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This report includes proceedings from the 2013 NIEHS/EPA Children's Centers Annual Meeting, held in Washington D.C. in October, 2013. Summaries of presentations, speaker biosketches, poster abstracts, and a meeting participant list are all included.

The report includes proceedings from the 2015 NIEHS/EPA Children's Centers Annual Meeting. The proceedings include presentation summaries, speaker biosketches, poster abstracts, and a list of meeting participants.

A high level presentation for their senior people, lasting perhaps 45 minutes, covering a history of the protocol program, outcome focused… the why’s and how’s, and how you measure success.

To support the goals articulated in the vision for exposure and risk assessment in the twenty-first century, we highlight the application of a thermodynamic chemical activity approach for the exposure and risk assessment of chemicals in the environment. The present article descri...

From the earliest days of public health, environmental protection has been fundamental to preventing disease and ensuring a healthy population. From John Snow and the Broad Street Pump to chlorinated drinking water in Jersey City, NJ, protecting the environment has been a core pu...

Vegetative leaf area is a critical input to models that simulate human and ecosystem exposure to atmospheric pollutants. Leaf area index (LAI) can be measured in the field or numerically simulated, but all contain some inherent uncertainty that is passed to the exposure assessmen...

Stress tests are used clinically to uncover underlying disease and predict future cardiovascular risk. Previously, we used treadmill exercise stress in rats to reveal latent effects of air pollution inhalation. Other daily stressors, when modeled experimentally, may have similar ...

Background Air pollution risk assessments often employ effect coefficients from epidemiologic studies to quantify the public health impact of changes in air quality. Partly due to data and methodological limitations, epidemiologic studies have traditionally characterized the heal...

The Model for Prediction Across Scales – Atmosphere (MPAS-A) is the meteorological foundation for a next generation global air quality modeling system currently being developed at the U.S. Environmental Protection Agency (USEPA). In recent years, meteorological fields for r...

Despite its importance to transportation safety and ecosystem health related to pollutant and nutrient deposition, the simulation of fog lags the simulation of other meteorological phenomena due in large part to its complexity and limitations of model resolution. Accordingly, th...

The Adverse Outcome Pathway (AOP) framework represents an ideal tool for integrating diverse data relating chemical exposures to adverse outcomes. Glucocorticoid signaling is tightly controlled and numerous adverse health outcomes have been associated with either elevation or sup...

This is the presentation for the invited lecture at Rutgers University. The lecture will be part of online course titled "Sustainability Decision Tools" in Spring 2018.

Researchers who perform air quality modeling studies usually do so on a regional scale. Typically, the boundary conditions are generated by another model which might have a different chemical mechanism, spatial resolution, and/or map projection. Hence, a necessary conversion/inte...

This presentation discusses "accountability"; e.g., do emission-control regulations really reduce exposure to pollutants and improve human health? In this presentation, we provide examples of how to examine this and related questions.

Although epidemiological, human and animal data have conclusively linked air pollution exposure to adverse cardiovascular outcomes, the severity of responses depends on a number of intrinsic (diet, underlying disease, etc) and extrinsic (e.g. co-stressors) factors. As such, cardi...

Wildland fires are increasingly linked to adverse health impacts related to poor air quality. For instance, short-term exposure to smoldering peat (SP) air pollution in eastern North Carolina during separate burns in 2008 and 2011 led to increased cardiopulmonary emergency room v...

Recent studies showed that the circulating stress hormones, epinephrine and corticosterone/cortisol, are involved in mediating ozone-induced pulmonary effects through the activation of the sympathetic-adrenal-medullary (SAM) and hypothalamus-pituitary-adrenal (HPA) axes. Hence, w...

This research paper uses case analysis methods to understand why participants engage in this innovative approach public participation in scientific research, and what they hope that will mean for their community. The research questions that guide this analysis are: 1) what factor...

Air pollution epidemiology studies of ambient fine particulate matter (PM2.5) often use outdoor concentrations as exposure surrogates. These surrogates can induce exposure error since they do not account for (1) time spent indoors with ambient PM2.5 levels attenuated from outdoor...

There currently are a wide variety of approaches emerging to adjust air sensor data, either on the device or more commonly, on a manufacturer's server or cloud. The goal of these adjustments are to correct for measurement artifacts and produce more accurate values. However, most ...

New experimental evidence involving the role of neuroendocrine activation challenges an accepted mechanistic paradigm of how irritant air pollutants induce systemic metabolic impairment and lung injury/inflammation. We focus on recent air pollution studies highlighting how the re...

Air pollution epidemiology studies of ambient fine particulate matter (PM2.5) often use outdoor concentrations as exposure surrogates. These surrogates can induce exposure error since they do not account for (1) time spent indoors with ambient PM2.5 levels attenuated from outdoor...

It is often of interest to model the incidence and duration of threshold exceedance events for an environmental variable over a set of monitoring locations. Such data arrive over continuous time and can be considered as observations of a two-state process yielding, sequentially, ...

Exposure to air pollution-derived particulate matter (PM) causes adverse cardiovascular health outcomes, with increasing evidence implicating soluble components of PM; however, the enormous number of unique PM samples from different air sheds far exceeds the capacity of conventio...

Local, state, federal, tribal and private stakeholders have committed significant resources to restoring Puget Sound’s terrestrial-marine ecosystem. Though jurisdictional issues have promoted a fragmented approach to restoration planning, there is growing recognition that a...