Pollutants: Critical Design Considerations for In Vitro Exposure Testing. International Journal of Environmental Research and Public Health. Molecular Diversity Preservation International, Basel, Switzerland, 16(6):e2124, (2020). https://doi.org/10.3390/ijerph17062124
Speen, A. AND M. Higuchi. Volatile Chemical Exposure Comparison for In-Vitro and In-Vivo Benchmark Concentration Analysis. Virtual Meeting-APCRA-5-Accelerating the Pace of Chemical Risk Assessment Meeting, Research Triangle Park, Virtual, August 27, 2020.
2019
Thompson, L., L. Walsh, B. Martin, J. Mcgee, C. Wood, K. Kovalcik, P. Pancras, N. Coates, A. Ledbetter, D. Davies, W. Cascio, M. Higuchi, M. Hazari, AND A. Farraj. Ambient Particulate Matter and Acrolein Co-Exposure Increases Myocardial Dyssynchrony in Mice: Evidence for TRPA1 Involvement. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(2):559-572, (2019). https://doi.org/10.1093/toxsci/kfy262
Smith, G., L. Walsh, M. Higuchi, AND N. Kelada. Development of a Large Scale Computer-Controlled Ozone Inhalation Exposure System for Rodents. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, 31(2):61-72, (2019). https://doi.org/10.1080/08958378.2019.1597222
Kim, Y., C. King, Q. Krantz, M. Hargrove, I. George, J. McGee, L. Copeland, M. Hays, M. Landis, M. Higuchi, S. Gavett, AND Matthew Gilmour. The role of fuel type and combustion phase on the toxicity of biomass smoke following inhalation exposure in mice. Archives of Toxicology. Springer, New York, NY, 93(6):1501-1513, (2019). https://doi.org/10.1007/s00204-019-02450-5
2018
Martin, B., L. Thompson, Y. Kim, W. Williams, S. Snow, M. Schladweiler, P. Phillips, C. King, J. Richards, N. Coates, M. Higuchi, Ian Gilmour, U. Kodavanti, M. Hazari, AND A. Farraj. A High Fat Meal After Peat Smoke Inhalation Unmasks Latent Cardiometabolic Responses in Rats. Annual meeting of the Society of Tooxicology, San Antonio, Texas, March 11 - 16, 2018.
Zavala-Mendez, J., A. Ledbetter, D. Morgan, L. Dailey, E. Puckett, S. McCullough, AND M. Higuchi. A New Cell Culture Exposure System (CCES) for Studying the Toxicity of Volatile Chemicals at the Air-Liquid Interface. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, 30(4):169-177, (2018). https://doi.org/10.1080/08958378.2018.1483983
Farraj, A., B. Martin, L. Thompson, Y. Kim, C. King, S. Snow, M. Schladweiler, N. Coates, I. George, M. Higuchi, Ian Gilmour, U. Kodavanti, AND M. Hazari. Acute Peat Smoke Inhalation Increases Blood Pressure and Cardiac Arrhythmia Risk in Rats. Society of Toxicology Annual Meeting, San Antonio, Texas, March 11 - 16, 2018.
Martin, B., L. Thompson, Y. Kim, W. Williams, S. Snow, M. Schladweiler, P. Phillips, C. King, J. Richards, N. Coates, M. Higuchi, Ian Gilmour, U. Kodavanti, M. Hazari, AND A. Farraj. Acute Peat Smoke Inhalation Sensitizes Rats to the Postprandial Cardiometabolic Effects of a High Fat Oral Load. SCIENCE OF THE TOTAL ENVIRONMENT. Elsevier BV, AMSTERDAM, Netherlands, 643:378-391, (2018). https://doi.org/10.1016/j.scitotenv.2018.06.089
Kim, Y., C. King, Todd Krantz, I. George, M. McGee, L. Copeland, M. Hays, M. Landis, M. Higuchi, S. Gavett, AND Ian Gilmour. Concordance of Pathophysiological Responses in Mice Exposed to Different Biomass Smoke Conditions via Aspiration and Inhalation. Society of Toxicology (SOT), San Antonio, TX, March 11 - 15, 2018.